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WASHINGTON, Nov. 24 (Xinhua) -- An inexpensive drug that treats Type 2 diabetes has been shown to prevent a number of natural and man-made chemicals from stimulating the growth of breast cancer cells, according to a newly published study by a Michigan State University researcher. The research, led by pediatrics professor James Trosko and colleagues from South Korea's Seoul National University, provides biological evidence for previously reported epidemiological surveys that long-term use of the drug metformin for Type 2 diabetes reduces the risk of diabetes-associated cancers, such as breast cancers.The research appeared online this week in PLoS One.For the study, Trosko and colleagues focused on the concept that cancers originate from adult human stem cells and that there are many natural and man-made chemicals that enhance the growth of breast cancer cells. Using culture dishes, they grew miniature human breast tumors, or mammospheres, that activated a certain stem cell gene. Then the mammospheres were exposed to natural estrogen -- a known growth factor and potential breast tumor promoter -- and man-made chemicals that are known to promote tumors or disrupt the endocrine system.The team found that estrogen and the chemicals caused the mammospheres to increase in numbers and size. However, with metformin added, the numbers and size of the mammospheres were dramatically reduced. While each of the chemicals enhanced growth by different means, metformin seemed to be able to inhibit their stimulated growth in all cases."While future studies are needed to understand the exact mechanism by which metformin works to reduce the growth of breast cancers, this study reveals the need to determine if the drug might be used as a preventive drug and for individuals who have no indication of any existing cancers," Trosko said.
MANILA, Jan. 9 (Xinhua) -- Philippine telecommunication companies cut off the signal of mobile phones in parts of Manila where millions of people are expected to converge for the feast of the Black Nazarene on Monday.Philippine Deputy Presidential Spokesperson Abigail Valte said that the move was part of the precautionary measures that the government has been undertaking following terror threats."Malacanang (Palace) confirms that the government asked the telcoms to temporarily disconnect their services in the route of the Black Nazarene procession as part of the security measures agreed upon during the meeting on Sunday," she said in a regular news briefing.She said that the disruption in mobile services would last for the entire duration of the procession of the Black Nazarene.She admitted that the signal of the cellular phones was disconnected in the past, and terrorists used the mobile phones as triggering device for bombs.Asked if the government considered the possible losses of telecommunication firms due to the disconnection of signals, Valte said, "as holders of a franchise, the public safety is paramount."President Benigno Aquino III personally warned on Sunday the public to be cautious in joining the feast of the Black Nazarene amid possible terrorist attacks. The government is expecting 9 million devotees to participate in the celebration.The Black Nazarene is the patron saint of Quiapo church. The statue was brought to Manila by a Spanish priest in 1607. It was aboard a ship that caught fire, the image was burned, and it came to be known as the "Black Nazarene" which people have since decided to preserve and honor.
UNITED NATIONS, Nov. 21 (Xinhua) -- Dramatic progress in science, political leadership, and results indicate that 2011 was a "game changing" year for the international AIDS response, and much progress has been made in 2011 to check AIDS-related deaths since 1997, the peak of the epidemic, a new report released by the Joint United Nations Program on HIV/AIDS (UNAIDS) said on Monday."The Report on the Global AIDS Epidemic 2011" found that new infections were reduced by 21 percent since 1997, and deaths from AIDS-related illnesses decreased by 21 percent since 2005, according to the report.Furthermore, 47 percent (6.6 million) of the estimated 14.2 million people eligible for antiretroviral therapy treatment in low- and middle-income countries were accessing treatment, in increase of 1.35 million people since 2009.The report also found early signs that HIV treatment is having an impact on reducing the number of new HIV infections. As treatment reduces the viral load of a person living HIV to almost undetectable levels, it also reduces the risk of transmitting the virus to an uninfected partner, according to the report. Studies also show that treatment can be up to 96 percent effective in preventing HIV transmission among couples.Eleven countries, including many Sub-Saharan African countries, reached "close to universal access" for AIDS treatment, which is determined to be 80 percent access, in 2011.Botswana made the most dramatic progress in scaling up access to treatment, the report said. While sexual patterns remained relatively stable in the country since 2000, access to treatment increased from less than 5 percent in 2000 to more than 80 percent in 2011.Despite progress, however, the report does note that 2011 marks an unprecedented high the number of people infected with HIV worldwide.Globally, an estimated 34 million people are currently living with the infection. Approximately 2.7 million got infected with the virus in 2010, and as many as 1.8 million people died of AIDS- related illnesses in 2010.Yet the report also notes estimates that as many as 2.5 million deaths are estimated to have been averted in low- and middle- income countries due to increased access to HIV treatment since 1995."Now is not the time to reduce our efforts despite some good news on reducing new infections. Infections are decreasing, but not rapidly enough," said Kim Nichols, executive director of African Services Committee, on Monday at a press conference."There are fewer AIDS deaths, but with the number of infections increasing, prevention has to be the mainstay of our response," Nichols said.Indeed, the UNAIDS report calls for a new framework for investments which are focused on "high-impact, evidence-based, high-value strategies," according to a press release from the UNAIDS website.The framework, which aims to achieve universal access to treatment and prevention centers by 2015, requires a 22-24 billion US dollar funding increase by 2015.Given the withering state of the global economy -- donor funding for the AIDS response has dropped from 7.6 billion in 2009 to 6.9 billion in 2010 -- raising that kind of money may be a long shot. Regardless, UNAIDS'new investment plan calls for smarter uses of less money.According to the report, the framework will focus on high-risk populations like sex workers, men who have sex with men, and people who inject drugs and prevent infections among children, as well as invest in behavior change programs, condom promotion, and treatment, care and support for people living with HIV."The world faces a clear choice: maintain current efforts and make incremental progress, or invest smartly and achieve rapid success in the AIDS response," says the UNAIDS report.
BEIJING, Dec. 9 (Xinhua) -- Beijing has seen a declining trend in newly built ordinary apartments in the past 11 months of this year, said a report released by the Beijing Real Estate Association on Friday.That average price of 13,914 yuan (about 2,194.23 U.S. dollars) per square meter from January to November went down 6.3 percent from the yearly average housing price of 14,847 yuan per square meter in 2010, also the target set by the municipal government in attempting to control soaring house prices, said the report.It is expected that the real-estate market in Beijing will maintain the gradually declining trend. And the target of "a stable yearly price with a slight decline" will be smoothly reached, said Chen Zhi, secretary-general of the association.In November, first-time home buyers took up about 90 percent of housing consumers for the ninth month in a row, which means the government's measures to crowd out investing or speculative buying and meet the demands of conventional buyers are working, the report said.This year the government has repeatedly stressed its efforts to contain the runaway property market, through measures including tighter monetary policies, higher down payments, a ban on third-home purchases, price control targets and a trial property tax.
SAN FRANCISCO, Jan. 13 (Xinhua) -- Google seems to get no blessings for a good start for its New Year resolutions as the Internet search giant got an earful of complaints about its new social search service and felt mortified by a customer-poaching scandal in its Kenyan division.On Tuesday, Google announced "search plus your world" to deliver personalized search results by embedding its social service Google+ to its search engine.Although Google called it as "a beautiful journey begins," competitors and industry watchers said it was "a bad day for the Internet." They accused the company of using its dominant search engine to promote its own social networking site by giving Google+ pages and profiles an artificially prominent position in search results.The search giant first had a public bickering with Twitter which issued a statement on Tuesday saying that "As we've seen time and time again, news breaks first on Twitter. We're concerned that as a result of Google's changes, finding this information will be much harder for everyone."Google on Wednesday made a statement on its official Google+ page, saying that "We're a bit surprised by Twitter's comments because they chose not to renew their agreement with us last summer." The agreement, in which Twitter gave Google access to public tweets, expired last July and was not renewed.Twitter fired back by demonstrating the inefficiency of the new Google search feature. Twitter general counsel Alex Macgillivray tweeted a page of Google search results for the search term "@WWE" which did not include World Wrestling Entertainment's Twitter page, but Google+ page.Macgillivray noted that with 792,642 followers on Twitter compared with 24,900 followers on Google+, WWE's Twitter page is a more relevant social source than Google page and should be presented in Google's search results.Facebook, Google+'s major rival, has been remaining silent this week publicly while its employees criticized Google's moves in public status updates. Several prominent Facebook engineers and directors shared a tech blog about switching default search engine to Microsoft's Bing after "Google broke itself."Facebook has been working with Microsoft to allow Bing to reveal more personalized content.Industry watchers are also crying foul at the privacy and antitrust concerns raised by the new search feature. Search Engine Land, a tech blog closely following Google's news, posted several examples of how Google favors its own social networking service.Industry watchdog Electronic Privacy Information Center told the Los Angeles Times that the group is considering filing a complaint with the U.S. Federal Trade Commission (FTC). The organization once made the complaint that resulted in Google's settlement with the FTC last year that requires the Mountain View, California-based company to submit to external audits of their privacy practices every other year.On Friday, a Kenyan business directory startup Mocality said that Getting Kenyan Businesses Online, a Google-backed initiative to give small businesses free websites for one year, routinely accessed Mocality's database to obtain sales leads.The Search giant's Kenyan division called Mocality customers to pitch Google's alternative service, claiming they have had a partnership with Mocality. Mocality CEO Stefan Magdalinski said there is no such partnership.In a statement sent to the U.S. media, Google said it is " mortified" to learn that a team representing Google improperly used Mocality's data and misrepresented their relationship with the Kenyan company, noting that it "unreservedly apologized to Mocality" and is still investigating the issue.On Monday, BBC revealed that Google admitted profiting from advertisements of illegal websites selling drugs, fake passports and unauthorized tickets for the 2012 Olympics.The ads had been removed by Google after they were brought to the company's attention, but the search giant told BBC that the company "keeps any money it might make from companies advertising illegal services before such ads are removed."Meanwhile, on Thursday, Microsoft announced it has signed a patent licensing agreement with LG Electronics on the manufacturer 's devices running Google Android platform, leaving Motorola Mobility the only major Android-powered device maker that refuses to strike a deal with Microsoft.After the announcement, Microsoft's directors have been taking to Twitter to taunt Google as the two companies had a history of public back-and-forth. But so far, it appeared that Google didn't have time to needle back.