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BEIJING, August 1 (Xinhuanet) -- U.S. researchers have discovered a genetic mutation unique to African Americans that links to heighten their asthma risk, according to reports published on Sunday in the journal Nature Genetics.Researchers of University of Chicago found a gene, PYHIN1, and its variations may account for asthma risk in people of African descent. In their study, they examined data from nine previous genome-wide association studies, totaling more than 2 million single nucleotide polymorphisms in 3,246 asthma patients and 3,385 control patient, 1,702 patient-parent groupings, 355 family-based cases, and 468 family-based controls.In the study, the researchers found that between 26 percent and 29 percent of people of African-descent carried at least one copy of the gene.  In particular, one polymorphism of the gene was 34 percent more likely found in African-American and Afro-Caribbean people with asthma.  More interestingly, this variant of the gene is rarely found in Caucasian people and in Latino population, it was found in less than 5 percent.This new variant is part of a family of genes linked with the body's response to viral infections. It is thought to be involved in interferon signaling, which could influence the occurrence of asthma.The team stressed that each gene variant on its own plays only a small role in increasing asthma risk, but that risk could be multiplied when combined with other risk genes and with environmental factors.

LOS ANGELES, June 7 (Xinhua) -- Salmonella, not E. coli, poses the greatest health threat to Americans, the U.S. Centers for Disease Control and Prevention (CDC) announced on Tuesday.Salmonella infections have risen 10 percent over the past 15 years, while several types of foodborne illness have been falling, the agency said in a report.Infections from Shiga toxin-producing E. coli O157 (the strain of most concern in the United States) have dropped almost in half and the rates of six other foodborne infections have been cut 23 percent, the CDC said.The agency issued the report as a deadly new strain of E.coli is spreading in several European countries."There are about 50 million people each year who become sick from food in the U.S.. That's about one in six Americans," CDC director Dr. Thomas R. Frieden said.The CDC attributed the reduction in infections from E. coli O157 to better detection and investigation of outbreaks, cleaner slaughterhouse methods, better testing of ground beef for E. coli, improved inspections of ground beef processing plants, regulations prohibiting E. coli O157 in ground beef and increased awareness of the importance of properly cooking beef.Other foodborne illnesses that fell in incidence over the same time period include those caused by the campylobacter, listeria, vibrio and yersinia pathogens.To reduce their risk of foodborne illness, people should assume that raw chicken and other meat have bacteria that can make you sick, the CDC said.In the kitchen, raw meats should not allow to contaminate counter tops or cutting boards and should be kept away from other foods, such as fruits and vegetables, the CDC advised.The agency also called on people to thoroughly cook meat, poultry, eggs and shellfish, while refraining from consuming unpasteurized milk, juice or soft cheese.

WASHINGTON, Aug. 2 (Xinhua) -- The weakness of aging is associated with leaky calcium channels inside muscle cells and a drug already in Phase II clinical trials for the treatment of heart failure might plug those leaks, according to a report published Tuesday in the online edition of Cell Metabolism.Earlier studies by the research team led by Andrew Marks of Columbia University showed the same leaks underlie the weakness and fatigue that come with heart failure and Duchenne muscular dystrophy."It's interesting, normal people essentially acquire a form of muscular dystrophy with age," Marks said. "The basis for muscle weakness is the same." Extreme exercise like that done by marathon runners also springs the same sort of leaks, he added, but in that case damaged muscles return to normal after a few days of rest. A microscopic view shows smooth muscle cells derived from human embryonic stem cells showing the nuclei (blue) and proteins of the cytoskeleton (green) in this handout photo released to Reuters by the California Institute for Regenerative Medicine, March 9, 2009The leaks occur in a calcium release channel called ryanodine receptor 1 (RyR1) that is required for muscles to contract. Under conditions of stress, those channels are chemically modified and lose a stabilizing subunit known as calstabin1.Calcium inside of muscle cells is usually kept contained. When it is allowed to leak out into the cell that calcium itself is toxic, turning on an enzyme that chews up muscle cells. Once the leak starts, it's a vicious cycle. The calcium leak raises levels of damaging reactive oxygen species, which oxidize RyR1 and worsen the leak.The researchers made their discovery by studying the skeletal muscles of young and old mice. They also showed that 6-month-old mice carrying a mutation that made their RyR1 channels leaky showed the same muscular defects and weakness characteristic of older mice.When older mice were treated with a drug known as S107, the calcium leak in their muscles slowed and the animals voluntarily showed about a 50 percent increase in the amount of time spent wheel running. Now in clinical trials for patients with heart failure, the drug is known to work by restoring the connection between costabilin and RyR1.Despite considerable effort to understand and reverse age- related muscle wasting, there are no established treatments available. The new work suggests there may be hope in approaching the problem from a different angle."Most research has focused on making more muscle mass," Marks said. "What's different here is that we are focused not on muscle mass but on muscle function. More muscle doesn't help if it is not functional."

LOS ANGELES, July 6 (Xinhua) -- NASA scientists have got the first-ever, up-close details of a Saturn storm that is eight times the surface area of Earth, the Jet Propulsion Laboratory ( JPL) announced on Wednesday.The images were captured by NASA's Cassini spacecraf, according to JPL in Pasadena, Los Angeles.On Dec. 5, 2010, Cassini first detected the storm that has been raging ever since. It appears approximately 35 degrees north latitude of Saturn.The storm is the biggest observed by spacecraft orbiting or flying by Saturn. NASA's Hubble Space Telescope captured images in 1990 of an equally large storm.Pictures from Cassini's imaging cameras show the storm wrapping around the entire planet covering approximately two billion square miles (4 billion square kilometers).The storm is about 500 times larger than the biggest storm previously seen by Cassini during several months from 2009 to 2010. At its most intense, the storm generated more than 10 lightning flashes per second.Cassini has detected 10 lightning storms on Saturn since the spacecraft entered the planet's orbit.Those storms rolled through an area in the southern hemisphere dubbed "Storm Alley." "Cassini shows us that Saturn is bipolar," said Andrew Ingersoll, a Cassini imaging team member at the California Institute of Technology in Pasadena, California. "Saturn is not like Earth and Jupiter, where storms are fairly frequent. Weather on Saturn appears to hum along placidly for years and then erupt violently. I'm excited we saw weather so spectacular on our watch."The new details about this storm complement atmospheric disturbances described recently by scientists using Cassini's composite infrared spectrometer and the European Southern Observatory's Very Large Telescope. The Cassini-Huygens mission is a cooperative project of NASA, the European Space Agency and the Italian Space Agency. NASA's JPL manages the mission for the agency's Science Mission Directorate in Washington.

BEIJING, Aug. 2 (Xinhuanet) -- The first close-up pictures of the asteroid Vesta, a protoplanet that dates back to the early days of the solar system, were revealed Monday by NASA scientists.The images were taken by the U.S. space agency's Dawn robotic probe, which is two weeks into a planned year-long survey of the second largest object in the main asteroid belt, located between Mars and Jupiter.About twice the size of California, Vesta is second in size only to Ceres, Dawn's next target and, along with Pluto, one of just five known dwarf planets. NASA is spending 466 million dollars to explore Vesta and Ceres during the course of a 10-year mission.Images from Dawn show Vesta a surprisingly diverse terrain and several unexplained geologic features. Chaotic terrain near the south pole is dominated by a towering central peak and huge ripple-like grooves stretching around its equatorial belt. Bright spots, dark pits and craters are filled with unexplained streaks of black and white debris. Terrain north of the grooves is much more heavily cratered.Scientists believe Vesta grew from a clump of gas and dust left over after the sun's birth some 4.65 billion years ago, a supernova explosion, which added radioactive materials to the growing body.Dawn will spend about a year circling Vesta, tweaking its orbit and altitude using an innovative technology called ion propulsion system, chief engineer Marc Rayman with NASA's Jet Propulsion Laboratory in California said.The ion propulsion system will enable Dawn to leave Vesta's orbit after a year of study and head off to Ceres, which is the largest object in the asteroid belt.