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BEIJING, May 10 (Xinhuanet) -- Professional social networking site LinkedIn is aiming for a valuation of 3.3 billion U.S. dollars for its initial public offering, media reports said Tuesday.The Mountain View, California-based company is expected to begin trading on the New York Stock Exchange within the next month and will use the symbol "LNKD."It plans to offer 7.84 million shares priced at 32 dollars to 35 dollars each, according to the filing, which it submitted to the Securities and Exchange Commission.LinkedIn, which has more than 100 million members in over 200 countries and territories, is seeking to raise as much as 274.4 million dollars from the initial public offering (IPO) with 146.6 million dollars going to the company itself.In 2010, LinkedIn made 15 million dollars in profit on 243 million dollars in revenue, according to the filing.LinkedIn's biggest shareholder is its founder and chairman, Reid Hoffman, who owns more than 21 percent of the company.
BEIJING, Jan. 24 (Xinhua) -- China's top economic planner said Monday that price supervision and control measures have achieved steady progress with 2010's Consumer Price Index, slightly exceeding the target ceiling by 0.3 percentage points to hit 3.3 percent.To rein in soaring commodities prices, joint efforts have been made to manage inflation expectations, promote production, ensure supplies and strengthen price supervision in 2010, said the National Development and Reform Commission (NDRC) in an online statement.Prices of necessities accelerating during the second half of 2010 have been contained with vegetable prices down 9.4 percent in December from the previous month last year, it said.Further, prices of edible vegetable, pork, egg, sugar,liquefied petroleum gas and clothing also decreased significantly in December month on month, the statement said.To cope with rising prices beginning in July 2010, especially prices of basic supplies, the central government promptly introduced joint inter-ministerial meetings to discuss price controls among 17 ministries and ordered local governments to establish the same mechanism, it noted.Local governments have worked on improving agricultural facilities, especially in south China's Hainan province, to increase vegetables supplies for northern cities over the past year, the statement said.The statement forecasts that vegetable planting areas in 2010's autumn and winter will increase 530,000 hectares year on year, sending output to 337 million tonnes.To ensure production and supply, departments have worked to reduce fertilizer exports and promote links between production areas and purchasing areas, it added.Further, relevant authorities also took measures to stabilize prices of electricity and coal, and to ensure smooth transportation of agricultural produce.Authorities also granted temporary subsidies and raised basic wages and minimum living subsidies for urban and rural residents to guarantee people's daily life.

BEIJING, March 10 (Xinhuanet) -- The price of preventing preterm labor is about to rise drastically in the U.S. next week.A drug for high-risk pregnant women costs about 10 to 20 dollars per injection. Next week, the price will shoot up to 1,500 dollars a dose, according to media reports Wednesday.This means the total cost during a pregnancy could be as much as 30,000 dollars.The massive increase comes after KV Pharmaceutical of St. Louis won an exclusive government license to produce the drug, known as Makena.The drug, a form of progesterone given as a weekly shot, has been made cheaply for years by unlicensed chemists.The March of Dimes and many obstetricians supported the move because it means quality will be more consistent and it will be easier to get, but none of them has anticipated the sharp price hike.Doctors and campaign groups have been caught out by the move, saying that the price hike may deter low-income women from getting the drug, leading to more premature births.
WASHINGTON, April 25 (Xinhua) -- A class of drugs that shows promise in breast and ovarian cancers with BRCA gene mutations could potentially benefit colorectal cancer patients with a different genetic mutation, a new study from the University of Michigan Comprehensive Cancer Center finds.Working in cell lines from colorectal cancer patients, researchers found that the class of drugs called PARP inhibitors worked against tumors with mutations in the MRE11 gene.About 15 percent of all colorectal cancers have what's called microsatellite instability, a type of error in the DNA. About 82 percent of those tumors have the MRE11 gene mutation."This is a potential broader application for PARP inhibitors, beyond breast and ovarian cancer. This is a class of drug that's already shown safety in early clinical trials and now might benefit some colorectal cancer patients as well," says lead study author Eduardo Vilar-Sanchez, a hematology/oncology fellow at the university, in a statement.The study, which was published Monday in Cancer Research, also found that PARP inhibitors are even more effective when both copies of MRE11 were mutated. Each person carries two copies of each gene, which means mutations can occur in either one or both copies. The researchers suggest that PARP inhibitors could be targeted specifically to colorectal cancer patients who have two copies of the mutated gene.Researchers are planning a phase I clinical trial to look at using PARP inhibitors in colorectal cancer patients with two mutated copies of MRE11. Future trials are being considered using PARP inhibitors to prevent colorectal cancer and other cancers in people with Lynch syndrome whose tumors have this mutation.Microsatellite instability is also seen in prostate cancer and endometrial cancer, suggesting potential for PARP inhibitors to play a role in additional types of cancer as well, Vilar-Sanchez says, adding that more research is needed in these areas.
CHICAGO, Jan. 21 (Xinhua) -- Chinese President Hu Jintao, on a trip to the United States, Friday visited an exhibition of companies operating in the U.S. Midwest.Most companies present at the exhibition, which was held in Chicago's suburban city of Woodridge, are Chinese-funded ones.During the visit, Hu encouraged Chinese companies operating in the United States to play a bigger role in promoting economic and trade cooperation between the two countries.Chinese President Hu Jintao visits an exhibition of companies operating in the U.S. Midwest, in Chicago, the United States, Jan. 21, 2011. Most companies present at the exhibition are Chinese-funded ones.The success of Chinese companies in the United States is a specific example of the China-U.S. mutually beneficial cooperation, he added.The operation of these companies not only yields profits for themselves, but adds momentum to economic development in the U.S. Midwest.Hu flew to Chicago after finishing a visit to Washington Thursday afternoon.He will wrap up his four-day state visit to the United States later Friday.
来源:资阳报