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BEIJING, Aug. 22 (Xinhuanet) -- Researchers have discovered how a human egg captures an incoming sperm for fertilization, paving the way to help couples suffering from infertility, according to media reports on Monday.An international team of researchers found that a sugar chain known as the sialyl-lewis-x sequence (SLeX) makes the outer coat of the egg “sticky,” which has proven to be helpful in binding the egg and the sperm.As a result, this observation has filled in a huge gap in the understanding of fertility and provides hope for ultimately helping couples who currently cannot conceive.Scientists and doctors know that a sperm identifies an egg when proteins on the head of the sperm match and bind to a series of specific sugars in the egg’s outer coating. With a successful match of proteins, the outside surfaces of the sperm and egg then bind together before merging, which is then followed by delivery of sperm’s DNA into egg.To identify this molecules, the researchers used ultra-sensitive mass-spectrometric imaging technology to observe and identify which molecules are most likely to be key in the binding process.They experimented with a range of synthesised sugars in the laboratory and found that it is SLeX that specifically binds sperm to an egg.According to the World Health Organisation, infertility affects about 15 percent of reproductive-aged couples around the world and almost one in every seven couples in Britain has problems conceiving a child for various reasons.
XIAMEN, June 12 (Xinhua) -- Chinese mainland on Sunday announced a raft of measures on tourism, transportation, farmers and food safety to boost Taiwan's economic growth and cross-Strait relations.A pilot plan allowing mainlanders to visit Taiwan as individual tourists will start on June 28, which covers residents of Beijing, Shanghai and southeastern city of Xiamen at the first stage, said Wang Yi, head of the State Council's Taiwan Affairs Office.Wang told a conference at the weeklong Straits Forum being held in Xiamen of Fujian Province that the mainland and Taiwan also agreed to allow Fujian residents to visit the islands of Kinmen, Matsu and Penghu in the Taiwan Strait as individual tourists.Observers predict that the influx of mainland tourists will bring vitality to Taiwan's export-oriented economy which had greatly suffered from the global economic downturn.Currently, mainlanders are only allowed to visit Taiwan on package tours after the authorities lifted a partial ban in July 2008.At Sunday's conference, the two sides also announced to increase the number of cross-Strait passenger flights by more than 50 percent to 558 flights per week, and add terminals for the direct flights in four mainland cities, including one in northwestern city of Lanzhou, which brought the total number of cross-Strait flight terminals to 50 on both sides of the Strait.The moves aim to cope with the increasing number of mainlanders who wish to visit Taiwan.The number of mainland tourists traveling to the island reached 2.34 million as of the end of May, China's top tourism official said at the conference. There are also an increasing number of mainland business travelers and government delegations visiting Taiwan.Meanwhile, both sides agreed to "regulate airfares" for flights from Beijing and Shanghai to Taipei.Currently, the cheapest one-way ticket between Beijing and Taipei on Air China, the mainland's flagship carrier, costs around 1,300 yuan (about 200 U.S. dollars) while a full price one-way ticket costs more than 3,000 yuan, according to the airline's website.Some members of the public on both sides have complained about the high price.For the past decades, travelers had to transfer at other airports, particularly the one in Hong Kong, in order to reach Taiwan by air.In 2003, the two sides agreed to operate charter flights during Spring Festival, China's biggest public holiday.Regular direct flights across the Strait have been available since July 2008 to mainly serve mainland package tourists visiting Taiwan.The mainland also decided to facilitate entry and exit procedures for Taiwan residents and lower charges for endorsing their passports by 50 percent starting from July 1.Meanwhile, four "enterprising parks" will be set up in four cities of Fujian, central Henan and southwestern Guangxi provinces for Taiwan farmers launching agricultural startups on the mainland, said Wang Yi.Both sides also agreed to encourage mainland enterprises to purchase farm produce and other products listed in the early harvest program of the cross-Strait Economic Cooperation Framework Agreement (ECFA) directly in Taiwan.A general manager surnamed Lin of a farm produce company in Taiwan's southern city of Tainan said he hoped to seize the opportunity to benefit from the development of the island's farm and fishing sector as the mainland has become Taiwan's largest export market.Further, both sides agreed to strengthen cooperation and exchanges concerning nuclear power security and food safety.The third Straits Forum, which opened Saturday in Xiamen, facing Taiwan across the Strait, will close in the island's city of Taichung on Friday.
SAN FRANCISCO, Aug. 10 (Xinhua) -- Amazon on Wednesday launched Kindle Cloud Reader, a web-based app that may help the on-line retailer to sidestep Apple's App Store restrictions.In its announcement, Amazon said Kindle Could Reader uses the HTML5 web standard to let users read e-books from their Kindle library from the Safari browser or Google's Chrome browser on their desktops or tablet, including the iPad.Support for Internet Explorer, Firefox and the Blackberry Playbook will be launched later this year.The app has a button linked to the Kindle Store, which was removed recently from the Kindle apps for iPad and iPhone.The move is taken as an answer to Apple's latest App Store restrictions, which banned developers to have any external links for purchasing digital books or subscriptions in the app, unless they give Apple a 30 percent cut from the in-app sales.Besides Amazon, Barnes & Noble, Google Books and Canadian e- book seller Kobo have also altered their iPad and iPhone apps to comply with the rules.Meanwhile, publishers and retailers have been developing web- based HTML5 apps to sidestep Apple for more control, which is an approved-of technology for iOS devices.The Financial Times, Kobo and video-on-demand service Vudu have recently launched their HTML5 app to avoid paying Apple a 30 percent cut.Industry watchers said it is unknown how Apple will deal with such apps. It would be easy for Apple to disable Web apps in the iPad's Safari browser, but the company would certainly face some backlash, said tech media website CNET.
BEIJING, July 26 (Xinhuanet) -- Seven of the 20 top selling American prescription drugs will lose their patents by the end of next year, making way for less expensive generic versions, according to media reports.It's a shift that could save consumers billions of dollars -- assuming those big-ticket medications are willing to give up a trusted brand name for an off-label replacement.The prices of medications such as cholesterol-fighting Lipitor and blood thinner Plavix are expected to go down significantly, according to the U.S. Food and Drug Administration (FDA).Lipitor will lose its patent in November. When that patent expires, people are advised to buy atorvastatin, the generic equivalent. Other brand names include the anti-psychotic Zyprexa and the rheumatoid arthritis and psoriasis drug Enbrel, of which the patent will expire in October and October of next year, respectively.Over the next 10 years, an estimated 120 more brand-name prescription drugs will lose their patents in the U.S.
WASHINGTON, June 6 (Xinhua) -- Women who have higher levels of the appetite-controlling hormone leptin have fewer symptoms of depression, and this apparent inverse relationship is not related to body mass index (BMI), a new study finds. The results were presented Monday at The Endocrine Society's 93rd Annual Meeting in Boston, the United States."Animal data suggest that leptin may reduce anxiety and improve depression. Our study in women suggests that leptin may indeed have antidepressant qualities," said the study's lead author, Elizabeth Lawson, of Massachusetts General Hospital and Harvard Medical School in Boston.Leptin, the product of fat cells, signals satiety, or fullness. It is low in thin women and high in obese women, according to Lawson. She also said there is an increased prevalence of anxiety and depression in certain conditions in which leptin levels are typically low. These include the eating disorder anorexia nervosa, in which there is abnormally low weight and body fat, and functional hypothalamic amenorrhea, in which women have stopped menstruating despite having normal weight."It is unknown whether low leptin levels contribute to the development of mood disorders in these women," Lawson said.She and her co-workers studied the relationship between leptin levels and symptoms of anxiety and depression in 64 women. Fifteen of the women had anorexia nervosa, 12 were normal weight with hypothalamic amenorrhea, 20 were normal weight and in good health, and 17 were overweight or obese but still healthy.All subjects were asked questions to assess symptoms of depression and anxiety, with high scores indicating more symptoms. Besides measuring leptin levels in the blood, the researchers assessed the women's BMI, a measure of weight for height.The relationship between leptin and depression symptoms was independent of BMI. This finding indicates that leptin may mediate symptoms of depression and that this effect is not a function of low weight, Lawson said."Further research administering leptin to humans will be important in understanding whether this hormone has a potential role in the treatment of depression," she said.