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BEIJING, May 24 (Xinhuanet) -- Scientists revealed for the first time the molecular structure of proteins, which enables bacteria to transfer electrical charges, according to a new study. The revelation was published in Proceedings of the National Academy of Sciences in the U.S. on Monday.Scientists used a technique called "x-ray crystallography" to reveal the molecular structure of proteins, which work as atom-sized "wires" discharging excess electricity."This is an exciting advance in our understanding of how some bacterial species move electrons from the inside to the outside of a cell," said lead author Tom Clarke of the University of East Anglia's School of Biological Sciences in Norwich, England.He said this discovery means "We can now start developing efficient 'bio-batteries' as the viable energy source in the future."Still, it could take perhaps a decade to go. Before that, existing uses of such bacteria needed to become 100 or 1,000 times more efficient, he said.The advance could also hasten the development of microbe technology that can help clean up oil or uranium pollution, he said.Microbes might in future be enlisted to clean up nuclear accidents such as Japan's Fukushima Daiichi disaster, he added.
WASHINGTON, April 6 (Xinhua) -- A study led by researchers at the University of Michigan (U-M) showed in animal studies that new cancer drug compounds they developed shrank tumors, with few side effects.The study, done in two mouse models of human cancer, looked at two compounds designed to activate a protein that kills cancer cells. The protein, p53, is inactivated in a significant number of human cancers. In some cases, it is because another protein, MDM2, binds to p53 and blocks its tumor suppresser function. This allows the tumor to grow unchecked. The new compounds block MDM2 from binding to p53, consequently activating p53."For the first time, we showed that activation of p53 by our highly potent and optimized MDM2 inhibitors can achieve complete tumor regression in a mouse model of human cancer," says lead study author Shaomeng Wang, director of the Cancer Drug Discovery Program at the U-M Comprehensive Cancer Center.Wang presented the study Wednesday at the American Association for Cancer Research 102nd annual meeting.Many traditional cancer drugs also activate p53 but they do so by causing DNA damage in both tumor cells and normal cells, causing side effects. These new MDM2 inhibitors activate p53 while avoiding the DNA damage common with other drugs. In this study, which was done in collaboration with Ascenta Therapeutics and Sanonfi-Aventis, researchers showed that these new drugs shrank tumors without significant side effects.Because p53 is involved in all types of human cancer, the new drug has potential to be used in multiple types of cancer. Further, the researchers also identified certain markers in tumors that predict which ones will be particularly sensitive to the MDM2 inhibitor, which would allow physicians to target the drug only to patients most likely to benefit.
BEIJING, May 10 (Xinhuanet) -- Researchers from California, Unated States, found that sexual orientation could play a role in cancer and more gay men are reported being cancer survivors than straight men, according to findings in the journal Cancer online Monday.The researchers found that gay men are 1.9 times more likely than straight men to report having had cancer. They also found that lesbian and bisexual women are more than twice as likely as heterosexual women to report fair or poor health after having cancer.Researchers looked at three years of responses to the California Health Interview survey, which included more than 120,000 adults living in the state.Among other health-related questions, participants were asked if they had ever been diagnosed with cancer and whether they identified as gay, lesbian, bisexual, or straight.Out of 51,000 men, about 3,700 said they had been diagnosed with cancer as an adult. While over 8 percent of gay men reported a history of cancer, that figure was only 5 percent in straight men, a disparity that could not be attributed to differences in race, age or income.About 7,300 out of 71,000 women in the study had been diagnosed with cancer, but overall cancer rates did not differ among lesbian, bisexual, and straight women.Ulrike Boehmer, the study's lead author from the Boston University School of Public Health, said higher rates of human immunodeficiency virus (HIV) may be related to the increased risk of cancer in gay men.However, the findings do not necessarily mean that being gay, lesbian or bisexual increases risk of cancer, said the researcher.
MOSCOW, Jan. 24 (Xinhua) -- Russian President Dmitry Medvedev and visiting Chinese State Councilor Dai Bingguo held talks here on Monday, discussing prospects for the development of cooperation between the two countries.Medvedev and Dai Bingguo discussed the development of Russian- Chinese bilateral cooperation and interaction on the international arena.The Russian president said the Sino-Russian strategic partnership of coordination is developing further in all aspects, as the leaders of the two nations kept close contact during last year and cooperation in the economic and trade sphere has been deepened.Russia sees China as its closest partner, a position that will never be changed, Medvedev stressed.Russia is willing to work together with China to promote all- around cooperation and coordination on international and regional issues, Medvedev said.He said the strategic security talks between Russia and China, a major goal of Dai's current visit, have served as an important channel for bilateral coordination and exchanges, and played a pivotal role in enhancing bilateral strategic mutual trust.Dai Bingguo, who arrived in Moscow Sunday for a three-day visit, said that the first ten years of the 21st century had been important for Sino-Russian relations.China attaches great importance to the strategic coordination with Russia and is willing to work with Russia to develop their strategic partnership of coordination at a higher stage, the Chinese state councilor said.
WUXI, Jiangsu, Feb. 17 (Xinhua) -- Chinese Vice Premier Zhang Dejiang said Thursday that developing quality labor and vocational skills would greatly contribute to the social and economic development of the Asia-Pacific region.He made the remarks while delivering a speech at the opening ceremony for the APEC (Asia Pacific Economic Cooperation) Skills Development Promotion Center which was launched in China's eastern city of Wuxi.The Center will play a positive role in enhancing human resources cooperation between APEC members and achieve "inclusive growth" in the region, Zhang said.The Chinese government has always held that human resources are the most important resource in social and economic development, and it would continue to actively take part in APEC activities that encourage regional exchanges and cooperation in human resource development, he said.China would fully support the APEC Skills Development Promotion Project and the development of the center with financial and technical backup, making it a platform for vocational training and personnel exchanges between APEC members, he added.The decision to establish the center was announced by Chinese President Hu Jintao during the 18th APEC Economic Leaders' Meeting in November last year, which sought to advance cooperation on human resources within the APEC framework.