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A New York appeals court has cleared the way for a publisher to distribute a tell-all book by President Donald Trump's niece over the objections of the president's brother. The New York State Supreme Court Appellate Division issued the written decision late Wednesday. The appeals court lifted a restraint that a judge put on Simon & Schuster that sought to block its distribution. But it left in place restraints against Mary Trump. She's the author of “Too Much and Never Enough: How My Family Created the World’s Most Dangerous Man.” The publisher, Simon & Schuster, and a lawyer for Mary Trump praised the ruling. An email seeking comment was sent to a lawyer for Robert Trump, who sued Mary Trump. 718

A subject coughing in a cyclic incident. A qualitative examination of airborne droplet transmission with and without wearing a surgical mask. The top and bottom figures show the results at 2 s and 3 s, respectively. Wearing a surgical mask that exhibits an initial efficiency of ～91%. This cannot prevent the transport of the saliva droplets away from the subject. Many droplets penetrate the mask shield and some saliva droplet disease-carrier particles can travel more than 1.2 m. For visualization, the droplets were scaled by a factor of 600 compared to their actual size. The environmental conditions are zero wind speed, ambient temperature 20 °C, pressure 1 atm, and relative humidity 50%. The mouth temperature is 34 °C and the face skin temperature is 32 °C. 775

A third leading candidate COVID-19 vaccine has entered a final stage of human testing in the United States. AstraZeneca announced Monday its potential COVID-19 vaccine has entered final trials in the U.S. to test the effectiveness and safety of the product. The Cambridge, England-based company said the trial will involve up to 30,000 adults from various racial, ethnic and geographic groups. The potential vaccine was invented by the University of Oxford and an associated company, Vaccitech.AstraZeneca said development of the vaccine known as AZD1222 is moving ahead globally with late-stage trials in the U.K., Brazil and South Africa. Further trials are planned in Japan and Russia.“To have just one vaccine enter the final stage of trials eight months after discovering a virus would be a remarkable achievement; to have three at that point with more on the way is extraordinary,” Health and Human Services Secretary Alex Azar said in a statement.Two other vaccine candidates began final testing this summer in tens of thousands of people in the U.S. One was created by the National Institutes of Health and manufactured by Moderna Inc., and the other developed by Pfizer Inc. and Germany’s BioNTech. 1215

A small town in Canada's Saskatchewan province is in mourning Saturday after 15 people died when a bus carrying a junior hockey team collided with a tractor-trailer. At least 14 are being treated for injuries."This is a dark moment for our city, our community, our province," Humboldt Mayor Rob Muench said Saturday afternoon at a news conference. "There is no playbook on what to do in cases like this. 411

A police officer, a doctor and a pharmaceutical assistant were killed after a Monday afternoon shooting at Chicago's Mercy Hospital, Mayor Rahm Emanuel said.The shooting was a domestic incident, Chicago Police Superintendent Eddie T. Johnson said. The gunman's first victim was a woman he had previously had a relationship with, Johnson said.The gunman also died, though it is unclear whether he died from police gunfire or a self-inflicted gunshot wound, Johnson said.In a statement Monday, Mercy Hospital named its employees killed in the shooting as emergency room physician Tamara O'Neal and pharmacy resident Dayna Less -- a 25-year-old recent graduate of Purdue University.PHOTOS: Multiple people dead in Chicago hospital shootingThe hospital paid tribute to police and security staff, saying it was "deeply saddened by the tragedy.""Every shooting in America is a tragedy, and it is especially senseless when a shooting occurs in the healing space of a hospital," it said.Chicago Police identified the deceased officer as Samuel Jimenez, a father of three. He joined the force in February 2017 and recently completed probationary training, becoming a full-fledged officer, Johnson said. A procession was held for him Monday night."Today, we mourn Chicago Police Officer Samuel Jimenez. His heroic actions saved countless lives. He ran toward danger. He ran toward those shots. He ran into fire. Selflessly,"?the department said on Twitter."What I would ask is that you keep all the victims of today's horrific incident in your thoughts and prayers," Johnson said. 1578