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SAN DIEGO (KGTV) – The coronavirus has touched the lives of people of all ages, but none more than seniors. Despite ongoing challenges, residents at a senior living facility are finding ways to stay positive.You can’t see their smiles but you can tell they’re there.Residents at Belmont Village Senior Living in Sabre Springs are not only adapting to the pandemic, they’re overcoming it through "The Joys of Life."Don Bodow started the program to spread happiness and stimulate minds. Through a series of puzzles, games, and activities he helps fellow residents stay positive.“I’m making other people happy,” said Bodow. “Giving them joy simply makes me feel good.”Although they can’t be with their families during the pandemic, many are happy right where they are.“The joy of life is in all of us,” said Bodow. “We may not realize it and it needs to be brought out. You need to accept the fact that there are joys in your life.”One of his most active students is 98-year-old Pauline Hayes.“Some of those words are misspelled and you’re challenged to find them,” said Hayes. “I love doing Joys of Life.”Hayes attends every session and credits the class for keeping her sharp. When we asked her about the secret to life she replied, “keeping positive and keeping active.”Bodow says the program was built on his own experience after spending two months in a coma.“I lost all my memory, all my muscle mass. I had to learn how to walk again,” said Bodow.He’s made an incredible comeback while helping others along the way.“This is never about me,” said Bodow. “It’s making the other people happy, giving them a sense of a full life.”Through the challenges of COVID-19, Joys of Life is touching the lives of residents and staff like never before.Bodow has a collection of puzzles and games on his website. You can check them out here. 1837

SAN DIEGO (KGTV) — The Department of Defense has awarded a San Diego biotech company up to million to help develop a next-generation drug to fight COVID-19.Sorrento Therapeutics calls the drug a “rapid countermeasure” against the disease, one that might serve as a vaccine substitute in certain populations or a critical stopgap tool if the virus mutates.“With this, we have a new platform potentially that can respond very quickly to any type of emerging threat,” said CEO Dr. Henry Ji.Sorrento is trying to become the first company to develop an approved DNA-encoded monoclonal antibody treatment. The approach is similar to the experimental monoclonal antibody treatment used on President Trump, but Sorrento’s concept is a more advanced version that offers several benefits.Sorrento’s drug is designed to be used as either a treatment in infected patients or a fast-forming layer of defense in healthy people. The company said its solution should be cheaper and easier to deploy than existing monoclonal antibodies, while offering vaccine-like protective effects that last for several months rather than just two or three weeks.Antibodies are one of the body’s key defense mechanisms. They seek out pathogens and bind to them, marking the invader for destruction like ground troops marking an enemy base for an airstrike. In some cases, antibodies can even neutralize an invader themselves by blocking its method of entry into cells.Monoclonal antibodies are antibodies designed by scientists to neutralize a pathogen. They are hand-picked, genetically modified super antibodies that are cloned in labs.However, the process of growing these super soldiers in the lab is difficult, transporting them requires a cold chain, and as a result, monoclonal antibodies are among the most expensive drugs in the world.Instead of giving people an infusion of pre-made antibodies, Sorrento’s idea is to give people a shot of DNA that instructs some of their cells to churn out perfectly pre-designed antibodies.“It's much easier to make enough DNA to treat a large number of people than it is to make enough protein to treat a large number of people. That’s just a fact about manufacturing,” said Dr. Robert Allen, Sorrento’s chief scientific officer on the project.Dr. Allen said the company is hopeful the drug will induce cells to make protective antibodies for six months or more.This DNA approach to an antibody treatment has never been approved for any disease but other companies are working on their own versions of it. Another biotech with ties to San Diego, Inovio Pharmaceuticals, became the first company to test this approach in humans in 2019 for a drug targeting the Zika virus.Sorrento’s approach is similar to the way DNA vaccines work, but it cuts out intermediary steps and jumpstarts the production of antibodies, rather than leaving the production of antibodies up to the body’s immune system. The result is that protective antibodies can start circulating in days after injection rather than weeks, the company said.“What this is capable of doing is it bypasses the need for the immune system,” said Dr. Mark Brunswick, Sorrento’s senior vice president for regulatory affairs.The drug is unlikely to replace a vaccine in most situations because vaccines can produce other defense mechanisms like T-cells that work in conjunction with antibodies. But the drug might work better than a vaccine for the elderly and others with weakened immune systems who are unable to produce a robust number of antibodies on their own, Brunswick said.Still, the company still has a lot of pre-clinical work and testing to go. Sorrento is hoping to have the drug ready for human trials in four to six months.By then, vaccines from Pfizer and Moderna will likely be widely available, but Dr. Ji said the world needs to prepare for the possibility this virus will mutate.“When you vaccinate hundreds of millions, potentially billions of people, the virus is under tremendous evolution pressure,” he said. “It will escape. It’s guaranteed that the virus is going to mutate and escape all of the vaccines we’re trying to create.”If it does, he said Sorrento will be ready to rapidly deploy its DNA-based countermeasure. 4223

SAN DIEGO (KGTV) - The Community Resource Center, a non-profit dedicated to helping families in need, was able to overcome the COVID-19 pandemic and deliver holiday happiness to North County families.Every year, the CRC does their annual "Holiday Baskets" program, where families in need get a shopping spree-style day at the Del Mar Fairgrounds to get food, toys, clothing, and more for the holidays.But in 2020, the pandemic made the annual shopping spree impossible because of state and county health guidelines.So the CRC changed things up a bit, turning the event into a drive-thru.Now, instead of walking through a shopping area and picking out items, families will drive through the fairgrounds and have things handed to them in their cars."We'll have a pre-made box of food for each family, we'll have pre-made boxes of blankets for each family, and a pre-made box with family gifts," says CRC CEO John Van Cleef. "So the ability to choose gifts has changed this year, but we'll be providing puzzles, board games, and other family-based gifts."Because of the changes, the CRC could only assist 1,100 families, which is down from their usual 1,600.It may have been even fewer if not for the help of a 15-year old girl."There's always a way that we can help each other out," says Lucie Babcock, who has been volunteering with the CRC since she was 9.For the past five years, Lucie has held bake sales or lemonade stands to raise money for the CRC. She then uses the money to buy toys and gifts for the families.Because of the Pandemic, she couldn't do her usual fundraising.Instead, Lucie wrote letters to family and friends asking for donations. She raised 0."Even if it seems like maybe you don't have the connections to make a difference, there's always a way," she says.Van Cleef says people like Lucie inspire him to keep helping others.The Holiday Baskets event is Saturday, Dec. 4, but families must pre-register to participate. 1952

SAN DIEGO (KGTV) -- The City of San Diego is set to open a third homeless storage facility on Monday. The facility will be similar to the locations in downtown and Logan Heights, allowing homeless to safely store their personal belongings while trying to get back on their feet. The new location is located on 54th and Lea Street in El Cerrito. It will be operated by Mental Health Systems (MHS), a nonprofit that also operates the Logan Heights location. The organization helps people that are affected by substance abuse and behavioral health disorders. With the addition of this third location, the city now has storage space for over 1,400 people. 10News spoke to homeowners near the new storage location and neighbors had mixed reactions. Some worried the facility would attract more homeless to the area and others worried about people leaving trash behind in their neighborhoods. Some neighbors told 10News they welcome the facility and hope this will help people get back on their feet. The facility opens at 10:30 a.m. on Monday. 1047

SAN DIEGO (KGTV) - Summer vacation. A time for kids to cut loose and enjoy weeks of freedom. And as studies have shown, to forget chunks of what they learned the year before. Even shorter breaks can erase some lessons.A special program at San Diego Unified is helping keep kids stay sharp and excited about learning all year round, even during breaks. It's about making learning a fun, family affair.In a classroom at Rosa Parks Elementary School in City Heights, 7-year-old students Melody and Isabella are getting some one-on-one attention with their lessons. The teachers in this case are Melody's grandmother and Isabella's mom."Everyday they have to read. Everyday they have homework to do," said Anna Gonzalez. She and Maria Theresa Jaume are among a growing number of parents and guardians getting more involved with their kid's education through the "Family Engagement Department" at San Diego Unified."So, I now know how to ask her questions," says Gonzalez, "How to engage her with the reading and things like that.""It solidifies the bond right," says Family Engagement Program manager Pamela King, "It shows kids that education is important." King says the program was established in 2016, inviting families to become partners in their kid's education with tips on how to do it."You're reading a fiction book. You're learning about the characters but what are characters thinking? What's motivating the character? So, going a little deeper."Organizers say it's about connecting with a child's curious nature. Making reading as fun as playtime, or as close as possible.You can find out more about the family engagement program here. 1651