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As we're all focused on the current rollout of the COVID-19 vaccine, a technology known as thin-film freezing is getting a lot of attention. It's groundbreaking and could change the way we administer drugs or use medicine in general.You've probably heard about the need to keep the COVID-19 vaccine cold. It has to be so cold, in fact, that the shipment and transport are challenging. Well, what if that vaccine could be turned into powder?“What we’ve most recently been working on is the elimination of cold chain by storing as a powder, a dry powder where the drug is much more stable than if it was stored as a liquid or as a frozen liquid,” said co-inventor Dr. Robert Williams.Williams said it would eliminate the need for extreme cold storage and transport. The technology isn't new. He got a research grant and came up with it about 15 years ago.Williams, who is also a pharmacy professor at the University of Texas in Austin, said they were working on the technology and its multiple uses when the pandemic hit. And all of a sudden, they got a lot of attention.“We have published over 70 papers on the technology and using it for different products- it’s quite a mature process," Williams said. "We developed it because with other vaccines, the majority of the vaccine cost is in wastage because of this cold chain issue, so we published several key papers where we showed our thin-film freezing technology would protect vaccines - and you wouldn’t need cold chain storage.”Glenn Mattes, President, and CEO of TFF Pharmaceuticals added that the powders can be converted to topical preparations and they are currently working with the US Army to take some of the preparations and would then administer them directly through the eye.TFF is launching thin-film freezing into development through the FDA process. “I use the term ubiquitous because it is and disruptive because it is,” Mattes said. He added that they've explored their technology in the cannabinoid realm. But, as for the COVID vaccine, they're aiming for a second-generation usage.“To truly eradicate the pandemic, you have to have a global response," Mattes said. "The companies we’ve been speaking to certainly recognize the broad utilization of the technology but the application to the developing world, rural area, remote areas, where you can take a powder and inhale it or take the powder and reconstitute it has tremendous potential."Experts say it is only just the beginning as they launch their technology into a new world. 2511
As wildfires rage in California, emotions are heating up.“People are not getting along,” said Boulder Creek, California, local Alex.In the Santa Cruz mountains, people are stocking up on gas but running out of patience.“The whole valley was closed,” Alex said. “Closed man!”At the local grocery store, workers are counting every single cent after being shut down for two weeks due to fire concerns.“We definitely have stocked up on our gallon waters,” said Vanessa Russo, owner of Wild Roots Market in Boulder Creek.Russo says wildfires during the pandemic have drastically cut into profits and are now weighing on people’s wallets and their well-being.“A lot of our customers are having to deal with refrigeration issues and slowly having evacuations be lifted,” she said.With thousands of homes destroyed during these fires and many businesses already suffering due to COVID-19 concerns, rebuilding could come at a cost never seen before.“The 2020 fire could be even more catastrophic than say the 2018, which was I think was billion,” said Janet Ruiz with the Insurance Information Institute.Ruiz says the California fires could impact areas across the country.“Agriculture, you talk about the wine industry,” she said. “Beef, the pork, all those could be affected by catastrophe.”The economic impacts of these fires stretch from the mountains, all the way to the ocean“So, the time when our businesses need funding from us, we don’t have it to give,” said Bonnie Lipsco-mb, director of economic development for the City of Santa Cruz.Fire displaced Lipscomb’s family and they’re now living in a trailer.”Despite the new digs, Lipscomb is still focused on helping her community during these unprecedented times.“The impact is really catastrophic,” she said. “I don’t think we’ve seen this since the earthquake and maybe not even then.”With much of the city’s budget funded through sales and property taxes, areas of income that were already suffering before the fires, city leaders are now seeking support from state and federal government agencies.“We’re working on long-term recovery, but at the same time, it's day by day,” Lipscomb said.That road to economic recovery, however, will be long and costly. 2221

AURORA, Colo – A man is giving a family a piece of their hero back after finding World War II dog tags on a job site he was working on.“They’re going into the mail today,” Michael Huber said in his office, surrounding by old photos and knick-knacks packed away in a box.Huber has all the respect in the world for a man he’s never met, but came across his name in the dirt.“Well, I was excavating on my jobsite,” Huber said. “I was getting rid of some trash and debris from years ago, and I pulled out a bucket and there was something shiny sticking out. I saw what it was and it was dog tags.”The name Gail Sheldon was engraved on the tags.“It said he got his shot in 1943,” Huber said. “Amazing. World War II dog tags.”Doing a little research, Huber found out who Sheldon was.“He was a captain and flew B-24 bomber planes,” Huber said. “He had several missions over Berlin, and he flew during D-Day. He was even shot down one time.”Huber was able to get into contact with Sheldon’s family after a couple of months. He found out from the family Sheldon died in 1990.Huber is now sending back the dog tags along with Sheldon’s pilot wings that he found with the tags. He packs up a box filled with old coke bottles and old squirt guns from that time that he found on the job site.“It could possibly be his family’s,” Huber said.Huber, who has also served in the U.S. Army, said he deeply respects Sheldon. Which is why it's important to send this memento back to the family.“Dog tags to me is part of a person’s being,” Huber said. “It’s a symbol of them giving up everything.” 1584
Attorneys for the suspect in a deadly shooting at a Kentucky grocery store entered not guilty pleas on his behalf during his arraignment Friday.Gregory Bush, a 51-year-old white man, is accused of fatally shooting two African-Americans in the Kroger grocery store in Jeffersontown, and in the parking lot. Authorities have said the shootings appear to be racially motivated.Bush has been charged with two counts of murder, one count of attempted murder, and two counts of wanton endangerment for the October 24 shooting."It's particularly in times of loss and tragedy that our Constitution and our laws can be particularly tested, so Mr. Bush, of course, has rights to due process and a fair trial that we all are honored to have," public defender Angie Ellerman told CNN affiliate WAVE. 795
ATLANTA (AP) — NASA astronaut Kate Rubins told The Associated Press on Friday that she plans to cast her next vote from space – more than 200 miles above Earth. Rubins and two cosmonauts are in Star City, Russia, just outside Moscow. She's preparing for a mid-October launch and a six-month stay at the International Space Station.Texas law allows U.S. astronauts to vote from space using a secure electronic ballot. Mission Control in Houston forwards the ballot to the space station, which Rubins then emails to the county clerk. 539
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