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As the COVID-19 pandemic progresses, researchers say it is important to track how the coronavirus mutates because it could affect the efficacy of a vaccine.Like all living cells, viruses evolve their chemical make-up changes. In viruses like the flu, that happens frequently, which is why every year there is a new vaccine to treat whatever strain is expected to circulate. With COVID-19, however, those mutations happen much slower, according to research out of Arizona State University.“One of the things we’re still keeping an eye on is the evolution of this virus because that virus is still around in the community,” said Dr. Efrem Lim, an assistant professor at ASU. “Everyone is coming in blind to this. This is a novel virus. This isn’t something we have seen before.”In March, Arizona State University played host to our country’s fourth COVID-19 case. As soon as it was detected, Dr. Lim started studying how the virus mutates and sent his findings to the World Health Organization. It's something that still continues to this day.“This virus, overall, mutates pretty slowly, which is a good thing,” said Dr. Lim. “However, we can have instances where the virus can have very large, dramatic, mutations, such as deletions in the genome.”While rare, Dr. Lim says those mutations can be significant as it changes how the virus acts inside the body.Currently, scientists are focusing much of their efforts on identifying ways to eliminate the function of the spike protein in COVID-19, as it is the way the virus binds to our cells and infects them (spike proteins are the stalks that protrude from the center of the virus that make it so recognizable).“It is very good news that the virus is not changing rapidly,” said ASU virologist Dr. Brenda Hogue. “We will have to see over time, as the virus continues to circulate, as we put a vaccine into play, whether or not there will be any issues.”Dr. Lim says right now there does not appear to be any issues because the virus mutates slowly, but he adds it could adapt to a vaccine once one begins to circulate.He says more testing needs to be done to determine that, however. 2140
At least 257 people have been killed in a military plane crash near Algeria's capital, Algiers, state media reports.The aircraft crashed near the Boufarik air base, between Algiers and the city of Bilda. Ten of those killed were the plane crew, according to state-run Radio Algerie.It was not immediately clear whether there were any survivors.TV station Ennahar showed images of smoke rising from the plane's fuselage, tilted to one side, with part of the aircraft sticking out above olive trees. Dozens of bodies were seen in numbered bags as paramedics and firefighters worked at the crash site.The-CNN-Wire 618
Atal Bihari Vajpayee, India's tenth prime minister, died Thursday in New Delhi at the age of 93.A statement released by the hospital treating him said "his condition deteriorated over the last 36 hours and he was put on life support systems. Despite the best of efforts, we have lost him today.""India grieves the demise of our beloved Atal Ji. His passing away marks the end of an era. He lived for the nation and served it assiduously for decades. My thoughts are with his family, BJP Karyakartas and millions of admirers in this hour of sadness. Om Shanti," tweeted Indian Prime Minister Narendra Modi.Celebrity deaths of 2018: Remembering those we've lost this yearVajpayee was prime minister briefly in 1996 and 1998 before eventually serving a full term as premier from 1999 to 2004. He had been admitted in June to the All India institute of Medical Sciences in the capital, suffering from a urinary tract infection and chest congestion. His condition worsened, eventually becoming fatal.Vajpayee never married. He is survived by his adopted daughter, Namita.During his political career, Vajpayee's name became synonymous in India with the rise of the ruling Bhartiya Janata Party (BJP), which he helped found in the 1980s. His ascent to the premiership signaled the renewal of the party, which had grown to become the main opposition to the Indian National Congress before eventually overtaking that party.Vajpayee's tenure as India's leader was marked by significant developments in the country's defense policy, and he oversaw India joining the world's nuclear weapons club in 1998.Facing heavy criticism at home and abroad over India's nuclear ambitions, Vajpayee defied the threat of economic sanctions, telling parliament that "we have never made a decision after coming under international pressure and we will never do so in the future."Born in December 1924, Vajpayee grew up in the central Indian state of Madhya Pradesh and was one of the founders of the Janata Party, a splinter group of which became the modern BJP. During his youth he was briefly a member of the right wing Hindu nationalist group Rashtriya Swayamsevak Sangh (RSS), and was arrested along with his brother in 1942 for protesting against British rule.Vajpayee won his first election to parliament in 1957, a decade after independence. He would go on to hold that role for nine terms.Though he was elected prime minister three times, Vajpayee only competed an entire term once. His first government collapsed in less than three weeks in 1996, and while he took power again in 1998, this only last 13 months before a disagreement within the ruling coalition sparked new elections.Vajpayee was returned to the premiership in 1999 after his BJP-led coalition secured a comfortable majority in the wake of a two-month long war with Pakistan over control of Kashmir.In late 2001, India's parliament was hit by a terrorist attack which Delhi blamed on Pakistan, while in 2002, riots in Gujarat claimed the lives of hundreds of Muslims.Despite India's contentious seven-decade relationship with Pakistan, Vajpayee is credited with being the only Indian leader to make significant progress in peace talks with the country's nuclear-armed neighbor.Even as he pursued a nuclear agreement with Pakistan, Vajpayee remained a defiant defender of India's security policy, an approach which eventually paid off. Economic sanctions imposed after the country's first atomic test were finally lifted in 2000 when Bill Clinton visited the country, the first US President to do so in 22 years. Vajpayee also improved relations with Beijing, officially recognizing Tibet as part of China.A talented orator, one of Vajpayee's most remembered speeches was a hugely critical one, bemoaning India's lack of progress after five decades of independence."Our country is counted amongst the poorest in the world," he said. "We can't make primary education a necessity. We are still expecting that girls should be educated. The birth of a girl in this country is still a curse."More than 15 years after the speech was given, however, the country continues to be plagued by many of the same problems.Away from politics, Vajpayee is also remembered as an accomplished poet, releasing many books over the years filled with Hindi poems.Just as his fellow BJP prime minister, Narendra Modi, has focused on promoting "brand India," Vajpayee saw great success in building his country's reputation around the world. He addressed the United Nations General Assembly in 2001 and a joint session of the US Congress in 2000. Bilateral agreements signed between his government and Moscow set the stage for annual summits which continue to this day, as does the close relationship with China he cultivated."At a time when an external stimulus has motivated us to unite against terrorism and for security, let us summon an equally strong inner resolve for development and poverty alleviation," Vajpayee said in his speech to the UN. "They are just as crucial for a global order at peace with itself."The-CNN-Wire 5061
As part of regular protocols, Secretary @stevenmnuchin1 has been tested daily for COVID-19. He tested negative for COVID-19 this morning and will continue to be tested daily.— Monica Crowley (@TreasurySpox) October 2, 2020 230
As September is NICU Awareness Month, parents of NICU babies are working to serve as a voice for families who are trying to navigate the overwhelming and often terrifying experience of watching your baby in a neonatal intensive care unit, especially during a pandemic.When Andi Petito was 21 weeks pregnant, she went in for a simple and common anatomy scan of her baby.“When she got really quiet and excused herself,” Petito said about a routine appointment. The technician who performed the ultrasound returned with the doctor who said there were some major problems, Petito was sent to the hospital where she would remain on bed rest until she went into labor. Petito gave birth to River at 24 weeks, weighing 1 pound, 7 ounces. River was transferred to the NICU.“They warn you it's a roller coaster and they try to prepare you but you’re not really prepared for the ups and downs,” Petito said.That roller coaster is how they describe the NICU.“Terrifying, stressful and, I mean, we lived on edge,” Petito said. “You almost feel paranoid because you’re so worried about her compromised immune system, comprised lungs. Kind of like we’re all living now, but no one else is joining you in it.”Neonatologist Dr. Melinda Elliott said no one expects, prepares or plans for a NICU stay.“Nobody plans to meet me, nobody plans to meet the doctor who specializes in sick babies,” Elliott said.She said parents should not focus on all of the machines and equipment that surround your newborn.“The best thing you can do is turn the other way and focus on your baby,” Elliott said. “Just look at your baby because that baby is your baby no matter how small or how sick. You’re the only parent that baby has.”Elliott said the pandemic has stripped the visitor policy. Usually, there's only one parent allowed in at a time. While that's hard for already stressed families to manage, she reminds parents to focus on the importance of nutrition and to continue to advocate for your baby.“Probably the biggest piece of advice is just ask questions, keep asking,” Elliott said. “If you don’t get an answer you like, ask again and find somebody else to ask. You deserve to understand what’s going on with your baby:”Now, after 129 days in the NICU, that once tiny little baby is 3 years old, and likes to discuss her favorite color, pink, and all things Paw Patrol. Petito said she got through the NICU by doing her own research, being her own advocate, fighting for what her baby needs and by being honest with herself.“It’s OK to fall apart sometimes,” Petito said. “Parenthood is not what you envision when your child is not able to come home with you and everything has been blown up and so it’s okay if you need to cry and fall apart and pick yourself back up and go to the NICU.”The Petitos have now given River a sibling. Fern is happy and healthy and didn't need the NICU. And while it was never an easy roller coaster ride, they say it made River the strongest little fighter they know. 2987