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Immunotherapy has gained ground against a stubborn opponent: ovarian cancer. A personalized cancer vaccine is safe and may lengthen the lives of ovarian cancer patients, a small clinical trial found.The research, published Wednesday in the journal Science Translational Medicine, showed "significantly higher" overall survival at two years among patients who received the vaccine, compared with patients who did not.Ovarian cancer is a "silent killer" because often it goes unnoticed until it is diagnosed at a late stage. Treated with surgery followed by chemotherapy, most patients -- 85% -- relapse and ultimately develop resistance to the chemo. At this point, they run out of treatment options.Still, scientists are hopeful based on the fact that a subset of patients shows an immune response to their cancer. Generally, these patients have better survival rates than those whose immune systems don't react in the same way.A vaccine, then, might be able to trigger and boost the immune system and increase the survival rates of patients, said Dr. Lana Kandalaft, senior author of the new study and an adjunct assistant professor at the University of Pennsylvania Perelman School of Medicine. 1210
Immunotherapy has gained ground against a stubborn opponent: ovarian cancer. A personalized cancer vaccine is safe and may lengthen the lives of ovarian cancer patients, a small clinical trial found.The research, published Wednesday in the journal Science Translational Medicine, showed "significantly higher" overall survival at two years among patients who received the vaccine, compared with patients who did not.Ovarian cancer is a "silent killer" because often it goes unnoticed until it is diagnosed at a late stage. Treated with surgery followed by chemotherapy, most patients -- 85% -- relapse and ultimately develop resistance to the chemo. At this point, they run out of treatment options.Still, scientists are hopeful based on the fact that a subset of patients shows an immune response to their cancer. Generally, these patients have better survival rates than those whose immune systems don't react in the same way.A vaccine, then, might be able to trigger and boost the immune system and increase the survival rates of patients, said Dr. Lana Kandalaft, senior author of the new study and an adjunct assistant professor at the University of Pennsylvania Perelman School of Medicine. 1210
In advance of hurricane season, Florida Power and Light is reviewing plans to make sure power is restored quickly after a storm. This week the company is holding its annual storm drill, simulating a Category 3 hurricane. During the drill, the company says it is incorporating lessons learned from Hurricane Irma, which knocked out power to 6.7 million electrical customers, according to the U.S. Energy Information Administration (EIA).EIA reports the rate of electric service restoration following Hurricane Irma was faster than Hurricane Wilma in 2005. Five days after Irma’s landfall, the share of customers without power had fallen from a peak of 64 percent down to 18 percent -- a recovery rate of about 9 percent of customers per day.Power outages during Wilma declined from 36 percent of customers to 16 percent by the fifth day after landfall. This is an average recovery rate of about 4 percent of customers per day. FPL credits the improvement to money spent on infrastructure improvements. Since 2006, more than 860 main power lines were hardened; within the next five to seven years FPL wants to harden all of them.Strengthened power lines perform approximately 40 percent better than non-strengthened lines, FPL said.This year, FPL plans to undertake the following additional initiatives to improve the reliabilityof service: 1416
House lawmakers on Wednesday overwhelmingly passed legislation expanding veterans' access to private care at taxpayer expense, a campaign promise of President Donald Trump, and adding more money to the "Choice program" weeks before VA officials said it could run out of money.The billion plan that passed 347-70 Wednesday includes .2 billion for the VA Choice program that funds private care. VA officials have warned that the program could run out of money as early as the end of the month, disrupting care for patients.Hours before the House vote, Trump weighed in, urging lawmakers to back the bill."House votes today on Choice/MISSION Act," Trump tweeted on Wednesday. "Who will stand with our Great Vets, caregivers, and Veterans Service Organizations? Must get Choice passed by Memorial Day!"A similar plan almost became law as part of the omnibus spending bill in March, but was blocked by some Democrats concerned about privatization of services for the nation's veterans.There has been a long simmering debate about the extent to which veterans obtain care in the private sector. Many veterans groups say they don't want to see too many resources shifted outside the VA, a move they say would fundamentally bleed the health system dry.The legislation is moving forward in Congress as the sprawling agency remains without a permanent leader after Trump ousted former Secretary David Shulkin and the nomination of Rear Adm. Ronny Jackson, the White House physician, unraveled amid allegations about his professional conduct.It would also launch a review of VA facilities with an eye toward closing under-performing institutions and would expand a VA caregivers program to cover the families of pre-9/11 veterans. 1733
In a joint press release on Thursday, a group of Trump administration officials called the 2020 election "the most secure in American history," directly contradicting the President.In their statement, the members of the Election Infrastructure Government Coordinating Council (GCC) Executive Committee added that "there is no evidence that any voting system deleted or lost votes, changed votes, or was in any way compromised."“While we know there are many unfounded claims and opportunities for misinformation about the process of our elections, we can assure you we have the utmost confidence in the security and integrity of our elections, and you should too," the statement read, in part. "When you have questions, turn to elections officials as trusted voices as they administer elections.”The statement added that all states that use computerized voting systems also have paper records of each vote, meaning states can further verify results if needed.Ten members of the GCC signed the statement.The press release was issued by the Cybersecurity & Infrastructure Security Agency, an agency within the Department of Homeland Security. The GCC is a coalition of federal government agencies, as well as state election offices and secretaries of state with the goal of providing security and "resilience strategies" for elections of all levels across the country.Their statement directly contradicts claims made by President Donald Trump, who has not yet conceded to President-elect Joe Biden. Trump has claimed without evidence that the 2020 presidential election was beset by widespread voter fraud. The Trump campaign has filed several lawsuits in key battleground states to contest the results of the election, but the suits have not yet fundamentally altered the state of the race. 1800