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As the coronavirus pandemic continues, doctors are learning more about the damage having Covid-19 can do to the body. Two separate studies published recently indicate the coronavirus can harm other organs in the body, including the heart.One of the studies looked at 100 patients in Germany who recently recovered from Covid-19 and found 60 percent of participants had inflammation in the heart. The study used MRI scans to monitor the inflammation, and was published in JAMA Cardiology.The majority of the patients in this study, 67 of them, recovered from the coronavirus at home with severity ranging from asymptomatic to moderate. It compared the MRIs of coronavirus survivors to scans from healthy volunteers.The data showed there was some sort of heart involvement in those who had coronavirus, whether or not they had preexisting conditions or any heart-related symptoms during recovery.“Our findings reveal that significant cardiac involvement occurs independently of the severity of original presentation and persists beyond the period of acute presentation, with no significant trend toward reduction of imaging or serological findings during the recovery period. Our findings may provide an indication of potentially considerable burden of inflammatory disease in large and growing parts of the population and urgently require confirmation in a larger cohort,” the researchers noted in conclusion.A second study, also published in JAMA Cardiology, found coronavirus could be found in the heart tissue of patients who died.The study looked at data from 39 autopsy cases in Germany in early April. The patients were aged 78 to 89, had tested positive for Covid-19 and there were results of heart tissue analysis in their autopsies.In 16 of the 39 cases, there was a large “virus load” of coronavirus found in the heart tissue, another eight had a coronavirus presence in the tissue.The sample of autopsy cases was small and the "elderly age of the patients might have influenced the results," the researchers wrote. More research is needed whether similar findings would emerge among a younger group of patients."Taken together the studies support that SARS-CoV-2 does not have to cause clinical myocarditis in order to find the virus in large numbers and the inflammatory response in myocardial tissue. In other words, one can have no or mild symptoms of heart involvement in order to actually cause damage," said Dr. Dave Montgomery, who was not involved in the studies, in a statement to CNN.Dr. Clyde Yancy of Northwestern University Feinberg School of Medicine and Dr. Gregg Fonarow of the University of California, Los Angeles, co-authored an editorial that accompanied the two new studies in the journal JAMA Cardiology called ‘Coronavirus Disease 2019 (COVID-19) and the Heart—Is Heart Failure the Next Chapter?”“We see the plot thickening and we are inclined to raise a new and very evident concern that cardiomyopathy and heart failure related to COVID-19 may potentially evolve as the natural history of this infection becomes clearer,” they write. 3076
As the coronavirus continues to wreak havoc in our lives, many people are looking for ways to manage the stress that has come with it.Drink maker PepsiCo is adding to your options of stress relief aid.On Monday, the company unveiled Driftwell, a new drink designed to ease stress and help you relax.PepsiCo says the drink is loaded with an amino acid that helps with calmness, improves focus, and helps with sleep.You'll be able to get Driftwell online later this year and in stores early next year. 507

At Wednesday night’s Vice Presidential Debate in Salt Lake City, there will be a ticket waiting for Tupac Shakur.The Trump campaign says it has reserved a ticket for the singer because Senator Kamala Harris, the Democratic candidate for vice president, recently said Tupac was her favorite rapper alive.Tupac Shakur died in a drive-by shooting in 1996.Trump’s senior campaign advisor, Jason Miller, confirmed the ticket for Tupac during a press call ahead of Wednesday’s debate, according to media reports.“I’m personally more of a Biggie (The Notorious B.I.G.) fan,” Miller said according to The Hill, and if he is still alive, “we’ll have a ticket for Tupac.”It was also confirmed by the Trump campaign’s communications director Tim Murtaugh. 752
As we're all focused on the current rollout of the COVID-19 vaccine, a technology known as thin-film freezing is getting a lot of attention. It's groundbreaking and could change the way we administer drugs or use medicine in general.You've probably heard about the need to keep the COVID-19 vaccine cold. It has to be so cold, in fact, that the shipment and transport are challenging. Well, what if that vaccine could be turned into powder?“What we’ve most recently been working on is the elimination of cold chain by storing as a powder, a dry powder where the drug is much more stable than if it was stored as a liquid or as a frozen liquid,” said co-inventor Dr. Robert Williams.Williams said it would eliminate the need for extreme cold storage and transport. The technology isn't new. He got a research grant and came up with it about 15 years ago.Williams, who is also a pharmacy professor at the University of Texas in Austin, said they were working on the technology and its multiple uses when the pandemic hit. And all of a sudden, they got a lot of attention.“We have published over 70 papers on the technology and using it for different products- it’s quite a mature process," Williams said. "We developed it because with other vaccines, the majority of the vaccine cost is in wastage because of this cold chain issue, so we published several key papers where we showed our thin-film freezing technology would protect vaccines - and you wouldn’t need cold chain storage.”Glenn Mattes, President, and CEO of TFF Pharmaceuticals added that the powders can be converted to topical preparations and they are currently working with the US Army to take some of the preparations and would then administer them directly through the eye.TFF is launching thin-film freezing into development through the FDA process. “I use the term ubiquitous because it is and disruptive because it is,” Mattes said. He added that they've explored their technology in the cannabinoid realm. But, as for the COVID vaccine, they're aiming for a second-generation usage.“To truly eradicate the pandemic, you have to have a global response," Mattes said. "The companies we’ve been speaking to certainly recognize the broad utilization of the technology but the application to the developing world, rural area, remote areas, where you can take a powder and inhale it or take the powder and reconstitute it has tremendous potential."Experts say it is only just the beginning as they launch their technology into a new world. 2511
As the holidays approach, many people are wondering how to safely celebrate. The CDC has urged Americans not to travel for Thanksgiving, and offering guidance for those who still want to go somewhere. Health officials weighed in on whether you need to quarantine before you visit family for the holidays."My own family, we usually have 100 relatives every year at Thanksgiving. Now, clearly, that’s not going to be happening this year. It’s going to be on Zoom for the big family, but I think there are ways that you can celebrate with your smaller family and get together safely, but it's going to take some work and some planning," said Dr. Tanya Altmann, a pediatrician and spokesperson for the American Academy of Pediatrics.Dr. Altmann says there are a number of steps people can take to protect themselves from getting COVID-19 this holiday season. Ideally, everyone would quarantine for two weeks before and after a get-together. Some families may think about switching their kids to remote learning if they are not already doing it."I don’t think its drastic. If you want to get together with elderly grandparents for Thanksgiving, I think keeping your kids home from school for a week and then testing them on day five to seven, assuming everybody is asymptomatic, can make a lot of sense. Again, I would still try to keep them a little distanced from the grandparents," said Dr. Altmann.But what if you can't switch your kids to remote learning? Dr. Altmann says then it won't be a true quarantine, but most schools that are in-person right now are doing everything right."They're masking, they’re distancing, they’re sanitizing and disinfecting, they’re hand washing. So, what we’re seeing is most kids are not catching COVID-19 in the school classroom during the school day, they're catching it at after-school activities, they're catching it on the weekends when they're gathering with friends or their families or doing things that maybe they shouldn’t necessarily be doing," said Dr. Altmann.So, how long should you quarantine last? For medical professionals, a quarantine usually refers to a person who's potentially been exposed but is not showing symptoms. It's a waiting period to help determine infection."I think really the best guidance is to wait that 14-day quarantine period to have some degree of confidence that you’re not going to become infected," said Dr. Beth Thielen, an Assistant Professor of Pediatrics at the University of Minnesota Medical School and an infectious disease physician. Dr. Thielen says, to be extra careful, you could also test yourself seven days into your two-week quarantine."A testing in between without symptoms is somewhat helpful because we also know there are a certain percentage of people who will develop asymptomatic infections and, in particular, this is probably important for children," said Dr. Thielen.However, testing rules and access varies in each state, so it's best to reach out to your local health official or doctor to find out about availability and turnaround times for results."So, I think for some, where now I'm hearing people are waiting days after a test, and so if you're planning to get tested before a trip and it's going to take four to five days to turnaround the test, that could be the entirety of your trip," said Dr. Thielen.Health officials advise erring on the side of caution, especially if you're planning on visiting elderly family members."I think the most important thing is to be really aware of that it's not just your family. 'Oh, we don't want to catch COVID, we might get sick' but that you could spread it to others who are even more vulnerable," said Dr. Altmann.Experts say to take the highest precautions to create the least amount of risk. 3756
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