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A final analysis of a COVID-19 vaccine candidate produced by Pfizer and BioNTech shows that the drug is 95% effective in preventing the coronavirus, and the companies say they hope to apply for Emergency Use Authorization within "days," the company reported Wednesday.The announcement is an improvement from an initial analysis released by the company just over a week ago that showed the drug to be 90% effective. Those results were released when it had been confirmed that 94 participants in the trial who received a shot had contracted COVID-19, and only 10% of those participants who contracted the virus had actually received the vaccine. Updated information now shows that 170 people who participated in the trial have contracted COVID-19, which crosses the threshold for final analysis. Of those participants, 162 received a placebo shot. Of the 20,000 participants who received the vaccine, just one has developed a severe case of COVID-19. The other seven people who received the vaccine and caught the virus are only experiencing mild symptoms.Pfizer also added that the vaccine has proven to be 94% efficient in older people — a welcome sign, given that the virus tends to present more severe symptoms in elderly patients.Pfizer's trial included about 40,000 participants, half of which received the vaccine, and the other half which received the placebo. The vaccine requires two shots, which need to be taken 28 days apart.The company added that there have been no safety concerns with the vaccine. In a randomized survey of 8,000 participants, only 2% reported suffering severe fatigue, and only 4% reported suffering severe headaches. Those who say they suffered side effects only experienced them briefly after vaccination.Wednesday's announcement means Pfizer is on track to shatter records for vaccine development, a process that typically takes several years.Pfizer and BioNTech already have their vaccine candidate in production, meaning it will be ready for distribution as soon as the Food and Drug Administration grants Emergency Use Authorization.Pfizer's announcement comes days after an initial analysis of a Moderna-produced vaccine was also shown to be 95% effective. Several other companies also have a COVID-19 vaccine in the works, something that health officials say is important for logistics and safety. 2347
A Buckeye, Arizona man on active duty with the United States Air Force was booked into jail this week on second-degree murder charges after the death of his infant. On June 13, 2017, Phoenix Police responded to a report of a 3-month-old boy who was pronounced dead at Phoenix Children's Hospital. According to police paperwork, 25-year-old John Centano, the child's father, said he was home alone with the baby for about 20 minutes before he found him unresponsive on the master bed. He said it was about a minute or two after he left the child alone, face-down on the bed, to quickly grab shower items from the hallway bathroom. According to staff at the emergency room, Centano reportedly said he took a shower and returned to find the child unresponsive. An autopsy was performed on the child and his death was ruled a homicide due to complications with head trauma and other internal injuries. Investigators found evidence at the home suggesting that no shower items were retrieved from the hallway bathroom. Police say Centano made several inconsistent statements, including blaming their large dogs for the child's injuries. Centano was arrested on Tuesday and booked into jail on felony counts of second-degree murder and child abuse. Police documents show that Centano was employed with the United States Air Force on active duty. 1422

A federal judge halted construction of the controversial Keystone XL oil pipeline on Thursday, in a blow to the Trump administration and a win for environmental groups.US District Judge Brian Morris found that the US government's use of a 2014 environmental review to justify issuing a presidential permit for construction of the cross-border pipeline violated the National Environmental Policy Act, the Endangered Species Act and the Administrative Procedure Act, according to the court order issued Thursday."The Court enjoins Federal Defendants and TransCanada from engaging in any activity in furtherance of the construction or operation of Keystone and associated facilities," the court document reads, "until the Department has completed a supplement to the 2014 SEIS (Supplemental Environmental Impact Statement) that complies with the requirements of NEPA and the APA."Environmental groups involved in bringing the 2017 lawsuit celebrated the decision."Keystone XL would be a disaster for the climate and for the people and wildlife of this country," said Jackie Prange, senior attorney at the Natural Resources Defense Council, one of the plaintiffs. "As the court has made clear yet again, the Trump administration's flawed and dangerous proposal should be shelved forever."In March 2017, President Donald Trump's administration issued a permit approving construction of the pipeline, reversing the Obama administration's decision to block the controversial project.The White House has not responded to CNN's request for comment on the judge's order.The permit approval followed years of intense debate over the pipeline amid steadfast opposition from environmental groups.They argued that the pipeline would support the extraction of crude oil from oil sands, a process that pumps more greenhouse gases into the atmosphere than standard crude oil extraction. They also opposed the pipeline because it would run across one of the world's largest underground deposits of fresh water.Native American groups argued the pipeline would cut across their sovereign lands.The-CNN-Wire 2099
A Kentucky high school teacher on Tuesday ousted an incumbent state lawmaker who had a role in passing a controversial pension bill this year that sparked outrage from teachers across the state.Republican voters chose Travis Brenda, a high school math teacher, over House Majority Floor Leader Jonathan Shell, who was first elected in 2012.Brenda bested Shell by a narrow margin of 123 votes In Tuesday's Republican primary for House District 71st, according to unofficial results posted to the Kentucky State Board of Elections.This past spring, Kentucky teachers held rallies at the state Capitol for more funding and to oppose a controversial pension bill, Senate Bill 151, which, among other initiatives, prevents changes to annual cost-of-living adjustments and limits the number of sick days teachers can put toward their retirement.Shell had helped turn SB 151, which had been about sewage services, into a pension overhaul and voted in support of the bill. The bill was quickly passed in the House and the Senate without allowing the public to read it, and then sent to GOP Gov. Matt Bevin to sign the bill on April 11.During the campaign, Brenda used his experience as a teacher to make the point that he's not a politician and he understands the importance of funding education. On Twitter, Brenda was critical of the pension bill and posted pictures from the April 2 teacher protest at the state Capitol.Shell confirmed to CNN he called Brenda Tuesday night to congratulate him. Shell, once considered a rising star in Kentucky Republican politics, said he was grateful for the six years he served and now looks forward to spending more time with his wife and kids.Brenda will go on to face Democratic candidate Mary Renfro in November's general election. 1774
A fashion designer had broken the record for largest afro for a female by three inches. Simone Williams’ hair measures 4 feet 10 inches in circumference, according to Guinness World Records.Williams has been growing her hair out for about 9 years, but she didn’t start wearing an afro with the record in mind. She told Guinness she got perms and straightened her hair in middle school to fit in, and wore her hair straight until college."I chose to transition [to natural hair] around the age of 23. It began because I wanted to save the money spent at the hair salon to help with the costs of moving into my first apartment,” Williams said in a release from Guinness. "The process was very difficult at first since I was accustomed to wearing my hair straight and I didn’t know how to manage my natural hair texture."Williams says it takes about 6 hours for her hair to dry, and she washes it about once a week. “I use a lot of conditioner because it helps detangle my hair. I section my hair into 4 twists while in shower,” she said."When my hair is fully styled and big and voluminous I get a lot of stares, a lot of comments, lots of compliments – I want to think that everything is positive, but there are some people who stare like they have no idea what’s going on or what they’re looking at,” Williams said.Williams said she was inspired by the previous record holder, Aevin Dugas, who held the women’s record for largest afro since 2012 with a circumference of 4 feet 7 inches.Dugas says as her hair has gotten longer, it’s gotten heavier and doesn’t stand out as much. She plans to get some layers cut and hopes to be in the running again for the largest afro."Rocking a natural ‘fro is something that really symbolizes your pride in being Black. And I feel like whenever I wear my hair very big and beautiful, I just feel that pride within me,” Williams said. Adding, “Styling my hair like this is a silent reflection of who I am as a Black woman, it’s dynamic, it’s larger than life, and it’s fun! Sometimes I leave the house and if I have on a plain outfit, my hair will be my biggest accessory.” 2117
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