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SAN DIEGO (KGTV) - Mesa Biotech, based in San Diego, has received FDA approval for its rapid COVID-19 tests that can produce results in about half-an-hour.“Our first kits are going out today to some of the health systems, county health departments, to validate the performance against the existing testing,” said Laura Dullanty, a marketing manager at Mesa Biotech. She said it will still take a few weeks before they will be able to deploy them widely to the health care providers who have requested the tests. RELATED: Will you qualify for a ,200 COVID-19 stimulus check?One of the issues has been purely logistical.“In a typical manufacturing line there are a lot of people really close together. Even that's been a challenge to plan that,” said Dullanty. “We’re staggering shifts, taking time in between, cleaning the area well.” Right now, most tests are performed on-site then sent to a lab for processing. It can take several days or longer before a patient knows the results. RELATED: Dyson designs ventilator in 10 days, plans to make 15,000 of them to combat pandemicThe Mesa Biotech rapid test is based on the same PCR technology, but can be performed and processed at the point of contact, such as a hospital, urgent care clinic or a cruise ship infirmary. “We’re estimating having 5,000 - 10,000 a week,” said Dullanty on their production estimates. “Our discussion now that we are authorized is how do we scale that up?” The first batch should be shipped to providers in the next few weeks but it’s up to the health care systems to decide how and when to use them. RELATED: Company working to get FDA approval for fast COVID-19 test“There are some critical patients that maybe need the answer sooner. They are going to screen them in the ER. If it's a negative, they can release them and free up the hospital bed a day sooner,” Dullanty explained. 1871
SAN DIEGO (KGTV) — In the race for a coronavirus vaccine, scientists often say we need more than one winner.That’s in part because different vaccines use different strategies to provoke the immune system, and each strategy has different strengths.Take the inactivated virus vaccine, an approach currently used in the vaccine against the poliovirus. In this approach, scientists take a live virus, kill it with chemicals or heat, and then introduce that viral corpse into a person.There are three groups in the final phase of human trials using inactivated coronavirus, primarily in China, according to a tracker from the Milken Institute.“The immune system can tell the difference between something that's a real threat and something that's not a threat, and so if you get injected with a dead virus your immune system has the tendency to not pay a lot of attention to that,” said Dr. Shane Crotty of the La Jolla Institute for Immunology.The downside of the inactivated virus approach is that it only elicits two out of the three of the parts of the immune system, Dr. Crotty said. It’s capable of producing antibodies and helper T-cells, but not killer T-cells.The modern take on the inactivated virus approach is called a viral vector vaccine.In this strategy, scientists combine elements of the coronavirus with a common cold virus called an adenovirus that won’t make you sick. Since the virus is alive, it can elicit all three kinds of immune responses, Dr. Crotty said.“There are no licensed vaccines right now that use that strategy, but there are all kinds of vaccine trials that have been done around the world with those types [of vaccines] showing that they're straightforward to manufacture. They're very safe,” he said.The University of Oxford is testing a viral vector vaccine for COVID-19 in a Phase 3 clinical trial.Then there are subunit vaccines. These include just a section -- or subunit -- of the virus’ protein.UC San Diego is working on a coronavirus candidate vaccine using this approach.There are subunit vaccines currently on the market for tetanus and other viruses.“Working with proteins is more challenging, just from a laboratory and manufacturing perspective,” Dr. Crotty said.Enter the next phase of vaccine development. Instead of using the virus itself or fragments of it, Inovio Pharmaceuticals is working on a vaccine strategy using just the virus’ genetic information.DNA-based vaccines simply introduce a genetically engineered blueprint of the virus into a person, and the cells do the rest.“Some people get confused about this. They think it’s a genetic vaccine that changes their DNA and becomes part of them, and that’s definitely not the case.” Dr. Crotty said. “They don’t become part of you. Your body chews them up.”Researchers have been working on DNA-based vaccines for about 20 years, Crotty said, but none are currently licensed for use.San Diego-based Arcturus Therapeutics is using an RNA-based approach, along with other companies like Pfizer and Moderna that have entered Phase 3 trials.Messenger RNA reads the DNA instructions and helps translate them into proteins.Dr. Crotty said the DNA and RNA approaches have similar drawbacks and benefits: they’ve never been approved for us, but both can be developed rapidly because they don’t require access to the physical virus.Around the world, there are more than 200 coronavirus vaccines currently in development, according to the Milken Institute. 3459
SAN DIEGO (KGTV) - If violence is a learned behavior, so too then is non-violence. That’s the philosophy of two San Diego men who have worked together for 24 years to stop violence and save the lives of children. Azim Khamisa and Ples Felix have a message of peace-making to save the lives of children. The pair teach students in 5th through 9th grades the principles of accountability, empathy, peace building, and, above all, forgiveness. “We're not going to wake up and be in peace, We must teach restorative practices and create healthy kids, and healthy minds. Children who practice the principles of non-violence and actively commit themselves to becoming peace makers,” said Azim Khamisa. Khamisa started his journey after tragically losing his only son, Tariq Khamisa, when Tariq was 20 years old. As a college student working part-time, Tariq was lured to a gang house to deliver a pizza and fatally shot by then 14-year-old Tony Hicks. “It was like a nuclear bomb went off in my heart and I was broken into millions of small pieces. Violence is very real. It cuts deep and scars the soul,” Khamisa said. Khamisa founded the Tariq Khamisa Foundation to teach non-violence and took the extraordinary step of reaching out to Tony Hicks’ grandfather, Ples Felix. “I’m not here in a spirit of revenge...I'm here in the spirit of forgiveness because we both lost a son,” said Khamisa. Felix said he was praying for a way to reach out to the Khamisa family and provide support. He saw this as an answered prayer and accepted Khamisa’s hand of forgiveness. “To go forward in a way that in my life is totally unassociated with respect to that kind of trauma. I wanted to be with Azim's family...and commit to be of service any way I could,” said Felix. That was 24 years ago. The two men say they are now closer than brothers. Their safe school model is a 10-week curriculum, teaching lessons on empathy and compassion along with conflict resolution. The program also brings a peace club and leadership program to the schools. The results are staggering. The program has been shown to cut truancy and expulsion rates by 68 percent and increase conflict resolution peacefully by more than 90 percent. Khamisa and Felix have reached almost 600,000 students and, through digital and television coverage, the figure is easily into the millions. Former students such as Rocio Hernandez credit the program with saving her from despair, violent revenge, and thoughts that life isn’t precious. “On the way home from school I was attacked by gang members...I was only in the 7th grade. That could have been a turning point in my life. I could have turned violent myself. It’s crazy how the Tariq Khamisa Foundation came into my life at the right time. I remember coming out of that assembly empowered like I could take on the world,” said Hernandez. Hernandez now lives a positive, productive life and speaks to young people about her journey to happiness. It’s a journey that started with forgiveness, which Khamisa calls a gift you give yourself. “Mandela has a great quote: Resentment is like taking poison, and waiting for your enemy to die.” 3146
SAN DIEGO (KGTV) -- Law enforcement agencies in San Diego County have a new tool in the fight against child predators: Southern California’s first electronics-sniffing dog. Willow, a 2-year-old yellow Labrador, is trained to sniff out the chemical used to coat all kinds of electronic storage media, including microSD cards, thumb drives, hard drives, cell phones and tablets.She works in partnership with the Internet Crimes Against Children Task Force (ICAC), the San Diego Police Department and the San Diego County District Attorney’s Office.“Our whole goal with ICAC is to save kids,” said Willow’s handler Ron Burleson. “If they’ve got any homemade images, there’s a kid out there that needs to be rescued, needs to be found. So that can make all the difference in the world when we can find that hidden media.”RELATED: Dog eats marijuana, develops 'scary' symptomsK9s have a long history in law enforcement as drug, arson and bomb-sniffing dogs, but this sniffing specialty has only been around since 2012, when Connecticut State Police trained the world’s first electronic storage detection K9. The breakthrough came after Connecticut State Police chemist Dr. Jack Hubball discovered that all media with a circuit board -- like hard drives, thumb drives and SD cards -- is covered with a chemical to prevent overheating called triphenylphosphine oxide (TPPO). Once trained, dogs will sniff out the chemical for a reward. In Willow’s case, she gets three cups of food a day, and only after she sniffs out a device.“Two or three times a day, I’m hiding storage media and then we’re training, we’re working,” said Burleson. “That’s how she gets fed.”RELATED: 10news viewer helps burglary victim reunite with stolen puppyWillow spent four months training with Todd Jordan, whose first electronics detection dog, Bear, made a key discovery in the child sex crimes case against former Subway spokesman Jared Fogle.Willow has been on the job in San Diego County since November and took part in her first local search a few weeks ago at the home of a registered sex offender.“And we searched the house and she was able to find a cell phone that had been missed previously during the search,” Burleson said.Although Willow has a narrow specialty, Burleson said she’ll be busy. San Diego ICAC will have about 2,000 cases this year, he said.When she’s not working, Willow lives with Burleson. “I’ve had many requests that the next time any friends or family lose their cell phone, they want me to bring Willow over,” he said.The funding to buy Willow, who cost about ,000, came from the San Diego Police Foundation through an anonymous donor, Burleson said. 2667
SAN DIEGO (KGTV) — Local Regal Cinemas are offering an affordable day at the movies all summer long.Regal Cinemas' "2019 Summer Movie Express" series offers movie tickets to select kid-friendly films at 10 a.m. on Tuesdays and Wednesdays at participating theaters.In San Diego, participating theaters include Regal Edwards San Marcos, Regal Escondido, Regal Mira Mesa, Regal Edwards Rancho San Diego in El Cajon, and Regal Partway Plaza in El Cajon.RELATED: Summer Movies in the Park return to San DiegoMoving seats, weather effects come to Mira Mesa theaterAnd movie-goers will be able to enjoy a variety of kid-favorite films like "The LEGO Movie 2," "Secret Life of Pets," "Kung Fu Panda 3," "How to Train Your Dragon," and several more.For a full list of movies and participating locations, visit Regal's website here. 833