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At Uptown Wines, Beer & Spirits, sales have surged since the COVID-19 crisis started and are expected to rise even more during the holidays.“Last time I’ve seen sales like this, it would be considered New Year’s, Thanksgiving and Halloween night,” said beer specialist Wiley Deerman.Deerman says with more people quarantined at home many started stocking up on alcohol to-go.“We’ve seen a lot of these half-sized bottles, the sales have increased on those,” he said.Now, new research from Vanderbilt University shows not only are more people drinking alcohol and abusing other drugs during the pandemic, but that this increase could create new addicts as well.“You’re seeing an increase in drinking, in drug use in people at home. When the pandemic’s over, this isn’t going to go away," said Erin Calipari, Ph.D., with the Vanderbilt Center for Addiction Research.Calipari’s team conducted the study, which shows addiction triggers during the COVID-19 crisis could make the holiday season even worse for many adults struggling with sobriety.To help fight this problem, Calipari says America needs the same kind of investment in battling addiction as is being put into solving the pandemic.“Addiction kills just as many people as the pandemic has this year and we haven’t done the same thing,” she said. “We’ve kind of, you know, funded it a little bit but we haven’t had this community investment and this kind of global revelation that this is a problem that we should be solving.”Without proper attention, Calipari predicts addiction cases will continue to increase across the country, even after there’s a cure for COVID-19.“This isn’t going to go away when we get the vaccine or solve the pandemic,” she said. “This is going to be a kind of long-term problem that we’re going to have to deal with as a society.”A very costly problem both in money and human lives.That’s why Deerman’s business focuses on more than making a buck, saying the best way to serve his community is to sometimes actually not serve them at all.“There’s times where we have to say, ‘Look, I think you need to cut back, take it easy. we care about you,’” he said.Care about stopping an addiction before it even starts. 2203

ATLANTA, Ga. – The Centers for Disease Control and Prevention (CDC) is warning parents to be on the lookout for symptoms of acute flaccid myelitis (AFM) in children.The public health agency said Tuesday that it anticipates that 2020 will be another peak year AFM, an uncommon but serious neurologic condition that affects mostly children.AFM can progress rapidly over the course of hours or days, leading to permanent paralysis and/or the life-threatening complication of respiratory failure in previously healthy patients, so it’s important to seek medical care as soon as possible.The disease has peaked every two years between August and November in the U.S. since 2014, when the nation experienced the first peak of 120 cases, according to the CDC. There were also peaks in 2016 and 2018.The third and largest peak of AFM occurred in 2018, with 238 cases in 42 states. Most cases were in children (94%) and most patients (86%) had AFM onset during August through November. Most patients had a fever and/or respiratory illness approximately six days before limb weakness onset. Other common early symptoms were difficulty walking, neck or back pain, fever, and limb pain.The CDC says parents and doctors should suspect AFM in patients with sudden limb weakness, especially during August through November. Recent respiratory illness or fever and the presence of neck or back pain or any neurologic symptom should heighten their concern.Experts say enteroviruses, particularly enterovirus-D68 (EV-D68), are likely responsible for these peaks in cases. EV-D68 is the most common virus identified among specimens collected from patients with AFM. However, other viruses can cause AFM and may also be contributing to the biennial peaks.Although AFM symptoms resemble those of polio, all specimens have tested negative for poliovirus.There is currently no specific test, proven treatment or prevention method for AFM.“As we head into these critical next months, CDC is taking necessary steps to help clinicians better recognize signs and symptoms of AFM in children,” said CDC Director Robert Redfield, M.D. “Recognition and early diagnosis are critical. CDC and public health partners have strengthened early disease detection systems, a vital step toward rapid treatment and rehabilitation for children with AFM.”AFM and COVID-19The CDC says AFM is a medical emergency and patients should seek immediate medical care, even in areas with high COVID-19 activity.It’s not known how the COVID-19 pandemic and the social distancing measures may affect the circulation of viruses that can cause AFM, or if COVID-19 will impact the health care system’s ability to promptly recognize and respond to AFM.There is one bright side. If social distancing measures decrease circulation of enteroviruses this year, AFM cases may be fewer than expected or the outbreak may be delayed.Learn more about AFM here. 2901

At least five people have been killed in a ferocious storm that hammered the Northeast with powerful winds, relentless rain and historic flooding.The nor'easter moved out to sea Saturday, but not before it knocked out power -- perhaps for days -- to more than 900,000 customers from the mid-Atlantic to New England."People in these homes need to plan for a prolonged outage," Kurt Schwartz, director of the Massachusetts Emergency Management Agency, said Friday night. "This is a multi-day restoration event."RELATED:?'Bomb cyclone' pounds east coast with heavy flooding, high winds   The flooding is "the worst that we've seen in years," said Capt. John Dougan of the Quincy, Massachusetts Police Department, which had carried out more than 250 rescues between 8 a.m. Friday and midmorning Saturday. "We're seeing homes underwater, their basements were flooded out, the electricity was off."Emergency officials urged residents on higher ground to stay indoors, even after the storm pushed out."This is not a time to be out sightseeing and gawking, so please stay at home and stay out of our way," James Boudreau, the town administrator for Scituate, Massachusetts, said Saturday.Some 19 million people were still under a coastal flooding warning early Saturday afternoon.The storm morphed Friday into a "bomb cyclone" after undergoing a rapid pressure drop known as bombogenesis. It slammed much of the Northeast with heavy snow and rain, prompting significant coastal flooding and hurricane-force gusts in New England.Winds along parts of the Massachusetts coast that whipped in excess of 90 miles per hour are due to ease Saturday, CNN forecasters said.The storm also dumped heavy snow from Ohio to New England and into upstate New York, where more than 3 feet was recorded.Weak phone connection? Click here to read text-only versions of CNN's top stories.Latest developments? Power outages: More than 900,000 customers were without power Saturday from Virginia to Massachusetts.? Aftermath response: The governors of Maryland and Virginia issued emergency declarations, allowing state and local agencies to help those affected.? Flight cancellations: About 250 flights in the storm zone were canceled Saturday, according to the flight-tracking website FlightAware.com. That compares with more than 3,000 US flights scratched Friday, most at the busiest Northeast airports in Boston, Philadelphia and New York.? Amtrak back in service: Amtrak resumed modified service at 6:20 a.m. ET Saturday, on its Northeast Corridor between Washington and New York, and planned to resume service between New York and Boston beginning at 8:40 a.m., the provider said.Five killed by falling treesAt least five people died in the storm, all killed by falling trees, authorities said. They include: a 77-year-old woman in Kingsville, Maryland; an 11-year-old boy in Putnam County, New York; a 44-year-old man in James City County, Virginia; a 6-year-old in Chesterfield County, Virginia; and a Newport, Rhode Island, man in his 70s.The 11-year-old was in his home when a large tree came crashing down, trapping him. A responding deputy tried to free the boy, whose mother was taken to hospital.Another young boy, just 6 years old, suffered a similar fate when a tree fell through his Virginia mobile home as he was sleeping on a top bunk bed. The boy was rushed to hospital, but his mother told the station his organs were failing."Doctors say we have to let him go," she told CNN affiliate WRIC. Cynthia Creighton's son was in her car when a neighbor's tree fell on top of the vehicle in Watertown, Massachusetts."The house shook, and we heard a noise. We didn't know what it was," Creighton told CNN affiliate WHDH. "We ran out, my son was still in the car with the tree on top of it."Creighton's son, who was in the back seat, was not injured, she said.Boston under waterHigh tides on Friday powered coastal flooding in Boston and other parts of Massachusetts, leaving streets awash for the second time since a massive nor'easter in early January.Kayakers paddled down Boston streets and National Guard members rescued 50 people from their homes in nearby Quincy, sometimes carrying them to safety in the scoopers of front-end loaders, CNN affiliate WBZ reported.Boston Harbor has only seen tides above 15 feet twice -- in 1978 and in January, during the last bomb cyclone. A high tide late Friday morning came up a little short, reaching 14.67 feet, but still sent water sloshing through the streets of East Boston.More record-setting high tides might strike Boston Harbor on Saturday during the midday high tide.With the moon full, the tide is at its highest point of the month, and the storm surge could drive as much as 4 feet of water into coastal neighborhoods, CNN meteorologists said. Massachusetts emergency officials said tides "will be astronomically high" in the next few days."I encourage all residents to be mindful of the storm and encourage employers to take the weather into consideration, which will mostly impact the coastal areas of our city," Boston Mayor Marty Walsh said.In Boston, many streets were closed and city officials advised people not to drive or walk in high water.Historic flooding prompts rescuesQuincy residents who were rescued from inundated homes told CNN they'd never seen anything like this weekend's flooding."It was pretty scary," said Alyssa Fitzgerald. "Once you saw the National Guard, that's when I was like, 'OK, we should have evacuated.'"Fitzgerald and her husband hunkered down overnight after their home lost power with their 3-year-old son and 1-year-old daughter, she said."Not like anything we've had before," Fitzgerald said. "Much worse than the snowstorm we had."Only a few storms even can compare with this level of flooding, including a 1978 blizzard, a storm in 1991 and January's bomb cyclone, Dougan, the Quincy police captain, said Saturday."We've been doing evacuations all through the night and today," he said.The-CNN-Wire? & ? 2018 Cable News Network, Inc., a Time Warner Company. All rights reserved.  6092

Authorities and the Sacramento Kings are preparing for protests that are expected Thursday after the funeral for Stephon Clark, an unarmed black man who was killed by police in his grandmother's backyard.Over the past week, the Kings have found themselves at the center of the conflict between police and outraged members of the community.Protesters have blocked the entrance to the arena on two occasions in protest over the March 18 shooting. Last Thursday, the protest forced the Kings and Atlanta Hawks to play in a nearby empty arena.On Tuesday, the doors of the arena closed as protesters arrived, again preventing fans from getting in.Sacramento police said Wednesday they are talking with team officials to plan for the Thursday game against the Indiana Pacers. Tip off is at 7 p.m. PT (10 p.m ET).Clark's funeral is scheduled to take place from 11 a.m. to 1 p.m. PT, a little more than seven miles from the NBA arena."We don't know exactly what we'll be doing. We will assess every situation as it presents itself," Sacramento Police spokesperson Sgt. Vance Chandler told CNN.In a tweet, the Kings said they are also meeting with Sacramento Mayor Darrell Steinberg and community leaders. Team officials said they "are committed to ensuring the safety and security of fans on Thursday and future events."The fatal shooting took place after Sacramento officers responded to a report that a man had broken car windows and was hiding behind a home. Police said they pursued a man -- later identified as Clark -- who hopped a fence into his grandmother's property.The officers said they shot Clark, 22, because they believed he was pointing a gun at them, police have said. Investigators only found a cell phone near his body.The officers -- one of whom is black -- have been placed on administrative leave amid a use-of-force investigation.Clark's family has disputed the police's account. 1927

As we're all focused on the current rollout of the COVID-19 vaccine, a technology known as thin-film freezing is getting a lot of attention. It's groundbreaking and could change the way we administer drugs or use medicine in general.You've probably heard about the need to keep the COVID-19 vaccine cold. It has to be so cold, in fact, that the shipment and transport are challenging. Well, what if that vaccine could be turned into powder?“What we’ve most recently been working on is the elimination of cold chain by storing as a powder, a dry powder where the drug is much more stable than if it was stored as a liquid or as a frozen liquid,” said co-inventor Dr. Robert Williams.Williams said it would eliminate the need for extreme cold storage and transport. The technology isn't new. He got a research grant and came up with it about 15 years ago.Williams, who is also a pharmacy professor at the University of Texas in Austin, said they were working on the technology and its multiple uses when the pandemic hit. And all of a sudden, they got a lot of attention.“We have published over 70 papers on the technology and using it for different products- it’s quite a mature process," Williams said. "We developed it because with other vaccines, the majority of the vaccine cost is in wastage because of this cold chain issue, so we published several key papers where we showed our thin-film freezing technology would protect vaccines - and you wouldn’t need cold chain storage.”Glenn Mattes, President, and CEO of TFF Pharmaceuticals added that the powders can be converted to topical preparations and they are currently working with the US Army to take some of the preparations and would then administer them directly through the eye.TFF is launching thin-film freezing into development through the FDA process. “I use the term ubiquitous because it is and disruptive because it is,” Mattes said. He added that they've explored their technology in the cannabinoid realm. But, as for the COVID vaccine, they're aiming for a second-generation usage.“To truly eradicate the pandemic, you have to have a global response," Mattes said. "The companies we’ve been speaking to certainly recognize the broad utilization of the technology but the application to the developing world, rural area, remote areas, where you can take a powder and inhale it or take the powder and reconstitute it has tremendous potential."Experts say it is only just the beginning as they launch their technology into a new world. 2511