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The US Food and Drug Administration approved two cancer treatments, Vitrakvi and Xospata, this week after expedited reviews.Vitrakvi, approved Monday, is "a treatment for adult and pediatric patients whose cancers have a specific genetic feature (biomarker)."The FDA said in a statement that it is the second approved cancer treatment that is based on a tumor biomarker instead of the place in the body where the tumor originated.Vitrakvi will be used for the treatment of solid tumors that have an NTRK (neurotrophic receptor tyrosine kinase) gene fusion that do not have a known resistance mutation, that are not metastatic or where surgical removal is likely to lead to severe morbidity, and that have no alternative treatments or have progressed after treatments.NTRK genes are rare but occur in many types of cancer, the FDA said, such as mammary analogue secretory carcinoma and infantile fibrosarcoma.Xospata tablets, approved Wednesday, are for the "treatment of adult patients who have relapsed or refractory acute myeloid leukemia (AML) with a FLT3 mutation," according to the FDA.Alongside the tablets, the agency also approved a diagnostic to detect the mutation."Approximately 25 to 30 percent of patients with AML have a mutation in the FLT3 gene. These mutations are associated with a particularly aggressive form of the disease and a higher risk of relapse," Dr. Richard Pazdur, director of the FDA's Oncology Center of Excellence, said in the statement.AML is a rapidly progressing cancer that affects the numbers of normal blood cells and calls for continuous transfusions, the FDA said.Both treatments were granted Priority Review designation.Priority Review, established in 1992, means the FDA aims to review the drug or treatment within six months, opposed to 10 months for a standard review."A Priority Review designation will direct overall attention and resources to the evaluation of applications for drugs that, if approved, would be significant improvements in the safety or effectiveness of the treatment, diagnosis, or prevention of serious conditions when compared to standard applications," the FDA says.Both treatments also received?orphan drug?designation, a status granted to drugs for rare diseases or conditions. 2261

The US House of Representatives will vote on whether to legalize marijuana across the country in September. This would be the first time a chamber of Congress has ever voted on removing marijuana from the Controlled Substances Act.Cannabis was included as what is called a Schedule I drug under the Controlled Substances Act in 1970. Schedule I drugs are defined as having a high potential for abuse and no medical benefit. Other Schedule I drugs include heroin, LSD, ecstasy and peyote.On Friday, representatives were informed the MORE Act will come up for a vote in the September work period of the House.The MORE Act - Marijuana Opportunity Reinvestment and Expungement Act - will expunge some cannabis records and create grant opportunities for people who have been negatively impacted by the criminalization of marijuana in addition to removing it from its Schedule I classification, according to Politico.Marijuana is already legal in 11 states, despite the federal designation as a Schedule I drug.Senate Majority Leader Mitch McConnell is opposed to the act, and some say the odds of it passing the senate are very slim.Even if the MORE Act passes both chambers of Congress, it would not make sales of marijuana legal. Regulation of marijuana would be left to states to decide how to handle it. 1310

The terms "signing bonus: and "recruiting" are usually reserved fro top-paid professional athletes. Now add nurses to that list.Hospitals across the country are facing a shortage of nurses, and they're stepping up the incentives to fill the jobs.Patients aren't the only ones happy that Christina Predo is working at UCHealth. After all, the hospital gave her a ,000 signing bonus as an incentive to take the job."Other offers before that hadn't even come close," Predo said.Predo needed to find a job where her husband was being relocated. With several offers on the table, in the end it was UCHealth's signing bonus and other perks that sealed the deal."They offered all sorts of help to help move here," Predo said. "They offered someone to actually find me a neighborhood to live in which was awesome. None of the other hospitals actually offered to do that."What's behind the big bonuses? A shortage of nurses. With more than 500,000 seasoned registered nurses expected to retire by 2022, there's a projected need for 1.1 million new nurses to avoid a shortage.Hospitals across the country, including UCHealth, are feeling that crunch already."Well I'll tell you what, we have about 300 positions open," said Kathy Howell, Chief Nursing Executive at UCHealth.Howell says growth has created a greater demand for nurses, and a good economy means more nurses are opting to retire. That's why there's a concerted effort to make the offer to work at UCHealth as attractive as possible, even allowing out-of-state nurses to try out the hospital for a year and covering their housing costs."They go from assignment to assignment within our health system," Howell says. "We also give them a housing stipend, and we usually convert between 35 and 40 percent of them to full-time employees."Most new nurse hires get around ,000 to sign, which Howell doesn't think is out of line."When you look at what turnover of nurses costs and what not having the right nursing complement is to your hospital," Howell says. "That is a very reasonable investment."Ultimately, Howell says it's about delivering the right care to patients, and creating the right environment for the nurses they hire."It's a real comradery. Everyone is super super nice, you really have a say in what you're doing here, your opinion actually matters you don't feel like a number," Predo said.A new way to fill the need for nurses, with a payoff, multifold. 2476

The travel industry has taken a major hit during the COVID-19 pandemic. From hotels to airlines, the industry saw a massive dip in business as people started canceling their upcoming trips. Instead, it appears people are taking their summer vacations outdoors."We had a lot of cancelations early on so starting in March, April and May we're heavily affected by cancelations but now that states are opening back up and travel’s resuming, our bookings are outpacing our cancelation seven fold," says Toby O'Rourke, the CEO of Kampgrounds of America. O'Rourke says campsite bookings and RV rentals are soaring.KOA conducted their own research and found that one-third of non-campers are considering camping as their summer travel activity. With contact-less bookings and a taste of the outdoors, she says many are finding camping a safer vacation option."We've been having a lot of activity on our campgrounds. There’s a lot of pent-up demand. We’re seeing June really take off which we’re excited to see heading into the summer months," says O'Rourke.O'Rourke adds that a majority of states have opened up their parks and campgrounds. In April, she says there was a magic date when people started booking campgrounds like crazy. Outdoorsy.com, a site that connects RV owners with people who want to rent them, says they've seen a 2,600% growth in their business since the COVID-19 pandemic began."Just last month alone, we saw over 2.5 million new visits or new users to the site Outdoorsy.com which is pretty significant. We’re breaking records all over the place in terms of bookings, growth. We had our best booking day on record last week that was up 300% year over year for just that day," says Jennifer Young, co-founder of Outdoorsy.com.Outdoorsy says recreational vehicles allow people to control their own environments."It's a standalone vehicle that you control where you buy your food, where it goes, how it stays in your refrigerator. Same with your bathrooms. So you’re cleaning and washing and showering - it's all self-contained in where you want to stay. You pick your location and destination," says Young.Plus both Outdoorsy and KOA have developed new safety guidance for campgrounds and RV renters amid COVID-19 which include proper sanitation, personal protective equipment and more."I definitely think once somebody rents an outdoorsy vehicle or camper van I’m pretty sure they’ll be hooked," says Young.KOA's O'Rourke advises people to first check camping websites and book ahead whenever possible. Helping people social distance while still leaving their house for a vacation. 2605

The United Nations Security Council unanimously adopted a US-drafted resolution to impose new sanctions on North Korea on Monday --- a move that comes just one week after the rogue nation carried out its sixth and largest nuclear test.The resolution is designed to accomplish six major goals: cap North Korea's oil imports, ban textile exports, end additional overseas laborer contracts, suppress smuggling efforts, stop joint ventures with other nations and sanction designated North Korean government entities, according to a US official familiar with negotiations.On Monday, the US?circulated a draft resolution that called for a full ban on exports of oil to North Korea and an asset freeze?on leader Kim Jong Un, the Worker's Party and the government of North Korea.But later in the day, the US put forward another draft that removed the full oil embargo, asset freeze, travel ban for Kim and softened the language on foreign workers and other issues. 974

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