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LA JOLLA (KGTV): Researchers at the UC San Diego Moores Cancer Center and the La Jolla Institute of Allergy and Immunology have teamed up to find a new way to fight cancer.They've created a vaccine that can help teach the immune system how to attack only cancer cells and leave the rest of the body alone."Patients will be able to tolerate their therapy much better than they have so far on conventional approaches," says Dr. Stephen Schoenberger from the La Jolla Institute.Each vaccine is highly personalized to the patient. According to a release from UC San Diego, the vaccines "defines the neoantigens – foreign protein fragments recognized by the immune system – in a patient’s cancer. With neoantigens identified, the team can identify peptides – strings of amino acids – that can be used to create a vaccine to stimulate a protective immune system response."Simply put, the new vaccine takes information from a patient's immune system and the tumor and uses it to help white blood cells to fight it."We're giving them life and giving them hope," says Dr. Schoenberger.The first patient in the clinical trial is Tamara Strauss. She was diagnosed with pancreatic cancer in 2015 and went through chemotherapy and surgery."It was brutal," says Strauss. "It's been three and a half years of hell."Strauss' parents helped fund the clinical trial with a million donation. She says she feels fortunate they could do that, but also hopeful that it helps others down the road."I really pray that this vaccine and personalized form of treatment really does change the paradigm of cancer treatment," says Strauss.During the trial, ten patients will get three doses of the vaccine. They'll also be on Keytruda, an immune system boosting drug for up to two years. Their health will be monitored for five years to determine the vaccine's effectiveness. 1871
Kimberly Kinell is used to having a routine. She’s up at 7:30 every morning, makes her coffee, and starts folding up her bed inside the New Haven, Connecticut hotel she’s now living in.It’s a routine she learned out of necessity while sleeping in a homeless shelter each night and spending her days on the streets.“We had to go outside and leave the building at 7:30 in the morning and not come back until 4,” said Kinell. “I had a tent on my back and two dogs.”Addiction kept her from a stable life. Kinell said the loss of her father and her husband hurled her into a battle for sobriety.“I was drinking,” she said. “Those days were dark, and it ended up putting me in a full-blown depression.”Her depression was so deep at times, she saw no future of happiness. “When you’re drinking or under the influence, everything seems dark and everything seems, my life just seemed unlivable,” she described.But there was a wake-up call, from an unexpected place. “The dogs made me do the right thing,” said Kinell. “They gave me a point to live, it was like getting up every day because I have to take care of them.”After watching the dogs struggle to survive without consistent food, she checked into a rehabilitation program.“I was there for 51 days, and when I got out, there was no place to go,” said Kinell.Terrified of going back to the life she knew, she got help from the Columbus House emergency shelter.“They just treated me like I wasn’t garbage, like I wasn’t throw away, brought me into a nice warm bed,” she said.But once COVID-19 hit, the shelter became just as threatening as the streets.“One room would hold like 10 people,” she said. “It was very, very touchy in the beginning because you’re just very scared.”Melinda Mallory, the director of emergency services for Columbus House, said the organization that provides shelter for countless homeless members of the community each night did everything they could to social distance and make hygiene top priority within the shelter.“We quickly realized despite all the changes we were making inside, we still needed to address the congregate living issue,” said Mallory.The solution: move everyone relying on the shelter into local hotels. With coordination from the city, Columbus House has been able to get more than 200 homeless people off the streets, out of shelters, and into hotel rooms during the pandemic.“They’re able to build upon their independent living skills while they’re here," said Mallory. "We’re teaching them community so they’re learning to be good tenants, to be good roommates."Now, a few months into the program, its success is becoming clear. It started as an effort to stop COVID-19, but it is now starting to look like a natural transition from homelessness to independence.“I hope that this hotel experience can go on a little longer, because it’s the first step of a person really understanding what it takes to really be out on their own,” said John Sanford, manager of emergency services at Columbus House.But, not everyone is on board for keeping this new model.“A lot of people do have the 'not in my neighborhood,' and a lot of landlords that don’t want to rent to our population, so affordable housing is always a challenge for the individuals we serve. But I always say, “if not there, then where?'” said Mallory.The struggle for affordable housing is too tough to overcome for more than half a million Americans who are homeless.“We have people who are CNAs, we have people that used to be professors, you just never know when life will happen and when you’ll need a little more assistance,” said Mallory.For Kinell, having a room she doesn’t need to leave every morning is helping her focus on what’s next instead of surviving the day.“That’s what it means to me,” said Kinell. “It means privacy, and it gives me hope in life that I am gonna get this job. I am gonna get this apartment, and I am optimistic as all can be.”A permanent home and a permanent job are the end goals Mallory and her team are trying to help all their clients reach in a time when both are tougher to find than ever before.“Once an individual has housing, all the other things will fall into place,” said Mallory.Kinell is seeing things begin to fall into place. It's a process that all started the day she checked in for a second chance.“I’m going on a year sober, I’m happy, no more tears,” she said. “I’m looking forward to moving ahead. I think it’s my time.”For more information on Columbus House, click HERE. 4495
Jurors have found Border Patrol Agent Lonnie Swartz not guilty on the Second Degree Murder charge of shooting through the border fence and killing 16-year-old Jose Antonio Elena Rodriguez.Jurors could not come to an agreement on a verdict on the two lesser charges, voluntary manslaughter and involuntary manslaughter.If they wish, prosecutors can retry Swartz on the lesser charges only.Friday jurors told Federal Judge Raner Collins they could not agree on a verdict. The judge told them to continue deliberating. They could choose to convict Swartz on lesser charges of Voluntary Manslaughter or Involuntary Manslaughter.Swartz testified he was protecting himself and other officers from rocks thrown over the border fence by people on the Mexican side trying to interfere with efforts to arrests smugglers who were trying to climb over the fence and into Mexico.In closing statements to the jury, prosecutors said in his two years as a Border Patrol Agent, Swartz had rocks thrown at him six or seven times, and each time had responded by using less lethal weapons. Border Patrol may use items like guns that shoot an irritating pepper.But the night of October 10, 2012, Swartz had been on duty at the DeConcini Port of Entry. He had only his gun and used it to fire 16 rounds through the fence. Ten shots hit the 16-year-old Mexican teen.Prosecutors say the threat against Swartz and other officers was not severe enough to justify deadly force and that they could have easily removed any threat by taking cover.They say other agents took cover but Swartz was fed up with rockings, wanted to send a message, and did it by calmly walking to the border fence, taking careful aim, and firing 16 shots into Mexico.Defense attorney Sean Chapman told the jury rocks are enough of a danger to justify deadly force and that there is no evidence to conclude Swartz fired out of anger over rock attacks. He said jurors should not base their verdict on surveillance video of that night because it is low quality and attempts to enhance it may have altered what it shows.RELATEDTrial beginning for US agent in?cross-border?killing of teenUS agent goes on trial in Mexican teen cross-border killingFederal?judge says border agent's military record off?tableCross-border killing: Should BP Agent's Army AWOL be evidence?Border agent asks?judge?for night border visit by juryJudges?refuses?to oust prosecutors from border shooting caseBP Agent in?cross-border?murder case was forced out of ArmyCross Border?Killing: Prosecutors won't dispute teen was throwing rocksSurveillance disputed in cross-border shooting caseBorder Patrol agent's trial in Mexican killing delayedVigil for Mexican teen killed in border shooting: BP agent charged with his deathBP Agent's murder trial to stay in Federal CourtMurder case against Border Patrol agent to move forwardCross-border killing video challenged 2922
Kentucky Attorney General Daniel Cameron met with the family of Breonna Taylor Wednesday.Cameron's spokeswoman Elizabeth Kuhn said the meeting was an opportunity for the attorney general to personally express his condolences to Taylor's family.Kuhn released the following statement after the meeting: Attorney General Cameron was grateful today to meet with the family of Ms. Breonna Taylor, including Ms. Tamika Palmer, Ms. Juniyah Palmer, Ms. Bianca Austin, and the family's attorneys, as well as Christopher 2X from the Game Changers organization. The meeting provided an opportunity for Attorney General Cameron to personally express his condolences to the family. The investigation remains ongoing, and our Office of Special Prosecutions continues to review all the facts in the case to determine the truth. Taylor, 26, was killed on March 13 by Louisville police executing a now-banned "no-knock" warrant.One of the officers, Brett Hankison, was fired. The other officers involved in the case — Jon Mattingly and Myles Cosgrove — have been placed on administrative reassignment. None of the officers face criminal charges.This story was originally reported by WLEX. 1189
Joe Biden's two surviving children Hunter and Ashley Biden introduced their father moments before he accepted the Democratic nomination for president on Thursday.Also joining Hunter and Ashley was Beau Biden, whose words from a past convention were added to the introduction. Beau Biden died in 2015 after a battle with brain cancer."We want to tell you what kind of president our dad will be. He will be tough and honest, caring and principled. He'll listen, be there when you need him. He'll tell you the truth even when you don't want to hear it. He'll never let you down,” Hunter and Ashley Biden said, trading lines.Hunter Biden became a household name last year when word came that President Donald Trump called on Ukrainian President Volodymyr Zelensky to investigate Hunter Biden’s role with Burisma, an oil firm owned by a Ukrainian. Hunter Biden held a job with the company as his father served his second term as vice president.As vice president, Joe Biden was among western leaders who called for the exodus of Ukrainian prosecutor Viktor Shokin. Trump and the White House tried to claim that Biden's push to ouster the prosecutor was influenced by his son's role with Burisma, but both Republicans and Democrats on Capitol Hill in addition to other western nations joined in calling for the ouster of Shokin.The controversy with Hunter Biden was a campaign issue early on during the primaries."My son did nothing wrong," Joe Biden said during an October debate. "I did nothing wrong. I carried out the policy of the United States government in rooting out corruption in Ukraine. And that's what we should be focusing on." 1642