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Horseshoe crabs are prehistoric creatures that predate the dinosaurs, but pharmaceutical companies depend on them to this day for their unique blue blood.The crabs’ blood is hypersensitive to endotoxins, making it the perfect testing ground to see if a coronavirus vaccine is harmful to people."The fact that we rely so much on these really primitive creatures that predate the dinosaurs," said Barbara Brummer, the state director of The Nature Conservancy in New Jersey.From Massachusetts to South Carolina, the crabs are collected and taken to laboratories. But one of their largest breeding grounds is right in New Jersey, in the Delaware Bay."The concern is the population of horseshoe crabs in the Delaware Bay has been declining over the years," said Brummer. "They are needed for the ecological value they bring for shorebirds.”Shorebirds rely on the crabs' millions of eggs for food.New Jersey fishermen are banned from using the crabs for bait. But pharmaceutical companies remove about a half-million horseshoe crabs from the ocean every year.In the labs, about one-third of a crab's blood is removed for testing. If the crab's blue blood clots up, the medicine is no good.The crabs are then returned to the ocean.However, a study by the Atlantic States Marine Fisheries Commission estimates about 15% of the crabs do not survive."There is an alternative test," Brummer said. "They have created a test that does not involve the bleeding of the crabs. It is a synthetic material."The synthetic test has been approved in Europe but has not yet been approved in the United States.This story was first reported by Christie Duffy at PIX11 in New York, New York. 1674

Here's a look at rampage killings that have occurred in the United States since the 1940s. Includes incidents with four or more killed (not including the perpetrators). Not included are suicides, gang-related incidents or deaths resulting from domestic conflicts.US Timeline (selected only): 299

Gun deaths in America have reached a record high.Nearly 40,000 people in the United States died by guns last year, marking the highest number of gun deaths in decades, according to a new analysis of data from the Centers for Disease Control and Prevention's WONDER database.A similar analysis was first conducted by the Educational Fund to Stop Gun Violence, a non-profit gun policy advocacy group.CNN replicated that analysis and found that 39,773 people died by guns in 2017, which is an increase of more than 10,000 deaths from the 28,874 in 1999. The age-adjusted rate of firearm deaths per 100,000 people rose from 10.3 per 100,000 in 1999 to 12 per 100,000 in 2017.CDC statisticians confirmed with CNN on Thursday that these numbers are correct and they show gun deaths have reached a record-high going back to at least 1979, which was the year firearm deaths started to be coded in mortality data.CNN's analysis also showed that 23,854 people died from suicide by guns in 2017, the highest number in 18 years. That's a difference of more than 7,000 deaths compared with 16,599 suicide deaths by guns in 1999.The age-adjusted rate of suicide deaths by firearm rose from 6.0 in 1999 to 6.9 in 2017.Firearm deaths in the data include gun deaths by homicide and suicide, unintentional deaths, deaths in war or legal interventions, and deaths that are undetermined.When the data are analyzed by race and gender, they show that white men made up 23,927 of the total 39,773 firearm deaths last year, including suicides.In 2017, the age-adjusted rate of suicide deaths by firearm was highest among white men at 14 per 100,000 -- compared with: 1650

Greg Eubanks disappeared over the weekend, leaving his family frantic. Two days later, he was at home, safe.The 41-year-old had crashed his SUV around 3 a.m. Saturday in Oxon Hill, Maryland. The SUV went down an embankment and got stuck between the highway entrance and exit ramps, so his car wasn't visible from the road.Eubanks was hurt when he was thrown from the SUV. He was left laying at the bottom of the ravine with broken bones and a dead cell phone for two days and three nights. "He said he didn't think he was gonna make it," Tre Drew, Eubanks' cousin, said. "He heard several fire trucks passing, ambulance passing. He kept saying 'I know they're coming for me' and no one came for him."Eubanks' son, Greg Eubanks Jr., reported him missing Saturday, then drove around searching for his dad. "I was worried. I couldn't sleep. (I) rode around all day yesterday trying to find his car, just looking for any type of piece of evidence," the younger Eubanks said.A highway crew finally spotted Eubanks and his car while repairing a damaged guardrail on the Indian Head Highway. "He said it was the worst thing he's ever been through, and he has been through a lot," Drew said.Eubanks was taken to the hospital for treatment. His family says he is in good spirits and is expected to make a full recovery. Maryland State Police are investigating. 1419

HAMPTON ROADS, Va. - As coronavirus continues to rage across the country, scientists are inching closer to developing a COVID-19 vaccine.Dr. Doug Mitchell used to be a pediatric infectious diseases specialist at CHKD and EVMS. He is currently the medical director of CHKD Medical Group and a pediatrician at Norfolk Pediatrics.“If we’re able to stick to the science in developing the vaccine, then that would be comforting if we could stick to the science and develop an effective and safe vaccine,” said Mitchell.Mitchell said the speed at which researchers are developing a vaccine to combat COVID-19 is nothing short of a miracle, but sticking to the clinical science behind the advancement is key for an effective and safe vaccine - and that takes time.“The stated goal that I saw by the CDC and/or FDA of wanting a vaccine that shows at least 50% protection and six months of safety data, that takes time,” he said. “We need a chance to show the safety profile of any new vaccine under the parameters of following the best science that we could follow.”Mitchell understands the process involved in developing a vaccine.More than 20 years ago, he was an investigator in several pediatric clinical trials. Many of the vaccines that came out of his lab are still used in children today.While there are still growing concerns about vaccines, the benefits outweigh the risks.“The flu vaccine clearly saves lives, clearly prevents illnesses, but it’s not 100% protective either, but we know it does have benefits,” Mitchell said. “The advantage there is the flu vaccine has been out for decades and we know its safety profile.”Similar to the rapid speed of developing a COVID-19 vaccine, Mitchell said a vaccine for H1N1, better known as the swine flu, was quickly put on the market.“The difference is, we already had decades of history of flu vaccines and their safety, so all that happened was developing the same flu vaccine that was protective against a different strain,” he said. “That’s a different ballgame than starting a vaccine against a totally different virus.”While the research continues, the fight against COVID-19 is far from over.According to Mitchell, the spread of the virus decreases when you reach heard immunity where enough of the population is immune.This story was first reported by Antoinette DelBel at WTKR in Norfolk, Virginia. 2363

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