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WASHINGTON, Sept. 14 (Xinhua) -- Controlling diabetes may someday involve mining stem cells from the lining of the uterus, Yale School of Medicine researchers report in a new study published Wednesday in the journal Molecular Therapy. The team treated diabetes in mice by converting cells from the uterine lining into insulin-producing cells.The endometrium or uterine lining, is a source of adult stem cells. These cells generate uterine tissue each month as part of the menstrual cycle. Like other stem cells, however, they can divide to form other kinds of cells.Led by Yale Professor Hugh Taylor, the researchers bathed endometrial stem cells in cultures containing special nutrients and growth factors. Responding to these substances, the endometrial stem cells adopted the characteristics of beta cells in the pancreas that produce insulin. Over the course of a three- week incubation process, the endometrial stem cells took on the shape of beta cells and began to make proteins typically made by beta cells. Some of these cells also produced insulin.After a meal, the body breaks food down into components like the sugar glucose, which then circulates in the blood. In response, beta cells release insulin, which allows the body's cells to take in the circulating glucose. In this study, Taylor and his team exposed the mature stem cells to glucose and found that, like typical beta cells, the cultured cells responded by producing insulin. The team then injected diabetic mice with the mature, insulin-making stem cells. The mice had few working beta cells and very high levels of blood glucose.Mice that did not receive the stem cell therapy continued having high blood sugar levels, developed cataracts and were lethargic. In contrast, mice that received the cell therapy were active and did not develop cataracts, but the animals' blood sugar levels remained higher than normal.The Yale team's findings suggest that endometrial stem cells could be used to develop insulin-producing islet cells, which are found in the pancreas. These islet cells could then be used to advance the study of islet cell transplantation to treat people with diabetes.Taylor said in a statement that the next step in the research will be to verify how long this treatment remains effective.
BEIJING, Sept. 26 (Xinhua) -- Nobel laureates on Monday cast doubt on a European experiment that purportedly demonstrated the ability of neutrinos to move faster than the speed of light.They made the remarks in Beijing prior to a forum for Nobel laureates."I'm willing to bet money that it's not correct," said Professor George Smoot III, winner of the 2006 Nobel Prize in Physics and a professor at University of California, Berkeley, referring to an experiment result claiming that particles apparently travel faster than light.The experiment reported an anomaly in the flight time of neutrinos, or electrically neutral subatomic particles, from the European Center for Nuclear Research (CERN) in Switzerland to a laboratory located 730 kilometers away in Italy.Particles were clocked transmitting at a speed of 300,006 kilometers per second, about 60 nanoseconds faster than the speed of light.Smoot said that the claims "did not make sense" and should be verified by other scientists first."There are many distortions in physics. You have to have a very high standard to see if something is truly correct," he said.The unverified findings were published on Sept. 22 in the scientific journal Nature. European researchers working in a team called OPERA (Oscillation Project with Emulsion-Racking Apparatus) projected masses of neutrinos from CERN and then collected the particles using a massive detector in Gran Sasso, south of Rome.Other scientists, as well as the OPERA team themselves, have voiced doubts regarding the experiment's results.The findings, CERN claims, could pose far-reaching potential consequences once verified.If correct, the results would bring Einstein's theory of special relativity into question. Under this theory, a physical object cannot travel faster than the speed of light in a vacuum."If really it is right, we have to rethink everything we know," said Chris Llewellyn Smith, former director of CERN.Smith claimed the unprecedented discovery was too exceptional to find proof."If somebody makes a very exceptional claim, then very exceptional proof would need to come from another experiment, saying the same thing. But we don't have the other thing," Smith said.Carlos Rubbia, a Nobel Laureate who won the prize for physics in 1984, is in charge of a team of more than 100 scientists at CERN."What it is pretending to find, in my view, is unbelievably surprising," Rubbia said."Frankly, I have the feeling that this is still a very experimental consideration," Rubbia said.He also believes that revealing the findings to the public was a mistake as it remained an experimental process and no conclusion could be drawn without the results of another experiment.Despite the possibility of verification, Einstein's special theory of relativity will remain valid."I will be very, very surprised that, at last, Einstein will not be the winner," Rubbia said.To achieve a breakthrough, Rubbia has urged for more joint cooperation on verifying the test results. International cooperation on this issue "is a must.""It requires coordination from all nations," said Rubbia.The 2011 Nobel Laureates Beijing Forum will be held from Sept. 28 to 30 under a theme of "innovation and development."
UNITED NATIONS, June 9 (Xinhua) -- China on Thursday called for governments, organizations and individuals to take active actions, enhance solidarity and establish joint prevention and treatment mechanism to deal with AIDS.Yin Li, vice Health minister of China made the remarks as he addressed the United Nations High-Level Meeting on HIV/AIDS held here."As a responsible developing country, the Chinese government has actively fulfilled its commitments in achieving universal access to AIDS prevention and treatment, eliminating social discrimination, and ensuring rights to prevention, treatment and care of people living with HIV/AIDS and their families," he said.Thanks to the efforts over the years, the spread of AIDS epidemic in China has slowed down, the morality rate considerably decreased and life quality of people with HIV/AIDS has significantly improved, Yin added.In order to achieve the goal of zero new HIV infections, zero discrimination and zero AIDS-related deaths defined by the joint UN Program on HIV/AIDS (UNAIDS), China called for all countries, organizations and persons to be mobilized, further enhance solidarity and clearly define responsibilities and establish a joint prevention and treatment mechanism.Yin said that in the face of the common challenge of HIV/AIDS, the developed and developing countries must assume shared responsibilities."The developed countries should further provide developing countries with generous, unconditional financial and technical support. The developing countries should give the same priority to AIDS control as economic development, explore the models of prevention and treatment consistent with their national conditions, " he said.In addition, the private sector and relevant organizations should assume more responsibilities. On one hand, efforts should be made to mobilize more resources in better implementing prevention, treatment and care measures; on the other hand, multinational drug manufactures should reduce drugs and testing equipment prices through technology transfer, contract manufacturing and reduction of monopoly profits in order to provide universal access to treatment services, according to Yin.Yin stressed that the Chinese government would strengthen its working mechanism, enhance coordination across sectors and participation by the entire society, continue to actively participate in global fight against AIDS, assume its responsibilities and obligations so as to make contribution to achieving the goal of global AIDS control.
BERLIN, June 8 (Xinhua) -- The deadly strain for the E. coli outbreak was found again on cucumbers, authorities of German state Saxony-Anhalt said on Wednesday. The strain O104 was found on the scraps of cucumbers in a dustbin in the eastern city of Magdeburg, said State Health Minister Holger Paech.The dustbin belongs to a family in which three members have been ill. Paech said. The father only suffered a slight stomach upset, while the mother was once treated at a hospital and is now released. Their daughter is suffering from hemolytic-uremic syndrome (HUS), a serious complication from the infection of E. coli.However, experts were not clear about how the bacteria came to the cumbers, which have been in the dustbin for a week and a half."It is not clear and we are not able to determine how it reached there." Paech said.German authority first detected such bacteria from Spanish cucumbers on May 26, which has been overthrown by the laboratory tests in Hamburg last Tuesday.On Sunday, German State Lower Saxony issued a warning on bean sprouts as a possible source for the outbreak, which was proven to be negative on Monday.The German government has faced increasing criticism from abroad and at home for dealing with this crisis, as it has wrongly blamed the source of the infection for twice and there is a lack of coordination between different research institutes on the outbreak.John Dalli, European Union Health Commissioner, was quoted by local daily Die Welt saying "we have to rely on the experience and expertise across Europe, and even outside Europe."The Max Planck Institute for Infection Biology in Berlin also called for a federal government representative to coordinate the various government agencies which are dealing with the crisis.A federal government representative could increase cooperation between ministries and reduce mixed messages from the government, said director Stefan Kaufmann.On the same day, Germany's national disease control center, the Robert Koch Institute, said the number of infection has shown an overall decreasing trend but it is still uncertain whether the decline is due to people staying away from vegetables or to the waning of the source of infection.Until Wednesday, 25 deaths have been reported while the infection cases have increased more than 2,600 in 12 countries around the world.