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A final analysis of a COVID-19 vaccine candidate produced by Pfizer and BioNTech shows that the drug is 95% effective in preventing the coronavirus, and the companies say they hope to apply for Emergency Use Authorization within "days," the company reported Wednesday.The announcement is an improvement from an initial analysis released by the company just over a week ago that showed the drug to be 90% effective. Those results were released when it had been confirmed that 94 participants in the trial who received a shot had contracted COVID-19, and only 10% of those participants who contracted the virus had actually received the vaccine. Updated information now shows that 170 people who participated in the trial have contracted COVID-19, which crosses the threshold for final analysis. Of those participants, 162 received a placebo shot. Of the 20,000 participants who received the vaccine, just one has developed a severe case of COVID-19. The other seven people who received the vaccine and caught the virus are only experiencing mild symptoms.Pfizer also added that the vaccine has proven to be 94% efficient in older people — a welcome sign, given that the virus tends to present more severe symptoms in elderly patients.Pfizer's trial included about 40,000 participants, half of which received the vaccine, and the other half which received the placebo. The vaccine requires two shots, which need to be taken 28 days apart.The company added that there have been no safety concerns with the vaccine. In a randomized survey of 8,000 participants, only 2% reported suffering severe fatigue, and only 4% reported suffering severe headaches. Those who say they suffered side effects only experienced them briefly after vaccination.Wednesday's announcement means Pfizer is on track to shatter records for vaccine development, a process that typically takes several years.Pfizer and BioNTech already have their vaccine candidate in production, meaning it will be ready for distribution as soon as the Food and Drug Administration grants Emergency Use Authorization.Pfizer's announcement comes days after an initial analysis of a Moderna-produced vaccine was also shown to be 95% effective. Several other companies also have a COVID-19 vaccine in the works, something that health officials say is important for logistics and safety. 2347
A California surgeon who had been accused of drugging and raping two women was charged with five more cases Wednesday, bringing the total number of alleged victims to seven.Grant Robicheaux, 38, pleaded not guilty to the charges.His girlfriend, Cerissa Riley, 31, was also charged in three additional cases, and pleaded not guilty."We unequivocally deny all allegations of nonconsensual sex and absolutely deny any allegations that we have ever secretly drugged anyone for the purpose of having sex with them," the couple said in a statement.They said they passed polygraph tests and knew about the investigation since January. "We didn't flee, we didn't move, and we didn't go into hiding. ... We look forward to getting our lives back."Orange County prosecutors also added kidnapping charges against Robicheaux and Riley. 831

A man picking up passersby flagging him and his buggy down for a ride is calling his service "Amish Uber."The service is not affiliated with the actual Uber ride-sharing service, but it has been popular in the town of Colon, Michigan, where driver Timothy Hochstedler is using a horse and buggy to cart folks around.Hochstedler has a sign on his buggy that says each ride is and he was offering rides during the town's recent 81st annual Abbott's Magic Get Together festival.WWMT television station talked with people who paid for rises in the buggy, and they said the experience was unique and fun. 626
A man is hospitalized, but expected to survive, after his girlfriend struck him with her car following a domestic argument, according to police in Port St. Lucie, Florida.The incident happened in the 1900 block of W. Dunbrooke Circle.Police said the man got out of the car and began walking down the street and the woman then dropped off her baby at their house, drove back to where the man was walking and hit him.Video posted by police shows crime scene tape around a car which appears to have a big dent in the hood and a shattered windshield.The man, described as the woman's 24-year-old live-in boyfriend, was airlifted to a hospital with head trauma. He was undergoing surgery late Wednesday afternoon.Police did not identify either person but said the investigation continues. “It sounded like a car hitting a shopping cart," said Lance Chmura who lives just across the street from the crash scene. He was making breakfast around 9 a.m. when he heard the impact and ran out to help.“I went down, grabbed his hand and stabilized him because he was starting to thrash around a bit," said Chmura.The impact of the crash was so intense it sent the man flying 35 yards down the street.“She (the girlfriend) then left the scene, drove back home. Her relative got in car and came back to the scene," said Master Sgt. Frank Sabol with Port St. Lucie Police.The victim’s grandmother would not reveal what the girlfriend said to her immediately after the crash, but said the couple had a good relationship and had just moved down here last month. She said she thinks this was an accident.“I think they were just playing around and didn’t realize the severity of it," said the grandmother.“The initial investigation determines she was on the wrong side of the road when he was struck," added Sgt. Sabol.Right now, it’s being investigated as a case of domestic violence. No arrests have been made. 1948
A family is hoping to locate their fallen soldier's American flag after it was stolen from their truck.Shawn Marceau told FOX 12 his truck was broken into in Yakima, Washington and inside was an American flag that belonged to his son, Joe, who was killed while serving in Afghanistan.He said the signatures of his son and two other fallen soldiers are displayed on the flag."The significance to anybody is really nothing, but to us, it is so personal because it's their last signatures in their lives,” said Marceau. “And I think that is what makes it so important to us. It is part of our son and he had it there with him when he was killed"Marceau hopes someone will find the flag and return it and said there will be no questions asked if returned. 765
来源:资阳报