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SAN DIEGO (KGTV) — UC San Diego Health and three other UC Health medical centers will begin to recruit participants for an antiviral drug being tested to treat the novel coronavirus.The medical system will start "phase II" clinical trials for the antiviral drug remdesivir. The drug has "shown activity in animal models and human clinical trials of SARS-CoV, MERS-CoV, Ebola, Marburg and other viruses," according to UCSD Health.RELATED: San Diego hospitals start drives for personal protective equipmentRemdesivir is not currently approved for the treatment of any infection by the FDA, but is currently undergoing trials for treating multiple viruses, including COVID-19.“With this type of adaptive study design, if remdesivir proves to be safe and active, the clinical trial may be rapidly adapted to remove the requirement for a placebo arm and add a treatment arm that includes other promising antiviral or other investigational drug to compare with the activity of remdesivir," said co-principal investigator Constance Benson, professor of medicine at UC San Diego School of Medicine and an infectious disease specialist at UC San Diego Health.RELATED: Nurse urges people to turn over N95 masks to San Diego hospitalsUC San Francisco, UC Irvine Health, and UC Davis Health are also participating in the trials. The trial is projected to run until April 1, 2023 and involve 440 participants. 1404
SAN DIEGO (KGTV) — Two men convicted of leading a home-invasion robbery spree with five other people were sentenced to prison terms Friday.A judge sentenced 26-year-old Thomas James Smith to 85 years plus 50 years to life in prison and 22-year-old Aaron Rico III to 35 years plus 25 years to life in prison for their roles the series of violent break-ins.Smith and Rico were convicted of conspiracy to commit burglary, robbery, burglary and sexual assault in June. The violent crime spree began on January 23. The series of crimes included breaking into homes, tying up and assaulting homeowners, and in one case, sexually assaulting a woman. RELATED: 680
SAN DIEGO (KGTV) -- We know the importance of wearing a mask to protect the nose and mouth from the novel coronavirus, but some new research is raising questions about whether the general public should wear goggles, glasses or a shield to protect their eyes.The CDC already urges healthcare workers to wear eye protection. The agency updated its guidance in July, encouraging even healthcare workers in low-transmission environments to wear eye protection when it was previously listed as “optional.”Experts think the nose is still the main entry point for the virus because of the mechanics of breathing, but the surface of the eye is lined with the same mucous membrane to which the virus likes to bind.Animal studies have shown SARS-CoV-2, the virus that causes COVID-19, can enter through the eyes and there have been viral particles detected in human tears, but there’s no clear-cut data so far showing the eyes are a major entry point, said ophthalmologist Dr. Annie Nguyen at the USC Roski Eye Institute.However, some observational studies have suggested protecting the eyes may lower the risk of infection.In June, a study in the Journal Lancet suggested face shields, goggles and glasses could lower the risk of infection from 16 percent to 6 percent.Another study published this month suggests that simply wearing eyeglasses could help.Researchers examined 276 hospitalized patients in Suizhou, China. Based on trends in that region, they expected about 31 percent of the patients would wear eyeglasses. Instead, just 5 percent of the hospitalized patients wore glasses.The researchers noted the observational study had limitations, but theorized that eyeglasses may offer a protective barrier against the virus.“I wouldn’t be quick to make the recommendation for everyone to run out and wear glasses,” Dr. Nguyen said.An editorial published alongside the eyeglasses study urged caution. “Although it is tempting to conclude from this study that everyone should wear eyeglasses, goggles, or a face shield in public to protect their eyes and themselves from COVID-19, from an epidemiological perspective, we must be careful to avoid inferring a causal relationship from a single observational study,” wrote Dr. Lisa Maragakis at Johns Hopkins University School of Medicine.Experts say more evidence is needed because urging people to wear eye protection could have harmful side effects, like causing the wearer to inadvertently touch their face more frequently.“If there is additional evidence that builds up, then that’s the point that we change guidelines,” said Dr. Christian Ramers of Family Health Centers of San Diego.“People have had whiplash from things changing and going back and forth,” he added, citing the change in guidelines on face coverings.Still, some experts say people with underlying conditions should consider adding eye protection, as long as they’re careful not to touch their face.Doctors have suggested that people who wear contact lenses might want to switch to eyeglasses to cut down on the number of times they touch their eyes, but Dr. Nguyen said there’s no hard data yet showing contact lens-wearers are at greater risk from the virus. 3184
SAN DIEGO (KGTV) -- While the San Diego Padres lost to the Los Angeles Dodgers Tuesday night in Game 1 of the National League Division Series, fans were thankful to be able to participate in the action alongside other San Diegans.While much of the Friar Faithful couldn’t make it to Texas to cheer on the Padres, the playoff excitement was still felt downtown, and for some, that was enough.“Unfortunately, you can’t watch it live, but to be surrounded with a group of people that are all watching it and all really excited, it’s pretty magical,” said Andrea Durkee, a resident of downtown and Padres fan. “I think we all needed something just happy and exciting and to look forward to, and this is absolutely the best thing we could have downtown.”Some fans watched the first game in the best-of-five series from Petco Park’s Tailgate Lot, which was transformed into a drive-in style viewing party.“I have season tickets actually, and we weren’t able to go this year, which is a huge bummer, but we’ve made the best out of it,” said Catie Vance. “We’re excited that we got to do this, at least.”Spectators on the other side were just as excited.“Grew up in LA, my grandfather had season tickets, I’ve probably seen 100 Dodger games at Dodger stadium I haven’t seen them win the world series yet, I’d love to see that, but I guess if someone has to go and the Padres do go, there’s worse things that can happen in life,” said Michael Martin, a Dodger’s fan.Facial coverings were required for all fans outside of their vehicles, and vehicles were spaced 20 feet apart to encourage social distancing. 1606
SAN DIEGO (KGTV) - When William Hauf looks out his kitchen window, he sees rows of patio furniture that won't fit anywhere else."I just had to leave that stacked up out there," he says. "And I've got boxes of books in my garage right now that are unopened and brand new. Books that I haven't even seen yet."They're leftovers from Hauf's former, more successful life.In March, he sold his estate in Santaluz for million. Hauf had to sell it after losing millions of dollars himself in real estate and travel investments. RELATED: Making it in San Diego: Energy super-savers see summertime successHe's now renting a home in Carlsbad. Today, Hauf says he can't write a check for ,000. It's a key number because that's what San Diego Gas and Electric says he still owes them from his Santaluz home. Hauf got that roughly ,000 bill in March - an annual balance correction because the Santaluz home had solar, meaning he didn't have to pay monthly. SDG&E is now threatening to cut the electricity to his new home in Carlsbad if he doesn't pay the balance. "It's a nightmare, and I have no power to be able to confront this," Hauf said. SDG&E checked Hauf's meter in 2018, after a roughly ,000 annual bill. He said he hoped they would do more at the time. "They didn't investigate, they didn't identify, they didn't do an audit, they didn't do any of that," he said. Then came the ,000 whopper in March. In a statement, SDG&E noted that Hauf's bill worked out to 2 a month for the 7,600 square-foot Santaluz home. The company said it found no issues with the meter and that something in the home was being left on for long periods of time. SDG&E says it has advised Hauf to make sure his pool pump was not left running but Hauf said there's a big problem with that advice."There's no pool in the house," he said. "There's no swimming pool, there's no heater, there's no air conditioning."In other words, Hauf can't pinpoint what caused his annual bill to get to ,000 dollars, and he doesn't think SDG&E can either. A spokesman for SDG&E said the utility isn't always privy to the types of appliances customers have, but reiterated that Hauf's meter was functioning normally during that time. This is the utility's full statement:This solar customer received an annual true-up bill of ,111.46 for twelve months of energy use at his 7,600+ sq. foot home. If you average that out it would be approximately 2 per month. Over the past several years we have spoken with this customer regarding increasing energy usage and other billing related questions. In the spring of 2018, we tested the electric meter and found no issues. In a review of his March 2018 bill, we indicated that something in the household was turned on and left on for periods of time. The customer stated he would follow up with pool maintenance person to ensure the pump was not left running. 2904