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Holidays will look different this year for many Americans, with dinners outside, social distancing, or passing on family gatherings altogether. But several companies developing rapid at-home COVID-19 tests are hopeful that won't be the case next year. The goal is to make inexpensive, easy-to-use COVID tests that can deliver results in minutes, just like a pregnancy test. "For people to feel comfortable to associate with friends or family, there needs to be a testing methodology ideally that can be performed at home," said Tony Lemmo, CEO of the manufacturing company BioDot.The company's technology is being used by over 70 manufacturers worldwide making COVID-19 antigen, antibody, and PCR tests. Their automated platforms dispense nanoliter/picoliter amounts of reagent onto the tests accurately and fast.Lemmo says just one of their systems can support the production of roughly 100 million COVID-19 tests per year, helping to make high-volume production possible.“We knew we were going to be called on by customers to manufacture more equipment to provide them the ability to manufacture more tests," said Lemmo. To meet customer demand, BioDot increased staffing and built a new facility, compressing production time from months to weeks. The FDA recently authorized the first rapid at-home test that can deliver results in 30 minutes, eliminating the need for a lab to test the sample. But the molecular single-use test will only be available to patients with a doctor's prescription who are suspected of being infected with COVID-19.Companies developing tests hope the FDA will soon authorize another at-home testing tool: the rapid antigen test.These inexpensive tests provide results within minutes, and companies developing them say millions could be sold without a doctor's referral.“From what we’re hearing, it’s really just a matter of possibly months before there’s at least sufficient data to be able to support an at-home use of a test like an antigen test," said Lemmo.Lemmo says if authorized by the FDA, manufacturers could make millions of these tests in a matter of months. But antigen tests are less accurate, and the FDA wants to ensure they'll be simple enough for people to use at home. There are also concerns over how the data will be reported to health authorities. “I think any at-home testing or massive rollout of a test into the communities needs to be done very carefully and with a lot of education around it," said Clinical Lab Director Melissa Miller. Dr. Miller is a professor of pathology and laboratory medicine at the University of North Carolina Chapel Hill and Medical Director for the Clinical Microbiology Lab for the Medical Center.She worries the inaccuracies of these tests could eventually lead the public to lose trust in all testing. “Even at 98 percent specificity, which is very, very high. That means you’re going to have a false positive two out of every 100. If you started testing a hundred million people, this is millions of people who have a false-positive test," said Dr. Miller. She says this could lead to healthy people isolating and missing work or school unnecessarily, and false-negative results could give people a false sense of security. “These rapid antigen tests were pushed out to skilled nursing facilities; this is a very high-risk patient population. This is actually where you want a very accurate test," said Dr. Miller. She says it’s unclear how well antigen tests detect the virus in asymptomatic patients but agrees more data is needed to figure that out.“It might make more sense for K-12 schools, or even college settings, where there’s less risk for a poor outcome if you have a false positive or a false negative," said Dr. Miller. But with a growing demand for convenient at-home testing, manufacturers are hopeful that in the months ahead, the FDA will soon open the door to new solutions. 3889

Good people of America, the dream is still alive.There was no winner in Tuesday's Mega Millions lottery drawing.That means the jackpot for Friday's drawing is now at least 0 million, or a cash lump sum of 8.6 million, and the number will just keep climbing until some lucky person (who will most likely not be you) hits it big. It will be the largest jackpot in the game's history and the second largest in the US lottery jackpot history.The Mega Millions jackpot beat its own record once again after no ticket matched all the six numbers in the drawing Tuesday night. The winning numbers on Tuesday were 69, 45, 61, 3, 49, and the Mega Ball was 9.Friday's Mega Millions along with the next Powerball jackpot are worth more than a cool billion dollars.The reason these jackpots have ballooned to such monstrous proportions is because, well, no one has won in a while. According to a release from Mega Millions, the last Mega Millions jackpot was won July 24, netting 11 co-workers a combined 3 million. The last Powerball jackpot, which totaled 5.6 million, was won August 11 by a man in Staten Island, New York.Believe it or not, this week's combined billion-dollar haul is not the biggest prize in the lottery's history. That honor goes to a 2016 Powerball jackpot, which clocked in at .586 billion (although it was shared by three winners).Of course, the actual amount you'll win is considerably less than a billion dollars, not just because of taxes and annuities and fine print things. The amount you will win is likely FULLERTON (CNS) - A Compton couple facing criminal charges stemming from a brawl at Disneyland that was captured on video that went viral failed to appear in court this week for arraignment.Andrea Nicole Robinson, 40, and her husband, Daman Petrie, 44, were scheduled to be arraigned on Monday, but they did not show up for the hearing, according to court records obtained by City News Service.It's not clear what authorities will do to compel the defendants to appear in court, but there are no more hearings scheduled so far.RELATED: Three people charged in Disneyland brawl that was caught on videoRobinson's 35-year-old brother and co-defendant, Avery Desmond-Edwinn Robinson, is due in court Sept. 30 for a pretrial hearing at the North Justice Center in Fullerton.Avery Robinson faces the most serious charges of the three defendants. He is charged with one felony count each of domestic battery with corporal injury, assault with force likely to produce great bodily injury on his girlfriend and assault with a deadly weapon and two counts of criminal threats, along with five counts of battery and four counts of child abuse and endangerment, all misdemeanors.Robinson's sister is charged with four misdemeanor counts of battery for allegedly attacking her brother, his girlfriend and a Disneyland security guard, and a misdemeanor count of assault on her brother's girlfriend. She faces 2 1/2 years in jail if convicted.Petrie is charged with one count of battery on his brother-in-law's girlfriend, who was punched in the face during the July 5 scrum, and faces up to six months in jail if convicted, according to prosecutors.It's unclear what touched off the fight, which broke out in Toontown and sprawled out onto the Main Street in the famous theme park, but several Disneyland visitors tried to stop it, prosecutors said. One theme park guest put Avery Robinson in a chokehold, prosecutors said, and one of the children with the family was carried away from the brawl.When security guards asked the family to leave, there was more violence, prosecutors allege. Avery Robinson is accused of attempting to hit a security guard with his vehicle as he drove away and threatening to kill his sister and Petrie as he allegedly simulated having a gun in his hand, prosecutors said. 2297, because the odds of winning either jackpot are one in several hundred million.Sure sure, someone needs to win eventually, we know. But it's not going to be you.**OK, almost certainly not. But cheer up! There are often secondary prizes to these huge drawings that can be worth millions of dollars, and a shocking amount of them go unclaimed -- probably because people get too focused on the biggest possible way to win. 1975

GLENDALE, AZ — It's official: The San Francisco 49ers will play their next two home games in Arizona after local COVID-19 restrictions prevented them from playing at their home field."The San Francisco 49ers have come to an agreement with the National Football League and Arizona Cardinals which allows the 49ers to host their Weeks 13 and 14 home games against the Buffalo Bills and Washington Football Team at State Farm Stadium in Arizona," the 49ers said Monday in a statement.Over the weekend, California's Santa Clara County announced a number of new COVID-19 restrictions, which banned all sports — professional, collegiate, and youth — and required people to quarantine for two weeks if they traveled 150 miles away.Levi's Stadium, home to the 49ers, is located in Santa Clara County."The Cardinals organization, State Farm Stadium and League officials have been supportive and accommodating as we work through the many logistical issues involved in relocating NFL games," the Arizona Cardinals said in a statement.The Cardinals will host the Los Angeles Rams at State Farm Stadium on Sunday, Dec. 6. Previously, the team announced that no fans aside from a limited number of staff and players' families would be allowed inside the stadium.The 49ers will host the Buffalo Bills in Arizona on Monday, Dec. 7, and will then host the Washington Football Team there on Dec. 13.This story was originally published by KNXV in Phoenix, Arizona. 1453

GENEVA, Ohio — As the service industry struggles due to the COVID-19 pandemic, business owners and employees face a new stressor: enforcing mask mandates and seating requirements at bars and restaurants.It’s no secret that adults don’t enjoy being told what to do, especially if they feel enforcement infringes on their personal space or choices. Behavioral therapists say there is a complex science that explains why some adults have reverted to infantile behavior during the pandemic.In recent weeks, there have been several incidents across in the country about high-profile disputes over masks — some of which have grown violent. The owner of a northeast Ohio winery said such a dispute led to property damage over the weekend.“We did have one incident where a customer punched a hole in the drywall in the men’s room at 7 p.m. on Saturday night,” said Gene Sigel, the owner of South River Vineyard.Sigel said in 20 years, the winery has never had any sort of property damage, but new state-mandated restrictions when visiting the vineyard appear to have some customers on edge.“We’re used to enforcing guidelines from the governor,” Sigel said. “But at the same time, asking people to sit down or put on a mask is a whole new range of imposition on people’s personal space.”While Sigel said the hole in the wall is a fairly inexpensive fix, his employees feel the behavior speaks to the way service industry workers are being treated by customers during the COVID-19 pandemic.“It certainly played into the tension,” Sigel said. “For whatever reason, somebody felt that the only place that there wouldn’t be a surveillance camera was in the restroom and that was a good place to leave a comment on their feelings as to the requirements here.”Behavioral therapists at the Cleveland Clinic report there’s scientific data to back up why adults behave this way in stressful situations. “Rebel psychological reactance” refers to the brain’s reaction to a threat to freedom or personal choices.Therapists believe those frustrations sometimes cause people to abandon common sense and behave erratically, even when safety is concerned.Sigel said he wants to remind customers to be patient with staff when visiting the vineyard and other businesses and added that employees are all doing the best they can to provide an enjoyable experience despite the new restrictions.“None of us have a lot of options of places to go. We can’t jump on a plane and fly somewhere,” Sigel said. “We can’t go across the country necessarily in our vehicle, so there’s a greater infrastructure demand at our local events.”This story was originally published by Emily Hamilton on WEWS in Cleveland. 2680

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