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SAN DIEGO (AP) — A California tribe whose ancestral lands span across the U.S.-Mexico border is suing the Trump administration to block construction of a section of border wall that the Kumeyaay people say is desecrating sacred burial sites. The La Posta Band of Diegueno Mission Indians filed the lawsuit in federal court in San Diego on Tuesday seeking to temporarily halt construction of the wall until the tribe can protect its religious and cultural heritage. La Posta is one of 12 bands of the Kumeyaay people. The tribe wants its members to be able to monitor work and interrupt it to recover human remains and cultural items uncovered during construction. Federal officials did not immediately respond to a request for comment. 743

SAN DIEGO (AP) — Fans at the Holiday Bowl between No. 19 Iowa and No. 22 Southern California will be asked to do the “Iowa Wave” directed at patients in a children’s hospital in Iowa City as well as representatives from two children’s hospitals in Southern California who will be at the game on Dec. 27.The wave will replicate what has become a game-day salute at Hawkeyes home games to patients and family members at the University of Iowa Stead Family Children’s Hospital.The salute started on Sept. 2, 2017, when more than 70,000 fans stood at the end of the first quarter and waved to patients and families in the children’s hospital, which rises above Kinnick Stadium. The patients and families waved back. Ever since, players and coaches from both teams, game officials, and others working the games also join in the wave.RELATED: USC to face Iowa in Holiday BowlHoliday Bowl parade 2019: Where to watch, park downtownAt the end of the first quarter at the Holiday Bowl, everyone in the stadium will be encouraged to stand and wave toward the east end video board that will feature the children and families at the Iowa City hospital. Sitting below the video board will be representatives from Rady Children’s Hospital in San Diego and individuals from Children’s Hospital Los Angeles.FS1 plans to cover the event during the game broadcast so the children in Iowa City will see it.”I’ve been to a lot of college football games all around the country in my nearly 30 years with the bowl game,” bowl CEO Mark Neville said. “Without question, the Wave at Kinnick Stadium was the most incredible thing I’ve ever experienced at a game. I’m so grateful that our fans attending next week’s Holiday Bowl will get to participate in college football’s best and most moving tradition.“This might very well end up being the coolest moment in our bowl game’s history,” Neville said.Iowa is making its first trip to the Holiday bowl since 1991. 1944

SAN DIEGO (CNS) - A COVID-19 vaccine trial sponsored by drugmaker Johnson & Johnson is slated to get underway soon in San Diego, and will include an estimated 2,000 participants at UC San Diego Health, it was announced Thursday.Up to 60,000 participants will be recruited from 10 different countries around the world as the San Diego portion of the trial, dubbed ENSEMBLE, gets underway Oct. 7, according to UCSD.The efficacy, safety and immunogenicity of the drug Ad.26-COV2.S will be tested via a randomized, double-blind, placebo-controlled study, in which half of the participants receive a single-dose injection of the vaccine and the other half receive a placebo. All participants -- who must be 18 years of age or older and in reasonably good health -- will be monitored for signs of infection and COVID-19 over the next two years, according to UCSD.Researchers are particularly interested in recruiting participants at increased risk of SARS-CoV-2 infection due to where they live, their age or personal circumstances, such as working in essential jobs like first responders, health care, maintenance, construction, grocery stores or assisted living facilities.The San Diego trial will also emphasize participation from the region's underserved communities, as communities of color have shown higher rates of COVID-19-related hospitalization and/or death.UCSD cited data from the county showing measurably higher infection rates in the South Bay, including in Chula Vista, Imperial Beach and National City.Susan Little, professor of medicine at UC San Diego School of Medicine and principal investigator of the UC San Diego trial, said, "Many communities of color are experiencing higher rates of hospitalization related to COVID-19 than are observed in white, non-Hispanic people. It is important that these communities are represented in COVID-19 vaccine clinical trials so that we understand if the vaccine will work well within these groups."For more information about participating in the trial at UC San Diego, go to www.covidvaccinesd.com or call 619-742-0433. 2087

SAN DIEGO (CNS) - A 59-year-old woman suffered a fractured back when she was struck by a hit-and-run motorist in the Clairemont Mesa West community of San Diego, a police officer said Sunday.The woman was crossing westbound in the south crosswalk when she was hit a little before 6:25 p.m. Saturday by a vehicle that had been going westbound on Derrick Drive and made a left turn to southbound Genesee Avenue, said Officer Robert Heims of the San Diego Police Department.Police had no description of the vehicle or the motorist. Paramedics rushed the woman to an area hospital with a fractured back, Heims said.Anyone who saw the crash was asked to call Crime Stoppers at (888) 580- 8477. 696

SAN DIEGO (CNS) - A 44-year-old pedestrian was hit by a car and seriously injured in Mission Valley Saturday, police said.The unidentified man was walking in a crosswalk at about 5 a.m. on 2300 Camino Del Rio North when a 57-year-old driver of a Ford Explorer traveling northbound on Qualcomm Way turned eastbound and the vehicle hit the pedestrian.The man walking in the crosswalk suffered a possible skull fracture, several facial fractures and internal injuries. His injuries are considered to be life-threatening, police said. 538