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New York, Sept. 23 (Xinhua) -- A Chinese scientist was presented a prestigious U.S. award on Friday for the discovery of artemisinin, a drug therapy for malaria that has saved millions of lives across the globe, especially in the developing world.Pharmacologist Tu Youyou, 81, became the first scientist on the Chinese mainland to win Lasker Award, known as "America's Nobels" for their knack of gaining future recognition by the Nobel committee.Tu, a scientist at the China Academy of Chinese Medical Sciences in Beijing, pioneered a new approach to malaria treatment that has benefited hundreds of millions of people and promises to benefit many times more. By applying modern techniques and rigor to a heritage provided by 5000 years of Chinese traditional practitioners, she has delivered its riches into the 21st century."Not often in the history of clinical medicine can we celebrate a discovery that has eased the pain and distress of hundreds of millions of people and saved the lives of countless numbers of people, particularly children, in over 100 countries," Lucy Shapiro, a member of the award jury and professor of Stanford University, said while describing Tu' s discovery.Shapiro said the discovery, chemical identification, and validation of artemisinin, a highly effective anti-malarial drug, is largely due to the "scientific insight, vision and dogged determination" of Professor Tu and her team. She thought Professor Tu's work has provided the world with arguably the most important pharmaceutical intervention in the last half century."The discovery of artemisinin is a gift to mankind from traditional Chinese medicine," Tu said while receiving the award. "Continuous exploration and development of traditional medicine will, without doubt, bring more medicines to the world."
RIO DE JANEIRO, Sept. 26 (Xinhua) -- Rio de Janeiro has the highest level of air pollution in Brazil, and is more polluted than many other world metropolis like New York, London and Paris, a World Health Organization (WHO) study said Monday.According to the study, which was carried out in 91 countries and regions, the air in Rio's metropolitan area contains 64 micrograms of fine particulate matter per cubic meter, over three times the upper limit set by the WHO, which is 20 micrograms per cubic meter.Despite being larger, having a bigger population and more vehicles, Sao Paulo's metropolitan area has less air pollution, with 38 micrograms of fine particulate matter per cubic meter.According to the WHO, "the largest contributors to urban outdoor air pollution include motor transport, small-scale manufacturers and other industries, burning of biomass and coal for cooking and heating, as well as coal-fired power plants." The organization said that residential wood and coal burning for heating also help increase air pollution, especially in rural areas in the cold months.The WHO expressed concern over air pollution levels in several cities, as some two million people worldwide die annually from conditions resulting from air pollution."Air pollution is a major environmental health issue, and it is vital that we increase efforts to reduce the health burden it creates," said Dr. Maria Neira, WHO's director for Public Health and Environment.According to the study, Ahwaz, Iran, has the most polluted air in the world, with 372 micrograms of fine particulate matter per cubic meter.
SINGAPORE, Sept. 7 (Xinhua) -- Singapore scientists have found possible new ways to treat a type of aggressive breast cancer that is unresponsive to current forms of treatment, local broadcaster Channel NewsAsia reported on Wednesday.The team of scientists at the Genome Institute of Singapore ( GIS) and National University of Singapore (NUS), led by GIS senior group leader Qiang Yu, found that the enzyme EZH2 acts by inhibiting genes that stop the growth of tumors in the body.The insights could open the door to developing more effective treatment for fast spreading breast cancers, especially the estrogen receptor-negative breast cancer that is common all over the world.It was also found that through EZH2, cancer is promoted in the body by activating specific genes that impact breast cancer progression and cancer stem cell self-renewal.Yu said the new understanding on how EZH2 works as a cancer- causing gene in breast cancer has important therapeutic implication."The results suggest that small molecule drugs that block enzyme activity of EZH2 may not work for cancers caused by EZH2's activation genes," Yu said.Currently pharmaceutical companies have been developing drugs only to the block EZH2 enzyme activity so that tumor suppressers can perform their protective role in blocking cancer growth.Researchers said the next step would be to develop biomarkers to identify tumors with EZH2.This step would enable better treatment methods, with one of options being the development of therapies that shut down EZH2 completely and not just inhibit its enzymatic function.The findings have been published on the journal Molecular Cell.
WASHINGTON, Sept. 15 (Xinhua) -- A team of researchers has discovered a planet that orbits around a pair of stars, the U.S. space agency NASA announced Thursday.This is the first instance of astronomers finding direct evidence of a so-called circumbinary planet. A few other planets have been suspected of orbiting around both members of a dual-star system, but the transits of the circumbinary planet have never been detected previously.The team, led by Laurance Doyle of the SETI Institute in California, used photometric data from the NASA Kepler space telescope, which monitors the brightness of 155,000 stars.NASA's Kepler mission has discovered a world where two suns set over the horizon instead of just one. The planet, called Kepler-16b, is the most "Tatooine-like" planet yet found in our galaxy. Tatooine is the name of Luke Skywalker's home world in the science fiction movie Star Wars. In this case, the planet it not thought to be habitable. It is a cold world, with a gaseous surface, but like Tatooine, it circles two stars.They found the binary star system by detecting a system where the stars eclipsed each other from the perspective of the Kepler spacecraft. These stars have two eclipses: A primary eclipse when the larger star is partially blocked by the smaller star and a secondary eclipse where the smaller star is fully blocked by the larger star.But the researchers also noticed other times when the brightness of the two stars dropped, even when they were not in an eclipse position. This pattern suggested that there was likely a third object involved. The fact that these so-called tertiary and quaternary eclipses recurred after varying intervals of time, and were of different depths, indicated that the stars were in different positions in their orbit at each instance. This result showed that the tertiary and quaternary eclipses were being caused by something circling both stars, and not an object circling one or the other star.Measurements of the variations in the timing of all four types of eclipses, resulting from the mutual gravitational interactions of the two stars and the third body, demonstrated that the third object was, indeed, a planet. Their work indicates that the planet is less massive than Jupiter, possibly comparable in mass to Saturn, and that the larger of the two binary stars is smaller than our Sun.Their findings will be published Friday in Science."This discovery confirms a new class of planetary systems that could harbor life," Kepler principal investigator William Borucki said in a statement. "Given that most stars in our galaxy are part of a binary system, this means the opportunities for life are much broader than if planets form only around single stars. This milestone discovery confirms a theory that scientists have had for decades but could not prove until now."
BEIJING, Aug. 22 (Xinhuanet) -- Researchers have discovered how a human egg captures an incoming sperm for fertilization, paving the way to help couples suffering from infertility, according to media reports on Monday.An international team of researchers found that a sugar chain known as the sialyl-lewis-x sequence (SLeX) makes the outer coat of the egg “sticky,” which has proven to be helpful in binding the egg and the sperm.As a result, this observation has filled in a huge gap in the understanding of fertility and provides hope for ultimately helping couples who currently cannot conceive.Scientists and doctors know that a sperm identifies an egg when proteins on the head of the sperm match and bind to a series of specific sugars in the egg’s outer coating. With a successful match of proteins, the outside surfaces of the sperm and egg then bind together before merging, which is then followed by delivery of sperm’s DNA into egg.To identify this molecules, the researchers used ultra-sensitive mass-spectrometric imaging technology to observe and identify which molecules are most likely to be key in the binding process.They experimented with a range of synthesised sugars in the laboratory and found that it is SLeX that specifically binds sperm to an egg.According to the World Health Organisation, infertility affects about 15 percent of reproductive-aged couples around the world and almost one in every seven couples in Britain has problems conceiving a child for various reasons.