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LOS ANGELES, July 18 (Xinhua) -- U.S. scientists have proven that oncogenes can change normal cells into stem-like cells, paving the way to a safer and more practical approach to treating diseases like multiple sclerosis and cancer with stem cell therapy.In a collaborative study, researchers from the Keck School of Medicine of the University of Southern California (USC), and the Children's Hospital of Orange County (CHOC) in California and Good Samaritan Hospital Medical Center in New York have successfully converted human skin cells into brain cells by suppressing the expression of p53, a protein encoded by a widely studied oncogene. This suggests that p53 mutation helps determine cell fate -- good or bad -- rather than only the outcome of cancer.Oncogenes are generally thought to be genes that, when mutated, change healthy cells into cancerous tumor cells.Study findings were appearing Monday on the website of the American Association for the Advancement of Science (AAAS)."The reality may be more complicated than people think," said Jiang F. Zhong, Ph.D., assistant professor of pathology at the Keck School. "What is a stem cell gene? What is a cancer gene? It may be the same thing.""When you turn off p53, people think the cell becomes cancerous because we tend to focus on the bad thing," Zhong said. "Actually, the cell becomes more plastic and could do good things, too. Let's say the cell is like a person who loses his job (the restriction of p53). He could become a criminal or he could find another job and have a positive effect on society. What pushes him one way or the other, we don't know because the environment is very complicated."Stem cells can divide and differentiate into different types of cells in the body. In humans, embryonic stem cells differentiate into three families, or germ layers, of cells. The reasons why and how certain stem cells differentiate into particular layers are not clearly understood. However, from those layers, tissues and organs develop. The endoderm, for example, leads to formation of the stomach, colon and lungs, while the mesoderm forms blood, bone and heart tissue. In its study, Zhong's team examined human skin cells, which are related to brain and neural cells from the ectoderm.When p53 was suppressed, the skin cells developed into cells that looked exactly like human embryonic stem cells. But, unlike other man-made stem cells that are "pluripotent" and can become any other cells in the body, these cells differentiated only into cells from the same germ layer, ectoderm."IPSCs (induced pluripotent stem cells) can turn into anything, so they are hard to control," Zhong said. "Our cells are staying within the ectoderm lineage."Zhong said he expects that suppressing other oncogenes in other families of cells would have the same effect, which could have critical significance for stem cell therapy. Future research should focus on determining which genes to manipulate, Zhong said.The study is slated to appear in the Proceedings of the National Academy of Sciences later this month, according to AAAS.
BEIJING, Sept. 18 (Xinhua) -- No newly-formed oil belt was detected in the past two days in north China's Bohai Bay from ConocoPhillips' platforms in the Penglai 19-3 oilfield, the State Oceanic Administration (SOA) said.However, new spots of visible oil spills could still be found around platform C, the SOA said in a statement on Sunday.It is estimated that about 4.51 liters of oil leaked into the sea on Saturday, a slight drop from 6.56 liters from Thursday.No oil clean-up work was done on Friday and Saturday due to the strong winds and rough conditions at sea, the statement said.ConocoPhillips China, a subsidiary of U.S. energy giant ConocoPhillips, first reported spills to authorities in June. The oil spills have polluted more than 5,500 square km of sea water in the Bohai Bay since June.The oil spills have spread to beaches in Hebei and Liaoning provinces. The spills have been blamed for losses in the provinces' tourism and aquatic farming industries.The company on Aug. 31 submitted a report to the SOA claiming that it had screened out all potential sources for oil spills and blocked all oil leaks.After days of evaluation, however, the SOA said on Sept. 2 that ConocoPhillips had failed to complete the clean-up.
BEIJING, Sept. 21 (Xinhuanet) -- China will launch an unmanned module next week, paving the way for a planned space station, a spokesman for the space program said on Tuesday.Tiangong-1, or "Heavenly Palace 1", will blast off from Jiuquan Satellite Launch Center in Gansu province between Sept 27 and 30, the spokesman said.The 8.5-ton module, and the Long March II-F rocket that will carry it skyward, were positioned onto the launch pad on Tuesday, signaling that the project has entered the final preparation stage."Scientists will conduct final tests in the next few days before injecting propellants for the launch," Cui Jijun, director of the Jiuquan Satellite Launch Center, said.The program spokesman said that Tiangong-1 will serve as "a target spacecraft" for rendezvous and docking experiments.It will also work as "a platform to test long-term unmanned and short-term manned operations", he said.Technical and medical experiments will provide crucial data ahead of the building of the space station (scheduled for 2020).Three rendezvous and docking experiments will be conducted.An unmanned Shenzhou-VIII craft will be launched later this year to dock with Tiangong-1. In 2012, Shenzhou IX and Shenzhou X will blast off to complete at least one manned docking.Jiao Weixin, a space scientist at Peking University, said that rendezvous and docking - vital maneuvers for manned programs - are hard to master."Rendezvous and docking are difficult because it is like asking two racing cars to keep a distance of 1 meter between them," he said.The mission requires two craft, traveling at speeds of 28,000 km/h, to enter the same orbit and connect with precision, he said.The China Manned Space Engineering Office rescheduled the launch of Tiangong-1 after the failed launch of an experimental orbiter last month.The spokesman said that the carrier rocket to blast off with Tiangong-1 atop has been modified.Only the United States and Russia have mastered rendezvous and docking technology, said Pang Zhihao, deputy editor-in-chief of the magazine Space International.Spacecraft developed by Europe and Japan have utilized US and Russian technology to dock with the International Space Station, he added.
BEIJING, June 3 (Xinhua) -- Google lacked evidence to support its accusations that Chinese hackers are behind the alleged cyber attacks on hundreds of its email accounts and the timing to make such accusations is evil-intentioned, Chinese experts said on Friday."Google's accusation is neither serious nor credible as it has not published any evidence that shows the hackers are from China," said Dai Yiqi, a cyber security expert with Tsinghua University.Eric Grosse, engineering director of Google's Security Team wrote on the company blog Wednesday that unidentified hacker attacks likely originated from the eastern Chinese city of Jinan, tried to collect user passwords of the Gmail accounts of hundreds of users, including senior U.S. government officials, Chinese "human rights activists" and journalists.A report released in 2009 by the United States-China Economic and Security Review Commission, an organization created by the U.S. Congress, claimed that Jinan is the home of a Chinese military reconnaissance office.An anonymous cyber security expert believes, despite Google not referring to the Chinese government in the latest attack claim, the company is targeting the Chinese government by listing the victims of the attacks as those whom only the Chinese government are interested in."Both their intentions and the timing of the accusation are dubious," Dai said.Google's accusation followed on the heel of the reported Pentagon's first formal cyber strategy. The Wall Street Journal reported Tuesday that the Pentagon concluded that computer sabotage coming from another country can count as an act of war and the United States may respond by using traditional military force.Li Shuisheng, a research fellow with a top military science academy of the People's Liberation Army, believes there are political motives behind Google's accusation.Google may well have attempted to instigate a new round of the cyber row between China and the United States, Li said.Wednesday's accusation by Google came more than a year after the company allegedly uncovered a cyber attack on its systems that it said it traced to China.In January, 2010, Google said it had been attacked by hackers supported by the Chinese government, and later announced to withdraw from Chinese mainland. The row ended up with Google redirecting Chinese mainland users to a site in Hong Kong.In such cyber attacks, it is easy to locate the IP address of hackers but hard to tell where the hackers actually are, said Dai."Hackers usually launch attacks by camouflaging their own IP addresses or controlling computers of others. Therefore, we can hardly tell the location of the hacker unless we have sufficient evidence," he said.China is one of the leading targets of cyber attacks. It has the world's largest number of computers infected with bot, a type of malware which allows a cyber attacker to gain control over the affected computer.About 13 percent of the world's computers infected with bot are in China."Without cooperation between governments, absolute security cannot be guaranteed in cyber community," said Li , adding only cooperation can ensure safe information exchange.