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A genetic analysis of COVID-19 patients suggests that blood type might influence whether someone develops severe disease.Scientists who compared the genes of thousands of patients in Europe found that those who had Type A blood were more likely to have severe disease while those with Type O were less likely.Wednesday’s report in the New England Journal of Medicine does not prove a blood type connection, but it does confirm a previous report from China of such a link.“Most of us discounted it because it was a very crude study,” Dr. Parameswar Hari, a blood specialist at the Medical College of Wisconsin, said of the report from China. With the new work, “now I believe it,” he said. “It could be very important.”Other scientists urged caution.The evidence of a role for blood type is “tentative ... it isn’t enough of a signal to be sure,” said Dr. Eric Topol, head of the Scripps Research Translational Institute in San Diego.The study, involving scientists in Italy, Spain, Denmark, Germany and other countries, compared about 2,000 patients with severe COVID-19 to several thousand other people who were healthy or who had only mild or no symptoms. Researchers tied variations in six genes to the likelihood of severe disease, including some that could have a role in how vulnerable people are to the virus. They also tied blood groups to possible risk.Most genetic studies like this are much larger, so it would be important to see if other scientists can look at other groups of patients to see if they find the same links, Topol said.Many researchers have been hunting for clues as to why some people infected with the coronavirus get very ill and others, less so. Being older or male seems to increase risk, and scientists have been looking at genes as another possible “host factor” that influences disease severity.There are four main blood types — A, B, AB and O — and “it’s determined by proteins on the surface of your red blood cells,” said Dr. Mary Horowitz, scientific chief at the Center for International Blood and Marrow Transplant Research.People with Type O are better able to recognize certain proteins as foreign, and that may extend to proteins on virus surfaces, Hari explained.During the SARS outbreak, which was caused by a genetic cousin of the coronavirus causing the current pandemic, “it was noted that people with O blood type were less likely to get severe disease,” he said.Blood type also has been tied to susceptibility to some other infectious diseases, including cholera, recurrent urinary tract infections from E. coli, and a bug called H. pylori that can cause ulcers and stomach cancer, said Dr. David Valle, director of the Institute of Genetic Medicine at Johns Hopkins University.Bottom line: “It’s a provocative study. It’s in my view well worth publishing and getting out there,” but it needs verification in more patients, Valle said.___The Associated Press Health and Science Department receives support from the Howard Hughes Medical Institute’s Department of Science Education. The AP is solely responsible for all content. 3086

A grief-stricken Pittsburgh community will have another day of funerals for victims of a synagogue shooting -- even as it struggles to comfort those affected by the massacre.In yet?another day?of anguish for the close-knit community, mourners will gather Wednesday to bury some of the 11 people killed when a gunman stormed the Tree of Life Synagogue on Saturday.Crowds packed funerals Tuesday, with long lines snaking through streets and busloads of people coming from synagogues nationwide. Pedestrians quietly watched as motorcades and hearses passed by, followed on foot by mourners dressed in black . Others held hands and wept.At least three people have been laid to rest in public funerals this week: Brothers David and Cecil Rosenthal, and Dr. Jerry Rabinowitz. Additional funerals are planned Wednesday and Thursday.Those killed were between ages 54 to 97. 898

A feud between members of the WNBA's Atlanta Dream and one of the team's owner, Sen. Kelly Loeffler (R-Georgia), escalated on Tuesday when Dream players wore shirts supporting Loeffler's opponent in an upcoming special election.Since opening the 2020 season in Bradenton, Florida, the WNBA has taken several steps to honor the Black Lives Matter movement in response to hundreds of nationwide protests against police brutality and systemic racism. Games have taken place on courts emblazoned with the words "Black Lives Matter," and players have worn the names of those who have died at the hands of police on the backs of their jerseys.Loeffler has not been involved with day-to-day team operations since she was appointed to replace Sen. Johnny Isakson, R-Georgia, upon his retirement. But earlier this year, Loeffler said she objected to the league's move to embrace Black Lives Matter, calling it a "divisive political movement." Several WNBA players denounced Loeffler's comments at the time.On Tuesday, members of both the Atlanta Dream and their opponents, the Phoenix Mercury, wore shirts reading "VOTE WARNOCK" during warmups. The shirts refer to Raphael Warnock, a Democrat running in a November special election for Loeffler's seat."We are @wnba players, but like the late, great John Lewis said, we are also ordinary people with extraordinary vision," Dream center Elizabeth Williams wrote on Twitter. "@ReverendWarnock has spent his life fighting for the people and we need him in Washington." 1514

A bomb threat caused the evacuation of parts of Facebook's headquarters in Menlo Park, Calif. on Tuesday, prompting a large police response. The evacuation came around 6 p.m. on Tuesday. Police later gave the all clear.According to KGO-TV, a tip was received by Crime Stoppers in New York, and relayed to authorities in California. The phone call was anonymous and no other details were shared. Many of Facebook's 33,606 employees work out of the company's Menlo Park headquarters. An FBI spokesperson told CNN that a few buildings were evacuated, but all staff members are safe and were allowed to return to the buildings. 661

A former teammate of Colin Kaepernick condemned the NFL's recent embrace of peaceful protest as "half-hearted," calling it "PR for the current business climate."According to former 49ers S Eric Reid, NFL Commissioner Roger Goodell has not personally called to apologize to Kaepernick despite the league's admission that they were "wrong" not to embrace peaceful protest sooner."What the @NFL is doing is half-hearted at best," Reid tweeted Monday. "@nflcommish has gotten comfortable saying he "was wrong" as if his mere acknowledgement reconciles his admitted wrongdoing. He hasn't even called Colin to apologize, let alone reconcile, proving this is only PR for the current business climate."In 2016, Reid was the first player to kneel beside Kaepernick during the national anthem to demonstrate against systemic racism and police brutality.Kaepernick opted out of his contract with the 49ers following the 2016 season. Despite being just 28 at the time and a few years removed from a Super Bowl appearance, Kaepernick has not since been offered a contract by any NFL team.The league has since admitted it was wrong for "not listening to NFL players" regarding anthem protests, but has not mentioned Kaepernick specifically. In the wake of a wave of civil unrest following the death of George Floyd, the Goodell and the NFL released a statement saying that they "encourage all to speak out and peacefully protest." In that same statement, the NFL condemned racism and said it believes that "Black Lives Matter."On Thursday, prior to the 2020 season opener between the Chiefs and Texans, the NFL released a video of Alicia Keys performing "Lift Every Voice and Sing" that featured images of Kaepernick kneeling during the anthem.Reid said Monday that it was "diabolical" that the league used the images of Kaepernick despite the fact that he is still without a job."Roger Goodell uses video of Colin courageously kneeling to legitimize their disingenuous PR while simultaneously perpetuating systemic oppression, that the video he's using fights against, by continuing to rob Colin of his career," Reid said. "It's diabolical."Reid himself has claimed he was blackballed for kneeling alongside Kaepernick. Reid played out his contract with the 49ers and went unsigned in the offseason. During one interview with the Bengals, he claimed team owner Mike Brown specifically asked if he would continue kneeling, and when Reid declined to answer, he was not offered a contract. In 2019, he and Kaepernick settled their collusion grievances against the league for an undisclosed amount.Reid was signed by the Carolina Panthers during the 2018 season. After spending the 2019 season with the team, he was released and is currently a free agent.Dozens of players chose to kneel or raise fists during the national anthem prior to week 1 games on Sunday, including seven teams who chose not to take the field. 2908