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SAN DIEGO (KGTV) — Sunday, San Diego County health officials reported 568 new coronavirus cases and three new community outbreaks, including one at a preschool.The county's new cases were out of 8,943 reported tests, a 6% positive rate, and brought the region's total to 23,682 cases.The three new community outbreaks were reported in a restaurant/bar, in a manufacturing facility, and in a preschool, the county said. In the past week, the county has reported 16 community outbreaks — more than double the trigger of seven community outbreaks in seven days.SAN DIEGO COVID-19 CASE TRACKERThe county has said in the past it will not report where the community outbreaks are located, but says that in the past week there have been outbreaks reported:7/12: 07/13: 37/14: 47/15: 17/16: 27/17: 37/18: 3The three outbreaks reported on July 17 included one in a restaurant/bar, one in a gym, and one in a government setting; and the two on July 17 were both restaurants, according to the county.No new deaths from the virus were reported on Sunday, keeping the county's death toll at 478.Out of the county's cases, 9.3% have needed hospitalization. The county adds that 2.4% of all cases and 25.9% of hospitalized cases had ended up in the ICU.The county continues to fall short on case rate (157.2) and case investigation (7%) triggers. San Diego's case rate trigger is greater than 100 cases per 100,000 people over 14 days, while the trigger for investigations is 70% or less within 24 hours of notification over seven days.See the county's updated triggers dashboard here.San Diego County has remained on the state's monitoring list since July 3. 1652

SAN DIEGO (KGTV) - Super Saturday is set to eclipse Black Friday in sheer numbers, according to the National Retail Federation. The NRF says an "estimated 147.8 million U.S. consumers [are] expected to participate, up from 134.3 million last year, according to the annual survey released today."This includes both in-store and online shopping.This year had the shortest shopping window between Thanksgiving and Christmas, leaving shoppers nervous.Jessica Ramirez said she was so busy working she could only start shopping Saturday. She said the family had been to a few stores that day and she will get as much done as possible in the final countdown before Christmas.Dana Giusti was eating a candy cane while she shopped in Best Buy, saying her sugar fix was staving off anxiety about finishing up Christmas shopping and wrapping all the presents for her family.In Mission Valley, the Target parking lot was filled with lines of cars. Families had different plans of attack to tackle their lists. Some shopped online and picked up curbside, while others braved the crowds inside."NRF defines the holiday season as November 1 through December 31 and has forecast that sales will total between 7.9 and 0.7 billion. Consumers expect to spend an average ,047.83 – including purchases made earlier – for an increase of 4 percent over last year, according to an earlier NRF survey.Today’s survey of 7,779 adult consumers was conducted November 27 through December 5 and has a margin of error of plus or minus 1.2 percentage points." 1543

SAN DIEGO (KGTV) -- The Hillcrest Business Association is making some changes to the Pride kickoff party this year they hope will make the event more inclusive. According to Benjamin Nicholls, the association’s Executive Director, entry to the event won’t be limited to those 21 and up this year. “We just felt it was a little odd to say ‘oh under 21 you can’t come,’ so we took down the fences and made it all ages,” Benjamin said. On top of taking down the fence that normally surrounds the event, entry will also be donation based. “What we want to do is we want to take down the barriers to entry and that means physically taking down the fences and also charging nothing for folks to get in,” Nicholls added. Nicholls says he hopes the changes will get more people involved. Pride this year will be held on July 12, 13 and 14. 840

SAN DIEGO (KGTV) — The California Center for the Arts, Escondido will host drive-in live concerts and a movie series this month.The concerts and movie screenings will be held at the former Nordstrom parking lot at Westfield North County at 8 p.m. Spaces for more than 250 vehicles will be made available and spaced apart to keep listeners distanced.The scheduled shows start on Aug. 14 with a showing of the classic musical Grease and continue on Aug. 15 and 16 with a performance by Jersey Boys stars Christian Hoff and Travis Cloer. Hoff, a Tony Award-winning actor, is best known for his portrayal of the role Tommy Devito from the Four Season’s and Cloer is the longest-running actor to play the role Frankie Valli in Jersey Boys.Tickets to the general public will go on sale on Aug. 1 at 1 p.m. here or by calling 800-988-4253. Tickets start at per car.A portion of ticket proceeds will benefit the Escondido Community Foundation and The Central San Diego Black Chamber of Commerce Foundation.The drive-in series may extend into the fall, the center says. 1072

SAN DIEGO (KGTV) — The Department of Defense has awarded a San Diego biotech company up to million to help develop a next-generation drug to fight COVID-19.Sorrento Therapeutics calls the drug a “rapid countermeasure” against the disease, one that might serve as a vaccine substitute in certain populations or a critical stopgap tool if the virus mutates.“With this, we have a new platform potentially that can respond very quickly to any type of emerging threat,” said CEO Dr. Henry Ji.Sorrento is trying to become the first company to develop an approved DNA-encoded monoclonal antibody treatment. The approach is similar to the experimental monoclonal antibody treatment used on President Trump, but Sorrento’s concept is a more advanced version that offers several benefits.Sorrento’s drug is designed to be used as either a treatment in infected patients or a fast-forming layer of defense in healthy people. The company said its solution should be cheaper and easier to deploy than existing monoclonal antibodies, while offering vaccine-like protective effects that last for several months rather than just two or three weeks.Antibodies are one of the body’s key defense mechanisms. They seek out pathogens and bind to them, marking the invader for destruction like ground troops marking an enemy base for an airstrike. In some cases, antibodies can even neutralize an invader themselves by blocking its method of entry into cells.Monoclonal antibodies are antibodies designed by scientists to neutralize a pathogen. They are hand-picked, genetically modified super antibodies that are cloned in labs.However, the process of growing these super soldiers in the lab is difficult, transporting them requires a cold chain, and as a result, monoclonal antibodies are among the most expensive drugs in the world.Instead of giving people an infusion of pre-made antibodies, Sorrento’s idea is to give people a shot of DNA that instructs some of their cells to churn out perfectly pre-designed antibodies.“It's much easier to make enough DNA to treat a large number of people than it is to make enough protein to treat a large number of people. That’s just a fact about manufacturing,” said Dr. Robert Allen, Sorrento’s chief scientific officer on the project.Dr. Allen said the company is hopeful the drug will induce cells to make protective antibodies for six months or more.This DNA approach to an antibody treatment has never been approved for any disease but other companies are working on their own versions of it. Another biotech with ties to San Diego, Inovio Pharmaceuticals, became the first company to test this approach in humans in 2019 for a drug targeting the Zika virus.Sorrento’s approach is similar to the way DNA vaccines work, but it cuts out intermediary steps and jumpstarts the production of antibodies, rather than leaving the production of antibodies up to the body’s immune system. The result is that protective antibodies can start circulating in days after injection rather than weeks, the company said.“What this is capable of doing is it bypasses the need for the immune system,” said Dr. Mark Brunswick, Sorrento’s senior vice president for regulatory affairs.The drug is unlikely to replace a vaccine in most situations because vaccines can produce other defense mechanisms like T-cells that work in conjunction with antibodies. But the drug might work better than a vaccine for the elderly and others with weakened immune systems who are unable to produce a robust number of antibodies on their own, Brunswick said.Still, the company still has a lot of pre-clinical work and testing to go. Sorrento is hoping to have the drug ready for human trials in four to six months.By then, vaccines from Pfizer and Moderna will likely be widely available, but Dr. Ji said the world needs to prepare for the possibility this virus will mutate.“When you vaccinate hundreds of millions, potentially billions of people, the virus is under tremendous evolution pressure,” he said. “It will escape. It’s guaranteed that the virus is going to mutate and escape all of the vaccines we’re trying to create.”If it does, he said Sorrento will be ready to rapidly deploy its DNA-based countermeasure. 4223