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A Seattle woman rinsed her sinuses with tap water. A year later, she died of a brain-eating amoeba.Her case is reported this week in the International Journal of Infectious Diseases.The 69-year-old, whose name was not given, had a lingering sinus infection. For a month, she tried to get rid of it using a neti pot with tap water instead of using sterile water, as is recommended.Neti pots are used to pour saline into one nostril and out of the other to irrigate the sinuses, usually to fight allergies or infections.According to the doctors who treated the woman, the non-sterile water that she used it thought to have contained Balamuthia mandrillaris, ?an amoeba that over the course of weeks to months can cause a very rare and almost always fatal infection in the brain.Once in her body, the amoeba slowly went about its deadly work.First, she developed a raised, red sore on the bridge of her nose. Doctors thought it was a rash and prescribed an antibiotic ointment, but that provided no relief. Over the course of a year, dermatologists hunted for a diagnosis.Then, the left side of the woman's body started shaking. She'd experienced a seizure that weakened her left arm. A CT scan showed an abnormal lesion in her brain that indicated she might have a tumor, so doctors sent a sample of tissue for testing.Over the next several days, additional scans revealed that whatever was happening in her brain was getting worse. The mass was growing, and new lesions were starting to show up.Finally, a neurosurgeon at Swedish Medical Center, where the woman was being treated, opened her skull to examine her brain and found that it was infected with amoebae.The US Centers for Disease Control and Prevention rushed the anti-amoeba drug miltefosine to Seattle to try to save the woman's life, but she fell into a coma and died.According to the CDC, most cases of Balamuthia mandrillaris aren't diagnosed until immediately before death or after death, so doctors don't have a lot of experience treating the amoeba and know little about how a person becomes infected.The amoeba was discovered in 1986. Since 1993, the CDC says, there have been at least 70 cases in the United States.As in the Seattle woman's case, the infections are "almost uniformly fatal," with a death rate of more than 89%, according to the doctors who treated her and the CDC.The amoeba is similar to Naegleria fowleri, which has been the culprit in several high-profile cases.In 2011, Louisiana health officials warned residents not to use nonsterilized tap water in neti pots after the deaths of two people who were exposed to Naegleria fowleri while flushing their nasal passages. An official urged users to fill the pots only with distilled, sterile or previously boiled water, and to rinse and dry them after each use."Improper nasal irrigation has been reported as a method of infection for the comparably insidious amoeba," the doctors say in the research paper about the Seattle woman. "This precedent led us to suspect the same route of entry for the ... amoeba in our case."The woman's doctors say they weren't able to definitely link the infection to her neti pot, as the water supply to her home was not tested for the amoeba. They hope her case will let other doctors know to consider an amoeba infection if a patient gets a sore or rash on the nose after rinsing their sinuses.Kristen Maki, a spokeswoman for the Washington State Department of Health, said in an email that "Large municipal water supplies ... have robust source water protection programs" and treatment programs, and she noted that "Well protected groundwater supplies are logically expected to be free of any such large amoeba" such as Balamuthia. 3746

A Pinckney, Mich. woman is recovering after she was bitten by a rattlesnake while walking in her yard.Laura Bowen says she was cleaning out her garage, carrying some rakes down a walkway between her home and garage. That's when she says she didn't see the rattlesnake on the ground in front of a garage door, but almost immediately felt a burning pain in her leg when it bit her."It was like a bee sting times 10," Bowen said of the bite. "It was instant fry." Bowen is slowly recovering from the incident, which happened noon on Aug. 20."Just kept telling myself don’t over react because it’s just probably a garden snake or something," she said. "I took a couple shutter steps and looked back and it was a huge snake."The bite happened so fast, and the excruciating pain was almost instant."It was like acid, burn, pain," Bowen said.She says she took a picture of the snake after the bite. Emergency responders immediately recognized it as an Eastern Massasauga Rattlesnake."That was the best thing that I did was to take that photo so they could identify it and know what they were treating," she said.Bowen spent four days in the hospital and received 10 vials of anti-venom. She still plays that day in her head over and over again, and is thankful everything is going to be ok."I think I’m going to buy some garden boots, the rubber ones that are clunky," Bowen said. "Definitely re-thinking my garden attire."She's currently using a cane to help her get around, and should be able to walk on her own again within a week.Bowen has two more doctors appointments just to make sure everything is healing well. 1700

A pet store owner who abandoned her animals, leaving dozens to die in inside a store with no electricity, food or water, faces felony animal cruelty charges.Police arrested Jessica Spangler, 38, of Avon, Illinois is charged with aggravated cruelty to animals after an investigation revealed 41 animals died as a result of her neglect - primarily rodents, birds and reptiles. Another 56 animals - including two cats - survived and have been fostered. The aggravated animal cruelty charge carries a maximum three year prison sentence.Spangler ran Pet Land in Macomb, Illinois as police investigated the store on Saturday, May 26, after receiving complaints of a foul smell. When they entered the store, they discovered numerous dead and poorly cared for animals. Power had been shut off since May 14.During a press conference on Tuesday, May 29, Macomb Police Chief Curt Baker said Spangler said she did not know the animals weren't being cared for and said she had arranged for someone to check on them.Baker also urged people to have patience as the case goes forward, noting Spangler had been the target of many social media threats."Justice will be done," he said. "Please be patient and let the process take place."Spangler had been booked into the McDonough County, where she was released on bond.Police say more charges are likely forthcoming. 1361

A protester was accidentally run over and killed by a car during a demonstration over rising fuel prices, a top official in eastern France said Saturday.Mass demonstrations causing roadblocks across the country are part of the "gilets jaunes" or "yellow vests" movement, which opposes mounting gas prices and eco-taxes on polluting forms of transport.The death occurred when a driver "panicked" and ran over someone after arriving at a blockade for an undeclared protest not far from the city of Lyon, Louis Laugier, the prefect of the Savoie region, said at a news conference.A further 227 people were injured -- six severely -- in protests across the country, and 73 people were taken into police custody, the Interior Ministry said in a statement. Five police officers suffered slight injuries, and one was severely injured. Another five gendarmes were hurt as well.Speaking about the death, French Interior Minister Christophe Castaner said: "That's the reason why we were worried to have people (who are) not experienced organizing protests."Ecology Minister Fran?ois de Rugy called on citizens to "respect caution and safety recommendations" in order for protests to go ahead "without a new tragedy," in a tweet Saturday. He also offered his condolences to the family of the victim.More than 1 million people were expected to turn out Saturday for demonstrations across the country. Partway through the day, the numbers were much lower than that.About 280,000 people participated in more than 2,000 demonstrations, the Interior Ministry said."Honestly we're satisfied, even if it's true we are not hundreds of thousands people here, but still, people have come. The day is not over yet, and we're glad that there are no incidents here," Thierry Paul Valette, who helped organize a protest on the Champs Elysées in Paris, told CNN."We can't stand Macron's taxes any more. It's too much. We couldn't make ourselves heard through political parties or trade unions, so we had to do something."The protest was billed as likely to be one of the toughest tests yet of Emmanuel Macron's 18-month-old presidency.Website blocage17novembre said protests were planned in all 95 of France's mainland departments, while a petition on change.org calling on the French government to lower the cost of fuel has gotten more than 850,000 signatures.In addition to concerns over spiraling fuel prices, the protests also reflect long-running tensions between the metropolitan elite and rural poor. 2490

A new forecast from NOAA now says there is a likelihood of a below-normal Atlantic hurricane season, citing a developing El Nino, lower-than-normal sea surface temperatures, stronger wind shear and drier air.The update is a change from the forecast in late May that called for a normal to slightly above normal season.An average season in the Atlantic sees 12 named storms, six hurricanes, and three major hurricanes. 425