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LOS ANGELES, June 5 (Xinhua) -- U.S. researchers have developed two new drugs that can prolong the lives of patients with advanced melanoma, it was announced on Sunday.Research on both drugs was presented at the on-going annual meeting of the American Society of Clinical Oncology in Chicago, according to HealthDay News.This is the first big news in years for treatment of melanoma, one of the deadliest forms of skin cancer and one that is notoriously difficult to treat, let alone cure, the report said.The first treatment, vemurafenib, inhibits a gene mutation harbored in half of all melanoma patients, but is not yet approved by the U.S. Food and Drug Administration.The other drug, Yervoy (ipilumumab), is an immune system therapy that won approval in March."The March FDA approval of ipilumumab (Yervoy) was the first new drug approval for melanoma in 13 years," said Tim Turnham, executive director of the Melanoma Research Foundation.The two drugs were developed by researchers at Memorial Sloan- Kettering Cancer Center in New York City, the report said."This is really a huge step toward personalized care in melanoma," Dr. Paul Chapman, lead author of the first study and the attending physician in the melanoma/sarcoma service at Memorial Sloan-Kettering, said in a statement. "This (vemurafenib) is the first successful melanoma treatment tailored to patients who carry a specific gene mutation in their tumor, and could eventually become one of only two drugs available that improves overall survival in advanced cancers.""Having two trials that show a benefit in survival in patients with melanoma, both of these in first-line settings -- we weren't here just a few years ago," said Dr. Stephen Hodi, director of the Melanoma Center at Dana Farber Cancer Institute in Boston. "These are huge, paradigm-shifting results for the field."In the vemurafenib trial, sponsored by the drug's makers, researchers randomly assigned 675 patients with advanced, inoperable melanoma to receive either the chemotherapy drug dacarbazine or vemurafenib. Vemurafenib targets the V600E mutation in the BRAF gene.At the three-month mark, patients taking vemurafenib were 63 percent less likely to die and 74 percent less likely to die or see their cancer return, compared to patients taking dacarbazine alone.Few patients had side effects in the vemurafenib group, although some did develop squamous cell carcinoma, a less dangerous form of skin cancer.This is the first drug that has been proven superior to chemotherapy in this group of hard-to-treat patients, the researchers said."There was such a substantial benefit that we recommended that patients cross over," Chapman said at a Sunday news briefing. "It' s unprecedented to report a trial this early. The median follow-up time was three months." Yet the differences between the two groups became evident almost immediately.Dr. Lynn Schuchter, co-moderator of the briefing and division chief of hematology-oncology at Abramson Cancer Center of the University of Pennsylvania in Philadelphia, said symptoms subsided in some patients almost immediately, enabling them to cut back on pain medication in just 72 hours."The median time to progression with dacarbazine was 1.6 months versus three months with vemurafenib, which is a huge difference," said Chapman.In the second study, about 500 patients were randomly picked to receive Yervoy plus dacarbazine or dacarbazine alone.Those taking both drugs lived a median of 11.2 months compared to 9.1 months for those taking dacarbazine alone. Time to recurrence of disease was about the same for both groups: 2.8 months and 2.6 months, respectively.Almost half of those taking the combination therapy were alive after one year, compared to 36.3 percent in the other group. After two years, the rates were 28.5 percent and 17.9 percent, respectively.By three years out, 20.8 percent of those in the combination group were alive compared with 12.2 percent of those taking chemotherapy alone.This is the first study to combine chemotherapy and immunotherapy both safely and effectively.A study to test vemurafenib in combination with Yervoy has already begun, according to HealthDay News.

WASHINGTON, Sept. 13 (Xinhua) -- The U.S. Department of Health and Human Services (HHS), with several partners, on Tuesday launched Million Hearts, an initiative that aims to prevent one million heart attacks and strokes over the next five years.The program will focus on helping Americans make healthy choices, such as preventing tobacco use and lowering consumption of salt and trans fats, and increasing use of treatments like aspirin and blood pressure and cholesterol-lowering medications.The HHS hopes that by 2017, 65 percent of high-risk patients will be taking aspirin and have their blood pressure and cholesterol under control. Currently, only 47 percent of high-risk patients take aspirin, and only 33 percent have their cholesterol and 46 percent their blood pressure under control.They also aim to cut smoking to 17 percent of Americans from 19 percent by 2017, and seek a 20 percent drop in sodium intake and a 50 percent drop in trans fat consumption."Heart disease causes one of every three American deaths and constitutes 17-percent of overall national health spending," said HHS Secretary Kathleen Sebelius in a statement. "By enlisting partners from across the health sector, Million Hearts will create a national focus on combating heart disease."

BEIJING, June 11 (Xinhua) -- The Baidu Charitable Foundation (The Baidu Foundation) and The Bill & Melinda Gates Foundation (The Gates Foundation) founded a strategic charitable alliance here Saturday, in a bid to work for a healthy, smoke-free environment both in China and around the world.Li Yanhong, president of Baidu company, China's top online search engine operator, and Bill Gates, co-chair and trustee of the foundation under the names of the couple, attending the ceremony, both wore a shirt that said, "Say No to Forced Smoking."In his speech at the ceremony, Bill Gates said, "This will be a long-term, open-ended alliance. As a sponsor, Mr. Li and I would like to welcome more partners, and we expect to see more Chinese enterprises and all facets of society to focus on public health issues together."Li Yanhong also addressed the meeting, claiming, "Living healthy and green has become a common pursuit of mankind. We hope the alliance can bring together public efforts for this global cause, so that more people can benefit from our endeavor." ' The alliance's first action is to comply with the government ban on smoking in public places and refuse forced smoking, according to a press release from the foundations.Targeting "forced smokers," the alliance will carry out educational campaign through all channels of media to educate and promote self-awareness about the dangers of forced smoking. Moreover, it will also help existing smokers, especially those who are underage, by sharing scientific methods for quitting.Smoking is one of the world's eight primary causes of death, leading to lung disease, cancer, heart disease, low birth rate, fetal death, tuberculosis, high mortality and many other health issues. Smoking forces many families into poverty by causing both poor health and premature death.China ranks first in tobacco consumption and production in the world. China has 300 million smokers, and one in every three cigarettes smoked in the world is smoked in China. More than half of Chinese smokers are male; and more than 1 million people die from smoking related diseases each year.In addition, China has 740 million "forced smokers," whose health also suffers. The World Health Organization (WHO) notes that there is no safe level of second-hand smoke.This year, China published its 12th Five-Year Plan (2011-2015) that clearly stipulates for "implementing a full-scale ban on smoking in public facilities." This is the first time that tobacco control has been included as part of China's five-year plan for national economic and social development."Rules for Implementation of Public Facilities Health Management Regulations," effective since May 1st, also specifies to "ban smoking at all public indoor facilities," providing legal basis for non-smokers to protect their rights of health and to refuse "involuntary smoking."Aside from tobacco control, the strategic alliance co-founded by the foundations will also collaborate on a series of projects, such as AIDS prevention and control, in a joint effort to promote health for mankind.Founded in 2000, the Gates Foundation currently carries out charity projects in over 100 countries. Since establishing the Beijing Representative Office in 2007, the Gates Foundation has supported a range of health and development projects in China, including the advocacy of smoke-free environment, AIDS and tuberculosis prevention and control, and agricultural development and research projects.Launched in 2010, the Baidu Foundation is committed to use information technology for support of youth and disadvantaged groups, focus on the environment and promote social harmony.Ever since Baidu was founded, Li has actively pushed for tobacco control within the enterprise and the industry. He is the only Chinese member of the United Nation AIDS Prevention Senior Committee and also board member of the HuaXia Charity Foundation.

BEIJING, Sept. 6 (Xinhuanet) -- NASA will launch on Thursday twin lunar orbiters built to map the gravity of Earth's moon in unprecedented detail, media reported Tuesday.The twin lunar probes, Graili-A and Graili-B, will blast off from Florida's Cape Canaveral Air Force Station at 8:37 a.m. EDT and at 9:16 a.m. EDT respectively Thursday, according to NASA.The Grail twins will travel three to four months to get to the moon under a slower but more economical plan.Artist concept of GRAIL mission. Grail will fly twin spacecraft in tandem orbits around the moon for several months to measure its gravity field in unprecedented detail.The two spacecrafts will reach the moon around New Year's Day when they will begin to probe the moon's composition from the crust to the core, according to NASA.The data collected by the probes will be used to better understand the moon's evolution and formation, NASA scientists said.Researchers will also use the twin probes to pinpoint the best landing sites for future explorations.The mission, from start to finish, costs 496 million U.S. dollars. The two Grail probes will crash into the moon after its mission.

SYDNEY, Aug. 16 (Xinhua) -- People sitting in front of TV for hours on end could shorten their life expectancy by almost five years, according to an Australian study published on Tuesday by the British Journal of Sports Medicine.Researchers from the University of Queensland estimate that for every hour adults spend in front of TV, their life expectancy shortens by almost 22 minutes.Those who watched six hours a day lived 4.8 years less than those who don't watch TV.The study is the first in Australia to look into how TV habits affect longevity.The Australian researchers found that watching TV could have a similar negative impact on life expectancy to that of obesity, smoking and low physical activity."People don't realize how it all adds up," the study's lead author Dr. Lennert Veerman told the Australian Associated Press (AAP)."They should try not to watch too much TV and find alternative things to do, preferably things that are light activities," Veerman said.The study was based on data from the Australian Diabetes, Obesity and Lifestyle study and asked more than 11,000 people aged over 25 about their weekly TV viewing time.The study found that in 2008 Australian adults watched 9.8 billion hours of TV."These findings suggest that substantial loss of life may be associated with prolonged TV viewing time among Australian adults," the study said."TV viewing time may have adverse health consequences that rival those of lack of physical activity, obesity and smoking; every single hour of TV viewed may shorten life by as much as 22 minutes," it said."With further corroborative evidence, a public health case could be made that adults also need to limit the time spent watching TV."Australians are recommended to spend at least 30 minutes a day doing moderate-intensity physical activity to reduce an increased risk of developing cardiovascular disease.