永登算命需要多少钱(蛟河哪算命算的好) (今日更新中)

WASHINGTON, Oct. 13 (Xinhua) -- U.S. researchers have corrected sickle cell disease in adult laboratory mice that had been bred to have the inherited blood disorder by activating production of a special blood component, according to a study published online Thursday in the journal Science.Sickle cell disease results from an abnormality in hemoglobin, the protein found in red blood cells that is responsible for transporting oxygen throughout the body. People living with sickle cell disease have two copies of an altered gene that produces sickle hemoglobin instead of normal adult hemoglobin. Sickle hemoglobin changes shape after releasing its oxygen, causing the red blood cell to become stiff, misshapen and sticky, and slowing blood flow to tissues. This process damages organs and causes pain.The study tested a new approach to increasing the production of a third form of hemoglobin -- fetal hemoglobin. Production of fetal hemoglobin predominates before birth, but turns off thereafter as adult hemoglobin production takes over. People with sickle cell disease are unable to make normal adult hemoglobin, and instead make sickle hemoglobin starting in infancy.An elevated level of fetal hemoglobin within the red blood cell reduces the tendency of sickle hemoglobin to change the shape of red blood cells. Considerable research has shown that the drug hydroxyurea increases production of fetal hemoglobin and reduces the number of pain crises and other complications of sickle cell disease in adults and children. However, not all patients respond well to hydroxyurea, and adverse side effects are a concern.The current study explores a more targeted approach to increasing fetal hemoglobin production. It builds upon earlier studies that discovered a protein called BCL11A normally suppresses the production of fetal hemoglobin soon after birth. The researchers viewed the BCL11A protein as a target for therapy and decided to see what would happen if they blocked production of the protein.The paper details how the research team silenced the mouse gene that produces the BCL11A protein in mice with sickle cell disease. Silencing the gene turned off production of the BCL11A protein and allowed the adult mice to continue to produce fetal hemoglobin. It appears to have eliminated disease symptoms without affecting other aspects of blood production."This discovery provides an important new target for future therapies in people with sickle cell disease," said Susan Shurin, acting director of the U.S. National Heart, Lung, and Blood Institute, which co-funded the study. "More work is needed before it will be possible to test such therapies in people, but this study demonstrates that the approach works in principle."Approximately 100,000 Americans live with sickle cell disease. It is most prevalent in people of African, Hispanic, Mediterranean, and Middle Eastern descent. There is no widely available cure for sickle cell disease. Bone marrow transplants have cured some patients, but the treatment is not without risk and most patients do not have relatives who can donate compatible and healthy bone marrow to them.

WASHINGTON, Jan. 1 (Xinhua) -- Twin U.S. spacecraft to study the moon from crust to core put themselves into the lunar orbit on New Year's Eve and New Year's Day, the country's space agency said.The second Gravity Recovery And Interior Laboratory, or GRAIL-B, reached its lunar orbit at 5:43 p.m. EST (2243 GMT) on Sunday, according to the National Aeronautics and Space Administration (NASA).The GRAIL-A started orbiting the moon at 5 p.m. (2200 GMT) Saturday.The insertion maneuvers placed the spacecraft into a near-polar, elliptical orbit with an orbital period of approximately 11.5 hours, NASA said.Over the coming weeks, the GRAIL team will execute a series of burns with each spacecraft to reduce their orbital period to just under two hours. At the start of the science phase in March 2012, the twin GRAILs will be in a near-polar, near-circular orbit with an altitude of about 55 km."NASA greets the new year with a new mission of exploration," Administrator Charles Bolden said in a statement. "The twin GRAIL spacecraft will vastly expand our knowledge of our moon and the evolution of our own planet."During GRAIL's science mission, the two probes will transmit radio signals precisely defining the distance between them. As they fly over areas of greater and lesser gravity caused by visible features such as mountains, craters and masses hidden beneath the lunar surface, the distance between the twin spacecraft will change slightly.Scientists will translate this information into a high-resolution map of the moon's gravitational field.The data will allow scientists to understand what goes on below the lunar surface and increase knowledge of how Earth and its rocky neighbors in the inner solar system developed into the diverse worlds we see today.

BEIJING/CHONGQING, Oct. 16 (Xinhua) -- A team of Chinese and American scientists have discovered the world's only evidence of co-existing human beings and dinosaur tracks in a remote county in southwest China's Chongqing Municipality, according to a paper published Saturday in the Geological Bulletin of China, a Chinese core academic journal.Qijiang County's Lianhua Baozhai, which means "Lotus Mountain Fortress" in Chinese, has a large number of dinosaur tracks as well as a well-preserved fortress and historical epigraph, forming a direct line of evidence that ancient Chinese people built a residence and lived there for a long time, said Xing Lida, one of three researchers with the project as well as a doctoral degree candidate with the Department of Biological Sciences of the University of Alberta in Canada.Chinese people could have lived here for more than 700 years, and the mud cracks, ripple marks and duck-billed dinosaur tracks were considered by them to be lotus leaf veins, water environment and lotus, respectively, which is why they named it the Lotus Mountain Fortress, Xing Lida told Xinhua."Research shows that dinosaur tracks impacted ancient Chinese place names and folklore, so place names and folklore can be major clues for us in tracing dinosaur tracks," Xing said.According to the paper, the Lotus Mountain Fortress dinosaur tracks, the largest track group of cretaceous dinosaurs in southwestern China, contains 350 to 400 footprints that had been preserved in many ways, including concave footprints, convex footprints and multilayered footprints.

BEIJING, Oct. 28 (Xinhuanet) -- Taking aspirin everyday may lower the risk of developing colon cancer for people with the cancer-causing genes, researchers found.The finding was published on Friday in the British medical journal "Lancet".The researchers followed 508 patients with Lynch syndrome, an inherited disorder which increases the risk of developing colon and other cancers.These patients were divided into two groups: members in one group took 600 mg aspirins everyday; another group took only the dummy pills.After 4 years, 10 colon cancer cases were reported among 258 patients who took daily aspirins for at least two years, comparing with 23 cases among 250 patients on dummy pills."This is good news for a very specific population," said Asad Umar, a cancer prevention expert at the U.S. National Cancer Institute.However, the finding doesn't apply to the general public, suggested the lead author of the study John Burn, a geneticist at Newcastle University in England.Only those who are at risk of such diseases should consider taking aspirin regularly, such as people having a family history of colon cancer, he added.

WASHINGTON, Oct. 3 (Xinhua) -- The Rockefeller University confirmed Monday its Canadian-born cell biologist Ralph Steinman died three days before being awarded the Nobel Prize on Monday as the Nobel committee was unaware of his death at the time."Steinman passed away on September 30," the New York university said in a statement."He was diagnosed with pancreatic cancer four years ago, and his life was extended using a dendritic-cell based immunotherapy of his own design."The Nobel committee was unaware of Steinman's death when announcing this year's winners and it was unclear whether the prize would be rescinded because Nobel statutes don't allow posthumous award."The Rockefeller University is delighted that the Nobel Foundation has recognized Ralph Steinman for his seminal discoveries concerning the body's immune responses," says Rockefeller University President Marc Tessier-Lavigne."But the news is bittersweet, as we also learned this morning from Ralph's family that he passed a few days ago after a long battle with cancer. Our thoughts are with Ralph's wife, children and family.""We are all so touched that our father's many years of hard work are being recognized with a Nobel Prize," says Steinman's daughter Alexis. "He devoted his life to his work and his family, and he would be truly honored.""Ralph's research has laid the foundation for numerous discoveries in the critically important field of immunology, and it has led to innovative new approaches in how we treat cancer, infectious diseases and disorders of the immune system," Tessier-Lavigne says.Steinman, who discovered the immune system's sentinel dendritic cells, is this year's recipient of the Nobel Prize in Physiology or Medicine. He shares half the prize with Bruce Beutler and Jules Hoffmann.

来源：资阳报