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Pfizer announced Friday that it would submit a request to the FDA Friday for its COVID-19 vaccine to be granted Emergency Use Authorization.Earlier this week, Pfizer said that a final analysis of trial results showed the vaccine is 95% effective.“Our work to deliver a safe and effective vaccine has never been more urgent, as we continue to see an alarming rise in the number of cases of COVID-19 globally. Filing in the U.S. represents a critical milestone in our journey to deliver a COVID-19 vaccine to the world and we now have a more complete picture of both the efficacy and safety profile of our vaccine, giving us confidence in its potential,” Dr. Albert Bourla, Pfizer Chairman and CEO, said in a press release.Pfizer's two-shot vaccine has already been in mass production for months, and thousands of doses will be ready for delivery if and when the FDA grants authorization. Pfizer says that is on track to produce 50 million doses of the vaccine by the end of 2020 and plans to produce 1.3 billion doses of the vaccine in 2021.According to "Operation Warp Speed," the federal government's plan for distributing the vaccine, upon authorization, the drug will initially be rationed for high-risk populations and health care workers. Dr. Anthony Fauci, the nation's top infectious disease expert, says he believes a vaccine won't be widely available until April.On Wednesday, Pfizer announced that a final analysis of its vaccine candidate showed that of 40,000 participants who participated in the trial, 170 people had contracted the virus. Of those 170 people, 162 received only a placebo injection — meaning just eight out of the 20,000 people who actually received the vaccine contracted the virus.The company added Wednesday that there have been no safety concerns with the vaccine. In a randomized survey of 8,000 participants, only 2% reported suffering severe fatigue, and only 4% reported suffering severe headaches. Those who say they suffered side effects only experienced them briefly after vaccination.Pfizer's announcement comes as COVID-19 cases are spiking around the world. In the U.S. alone, about 2.5 million people have contracted the virus in the month of November alone. Hospitalizations linked to COVID-19 are at an all-time high, and deaths have begun to tick up in recent weeks. 2322

Police say one person was fatally shot in Portland, Oregon, as Black Lives Matter protesters and people from a large caravan of President Donald Trump supporters clashed in the streets. It wasn’t clear if the shooting Saturday night was linked to fights that broke out as a caravan of about 600 vehicles was confronted by protesters in the city’s downtown. Police say the caravan had left the area about 15 minutes before gunshots rang out. Oregon’s largest city has been the site of nightly protests for three months since the police killing of George Floyd in Minneapolis. Trump referenced the city in a speech Thursday at the Republican National Convention. 668

Outside his home, Joshua Nola and his dog, Bud, love spending time together on their daily walks.“No matter what, when I come home, he’s always happy," Nola said. "He’s always in a great mood. He always has a smile on his face."It’s a bond he values deeply. Nola is a U.S. Marine Corps veteran, who deployed to Afghanistan and when he returned home, felt something was off.“I’ve dealt with depression with stuff, dealing with a little bit of survivor’s guilt,” he said. “I have friends that I knew in the Marine Corps, whether on their deployment or after coming home, who just aren’t here anymore. And it got to the point where I was tired of burying brothers.”Those feelings are not unusual for veterans. The VA says more than 1.7 million veterans get treatment for mental health each year.Enter the non-profit Pets For Patriots.“Very simply, Pets For Patriots seeks to give veterans a new pet friend, while saving the most overlooked, undervalued shelter dogs and cats around the country,” said Beth Zimmerman, who founded the nonprofit.Zimmerman said the organization works to help veterans heal emotionally while helping pets in need do the same.“There were two different populations--veterans and shelter animals--that had different, but very complementary needs,” she said. “And if I could find a way to bring them together in a really intelligent way and an innovative way, that it would help both of them.”In the 10 years since Pets For Patriots began, the program has paired together nearly 3,000 veterans with shelter pets around the country. They help not just with the adoption, but also with the pet’s lifelong care.“We inspire veterans to adopt these animals by providing a range of benefits to make pet adoption affordable over the life of that pet,” Zimmerman said.Yet, it amounts to more than that, said Nola.“They’re constantly in contact. They’re asking how I’m doing, how [Bud’s] doing, " Nola said. 'If there’s anything they can do, help with anything, they’ve kind of become like a part of the family.”Zimmerman said that’s part of the goal.“Time and time again, you just see these stories where the veteran heals himself or herself by helping the pet overcome what he or she has been through,” she said. “And it's really pretty amazing.”Back in New Jersey, Nola and Bud continue on their path to healing together.“I wanted to save a dog, just as much as I kind of thought it would save me,” he said.If you would like more information on Pets For Patriots, click here. 2499

PHOENIX — From top restaurants to moving companies, you have probably used Yelp before to find businesses to use. But have you ever thought to use the website to find a daycare?The site can sometimes be a dumping ground for complaints. So, is it credible when looking for someone to look after a child? Researchers at Arizona State University decided to find out.The study included 40 cities and roughly 50,000 submissions on nearly 10,000 childcare facilities. Three of those 40 cities were Phoenix, Mesa and Tucson.Researchers tell KNXV even they were shocked by the findings.They found, through the reviews, that a majority of parents were meticulous and detailed. More than 75 percent gave a 5-star review.As for why they decided research like this was important, ASU said they wanted to see exactly what parents were looking for in childcare, what they were saying in these reviews and how uncovering that could lead to policy changes that could benefit all children.But, despite overwhelmingly positive reviews, lower-income families often reported more bad experiences, disrespect and a lack of learning for their children.Chris Herbst, an associate professor at ASU, was deeply involved in this study. He hopes this research will encourage parents to keep documenting their experiences."It provides this sort of learning loop for childcare providers," Herbst explained. "So, if providers know the parents... feel a certain way about the program, then providers can use this information to inform their... quality improvement activities."While these reviews are a good start, Herbst stresses that parents have plenty of tools they can use, beyond just basing it on online reviews.One suggestion he gives is using the Quality Rating and Improvement System.Parents can search their state and look-up different facilities to see how this system evaluates and rates the program's quality.KNXV also reached out to Erin Raden for more tools and advice for parents. She is the executive director of the Arizona Early Childhood Education Association.In regards to using online reviews like Yelp, Raden said it is good to use. However, it should not be the only way you make a childcare decision."You may have a parent that's upset about something," Raden said. "And that might be the right choice for them to no longer take their child there. But that doesn't mean that it wouldn't be the right choice for you."Raden also suggests taking your time and visiting at least two or three facilities."It's just going to be a lot about what feels right to you and you should always trust your instincts," Raden explained.She said that it is not about a facility being the most beautiful place, but instead look at how the students are engaged with their instructors. 2826

PINE VALLEY, Calif. (KGTV) - A Pine Valley restaurant owner is defying San Diego County orders to move his restaurant outside, saying he will continue to ignore the purple tier rules to keep his business afloat.When it was announced that San Diego County would move into the more restrictive purple tier, Major’s Diner owner Larry McNamer told ABC 10News he had plans to stay open inside, even though all restaurants are required to move outside completely. He stayed true to his word, operating indoors, saying he still follows social distancing practices, but needs the inside space because his restaurant is only open for breakfast and lunch, and the winter months bring temperatures in the 30s for the mountain community.“They’re saying they wanted us back outside and we said no absolutely not, not going to do it,” said McNamer.RELATED: "We are over it." Pine Valley restaurant plans to defy county orderHe said after his plans to stay open inside were shared with the community, people made a point to order from him the first weekend in support.“We had people coming in from the North County saying they were coming in just to support us for staying open. It was really nice to see that there was a lot of people that care about the businesses and want us to stay open and are willing to fight alongside us for this thing,” McNamer said.He added that in the first two days of openly defying the tier, the only interaction he’s had with the County or officials has been one call from his health inspector.“He was just wondering what our intentions really were. His boss had asked him to call me and ask where we’re standing on this,” said McNamer.McNamer said he has no plans to close his indoor operations, even if he receives warnings. He said if the County decides to fine him, they won’t be receiving any money from him.“Great, bring it on. I can barely pay my bills now, where do you think that money is going to come from. You won’t get it,” he said.He is not alone. Other business owners in San Diego have similar frustrations. A reopen rally is set for Monday afternoon at the County Administration Building. A flyer for the event says the plan is to meet at Time Out Sports Tavern at 2:30 then walk to the Administration Building, with a rally there planned for 3:30 p.m.RELATED: San Diego County politicians vie to reopen businesses in purple tier 2372