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BEIJING, August 1 (Xinhuanet) -- U.S. researchers have discovered a genetic mutation unique to African Americans that links to heighten their asthma risk, according to reports published on Sunday in the journal Nature Genetics.Researchers of University of Chicago found a gene, PYHIN1, and its variations may account for asthma risk in people of African descent. In their study, they examined data from nine previous genome-wide association studies, totaling more than 2 million single nucleotide polymorphisms in 3,246 asthma patients and 3,385 control patient, 1,702 patient-parent groupings, 355 family-based cases, and 468 family-based controls.In the study, the researchers found that between 26 percent and 29 percent of people of African-descent carried at least one copy of the gene. In particular, one polymorphism of the gene was 34 percent more likely found in African-American and Afro-Caribbean people with asthma. More interestingly, this variant of the gene is rarely found in Caucasian people and in Latino population, it was found in less than 5 percent.This new variant is part of a family of genes linked with the body's response to viral infections. It is thought to be involved in interferon signaling, which could influence the occurrence of asthma.The team stressed that each gene variant on its own plays only a small role in increasing asthma risk, but that risk could be multiplied when combined with other risk genes and with environmental factors.
PARIS, June 14 (Xinhua) -- Solar Impulse, a Swiss solar-powered aircraft, finally arrived in Paris on Tuesday after three days' delay, ready for a debut at the biennial International Paris Air Show.The 1.6-ton solar-powered plane was expected to land in Paris on Saturday but technical problems and bad weather forced it to turn back to Brussels.The plane took its first international flight from Switzerland to Brussels on May 13 and then marked its second international flight to Paris. It has 12,000 solar cells mounted on the wings, which provide momentum for its four electric motors.Solar Impulse is the first aeroplane designed to fly day and night without requiring fuel and without producing carbon emission. The 64-meter-wingspan (as wide as an Airbus A340) can fly at extremely slow speed and has a weight equivalent to that of an average family car.Regarded as a "special guest" in the show, Solar Impulse made a historic 26-hour day and night flight without fuel in July 2010.During the Paris air show from 20 to 26 June, visitors can enjoy a close look at the innovative plane on ground every day and if weather condition permits, flying displays will take place.According to Paris Air Show organizers, 59 of the top 100 companies in the air industry worldwide will be present. More than 1,800 small and medium-sized companies will be exhibiting their products during the one-week show. Enditem
WASHINGTON, June 16 (Xinhua) -- Cells in the human body are constantly being exposed to stress from environmental chemicals or errors in routine cellular processes. While stress can cause damage, it can also provide the stimulus for undoing the damage. New research by a team of scientists at the University of Rochester has unveiled an important new mechanism that allows cells to recognize when they are under stress and prime the DNA repair machinery to respond to the threat of damage.Their findings will be published Friday in journal Science. Cells in the human body are constantly being exposed to stress from environmental chemicals or errors in routine cellular processes. While stress can cause damage, it can also provide the stimulus for undoing the damage.The scientists, led by biologists Vera Gorbunova and Andrei Seluanov, focused on the most dangerous type of DNA damage -- double strand breaks. Unrepaired, this type of damage can lead to premature aging and cancer. They studied how oxidative stress affects efficiency of DNA repair. Oxidative stress occurs when the body is unable to neutralize the highly-reactive molecules, which are typically produced during routine cellular activities.The research team found that human cells undergoing oxidative stress synthesized more of a protein called SIRT6. By increasing SIRT6 levels, cells were able to stimulate their ability to repair double strand breaks. When the cells were treated with a drug that inactivated SIRT6, DNA repair came to a halt, thus confirming the role of SIRT6 in DNA repair. Gorbunova notes that the SIRT6 protein is structurally related to another protein, SIR2, which has been shown to extend lifespan in multiple model organisms."SIRT6 also affects DNA repair when there is no oxidative stress," explains Gorbunova. "It's just that the effect is magnified when the cells are challenged with even small amounts of oxidative stress."SIRT6 allows the cells to be economical with their resources, priming the repair enzymes only when there is damage that needs to be repaired. Thus SIRT6 may be a master regulator that coordinates stress and DNA repair activities, according to Gorbunova.
BEIJING, July 5 (Xinhuanet) -- Facebook CEO Mark Zuckerberg confirmed that he has signed up to Google+, the new social networking platform from Google, according to media reports Tuesday.Launched last month, Google+ is the Internet giant's latest foray into social networking.Zuckerberg confirmed that the profile with his name on Google+ belongs to him only, and said, "Why are people so surprised that I'd have a Google account?" Facebook CEO Mark Zuckerberg reacts after unveiling a new messaging system during a news conference in San Francisco, California November 15, 2010.In social networking field, it is rare for someone to join the rival's platform, therefore, Zuckerberg's move is considered strange.But interestingly, Zuckerberg has more followers than Google founders Larry Page and Sergey Brin, and even Vic Gundotra, the man behind Google+, with over 21,000 people.Besides Google+, Zuckerberg also has an account on Twitter, though it has not been updated for some time.
BEIJING, Sept. 1 (Xinhua) -- Chinese scientists have decided to reschedule the launch of the Tiangong-1, an unmanned space module, due to the failed launch of an experimental orbiter, a spokesperson with the project said Thursday.The decision to delay the launch was based on the consideration that the carrier rocket Long-March II-F, which would be used for the upcoming launch, belongs to the same series as the malfunctioning one that led to the experimental orbiter SJ-11-04 failing to enter Earth's orbit in August."As the investigation into the malfunction of the rocket Long-March II-C remains underway, it is not clear yet whether the malfunction is linked with the Long-March II-F," the unnamed spokesperson said.Previously, the Long-March II-F was expected to send the 8.5-metric ton Tiangong-1, or "Heavenly Palace 1," into space in the second half of this year to perform the nation's first space-docking procedure.The Tiangong-1 will dock with the unmanned Shenzhou-8 spacecraft, which will be sent into space after the Tiangong-1's launch."The specific launch date for the Tiangong-1 will be set based on the results of the investigation into the malfunctioning rocket," the spokesperson said, adding that the project's teams are currently double-checking every product that will be involved in the space-docking.The Shenzhou-8 spacecraft, the Long March II-F carrier rocket, and the Tiangong-1 have all been transferred to the Jiuquan Satellite Launch Center in northwest China's Gansu Province, the spokesperson said.