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2025-05-23 22:13:37
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  本溪哪里有算命的地方   

NEW YORK (AP) — The operator of Ann Taylor and Lane Bryant filed for Chapter 11 bankruptcy on Thursday, the latest retailer to do so during the pandemic. Ascena Retail Group, which operates nearly 3,000 stores mostly at malls, has been dragged down by debt and weak sales for years. In a press release, the company said they were closing all of their plus-size stores Catherines.The company also said in the release that they plan to "strategically reduce its footprint with the closing of a significant number of Justice stores and a select number of Ann Taylor, LOFT, Lane Bryant, and Lou & Grey stores."It joins other retailers that have filed for bankruptcy in recent weeks, including Brooks Brothers, Neiman Marcus, J.C. Penney, and J. Crew. These retailers were already struggling with poor sales, but the forced closure of stores in March to reduce the spread of the coronavirus put them further in peril. Experts believe that there will be another wave of bankruptcies this fall that will include companies that had been healthy before the pandemic struck. 1076

  本溪哪里有算命的地方   

North Korean leader Kim Jong Un responded to President Donald Trump's speech before the United Nations where Trump vowed to "totally destroy" the nation if it threatened the United States or its allies. Although the two nations are not formally at war, clearly the two leaders are in a war of words. "The United States has great strength and patience, but if it is forced to defend itself or its allies, we will have no choice but to totally destroy North Korea. Rocket Man is on a suicide mission for himself and for his regime," Trump said earlier this week. Kim issued a statement Thursday evening, not backing down to Trump's hard-line stance."I will make the man holding the prerogative of the supreme command in the US pay dearly for his speech calling for totally destroying the DPRK," Kim said. "Whatever Trump might have expected, he will face results beyond expected." "He is unfit to hold the prerogative of supreme command of a country and he is surely a rogue and a gangster fond of playing with fire rather than a politician," Kim added.Both sides have stepped up their posture toward one another. North Korea has fired missiles over the coast of Japan, and has tested atomic weapons. Meanwhile, the United States has added patrols of the region.  1299

  本溪哪里有算命的地方   

NEWWARK, N.J. – OxyContin maker Purdue Pharma has pleaded guilty to three criminal charges and formally admitted its role in the opioid crisis.Tuesday's plea before a judge in Newark, New Jersey, is part of a larger settlement with the U.S. Department of Justice that also includes resolving civil claims.The Stamford, Connecticut-based company is to pay 5 million as part of the deal, while billion in forfeitures and penalties could be waived because of a proposed deal to resolve thousands of other lawsuits.Advocates are upset that the guilty plea applies only to the company and not executives or members of the Sackler family who own it.During Tuesday’s hearing, Purdue Pharma admitted to impeding the US. Drug Enforcement’s efforts to combat the addiction crisis and acknowledged it paid doctors to induce them to write more prescriptions for its painkillers.More than 750,000 people have died from drug overdoses since 1999, according to the Centers for Disease Control and Prevention (CDC).The CDC says two out of three overdose deaths in 2018 involved opioid, which are substances that work in the nervous system of the body or in specific receptors in the brain to reduce the intensity of pain.Since 1999, the CDC says overdose deaths involving opioid like prescription drugs and heroin have increased six times. 1337

  

NEW YORK (AP) — Andy Ruiz Jr. had six weeks to prepare for the fight of his life.He'll have a lifetime to celebrate one of boxing's biggest heavyweight stunners.A massive underdog just like Buster Douglas, Ruiz knocked down British champion Anthony Joshua four times, and the final two in the seventh round proved the decisive blows.Ruiz, the first heavyweight of Mexican descent to win a heavyweight title, capped one of boxing's epic upsets to win Joshua's shares of the heavyweight championship Saturday night at Madison Square Garden."I just feel so good, man," Ruiz said. "This is what I've been dreaming about, this is what I've been working hard for. I can't believe I just made my dreams come true."Ruiz etched his name in heavyweight lore by TKO at 1:27 in the seventh round to become the surprise champ in a bout that had shades of Douglas' upset over Mike Tyson for the heavyweight title in 1990. Ruiz barely was on anyone's heavyweight radar when he was summoned as a replacement to fight the undefeated Joshua in front of a packed Garden.Considered a joke by fans, all Ruiz did was dominate the British champion and used a TKO to turn his life and the heavyweight division upside down. Ruiz racked up 32 wins without beating many boxers of note and walked into the ring with a waistline that will need a supersized championship belt.Ruiz, a flabby fighter out of Southern California, came up short in his only other shot at a world title, having lost on points to then-WBO champion Joseph Parker in December 2016.Ruiz even warned Joshua before the fight: "Don't underestimate this little fat boy."The 270-pound heavyset heavyweight knocked down Joshua twice in the third round and did it two more times in the seventh before referee Mike Griffin ended the fight. Joshua was woozy and seemed to stumble toward the wrong corner after the final blow.Ruiz stepped in after fighting on April 20, when he stopped Alexander Dimitrenko. Jarrell Miller's failed drug tests sent the challenger to the sideline and paved the way for Ruiz's unexpected title shot. Ruiz (33-1, 21 KO's) seized the opportunity and made boxing history to win the WBA/IBF/WBO/IBO championships. He raised his arms in celebration and jumped around the ring as his corner quickly mobbed him and a wild celebration kicked off."I've got that Mexican blood in me," he said. "Talking about the Mexican style? I just proved it."The true shock might have been that the Garden was packed on a Saturday night for a fight few expected to be competitive. Yes, Ruiz is up there with Douglas and Hasim Rahman for who-can-believe-it wins, but casual sports fans don't even know the names of most boxing champions — consider, instead of pay-per-view parties, this card was streamed by DAZN.When ring announcer Michael Buffer announced the name of the judges "should this fight go the distance," fans laughed at the ridiculous possibility as Ruiz was an ultimate underdog.Joshua (22-1, 22 KO's) and Ruiz were both knocked down in an electrifying third round that had the sellout crowd of 20,201 howling with each heavy hit. Joshua knocked down Ruiz early in the round and the promise of an early finish seemed horizon.Ruiz, his trunks a bit too low for his portly frame, came right back and used an overhand right that rocked the champ and sent him to the canvas. Joshua recovered only to get pummeled in the corner. Ruiz knocked him down again in the final ticks of the round as fans in a disbelieving Garden crowd screamed "Oh my God!" Again, Joshua beat the count but the bell saved the Brit from a going a second longer in his weakened state. Had it not been a championship fight, perhaps Griffin would have stopped the bout.Alas, for Joshua, it went on.Ruiz, whose father, a native of Mexico, got him into the gym when he was 6 and had his son in bouts a year later, shook up the boxing world. Johsua was the fan favorite and had all the hype for his first fight in the United States."If it wasn't for my dad, I wouldn't be here," Ruiz said.NBA star Kyrie Irving and rapper Meek Mill were among the celebrities in the house expecting Joshua to roll to a win and set up more ambitious, lucrative bouts against the likes of Tyson Fury, Deontay Wilder and a few other potential opponents."Sorry I let my fans down, sorry I let my supporters down," Joshua said.Ruiz made some new ones."It is never over until it's over with the Mexicans. God bless them. Congrats Andy Ruiz," former UFC champion Conor McGregor tweeted.Wilder, owner of the WBC crown, decided to give Luis Ortiz a rematch. Ortiz battered Wilder for parts of their fight in early 2018 before running out of gas and getting knocked out.Wilder tried to steal the headlines this week when he announced his rematch with Fury was set for 2020. Wilder and Fury fought to a split draw in December in Los Angeles, with Wilder retaining his WBC heavyweight title after knocking down his British challenger twice.Joshua instead heads toward a likely rematch against Ruiz later this year.Fans booed when Ruiz was shown on the big screen holding a personalized Knicks jersey. He walked out to his press conference wearing the jersey — his coronation complete, a table full of championship belts all for him."My life is going to change," he said. "I don't have to show them no more." 5306

  

New research suggests that antibodies the immune system makes to fight the new coronavirus may only last a few months in people with mild illness, but that doesn’t mean protection also is gone or that it won’t be possible to develop an effective vaccine.“Infection with this coronavirus does not necessarily generate lifetime immunity,” but antibodies are only part of the story, said Dr. Buddy Creech, an infectious disease specialist at Vanderbilt University. He had no role in the work, published Tuesday in the New England Journal of Medicine.The immune system remembers how to make fresh antibodies if needed and other parts of it also can mount an attack, he said.Antibodies are proteins that white blood cells called B cells make to bind to the virus and help eliminate it. The earliest ones are fairly crude but as infection goes on, the immune system becomes trained to focus its attack and to make more precise antibodies.Dr. Otto Yang and others at the University of California, Los Angeles, measured these more precise antibodies in 30 patients diagnosed with COVID-19 and four housemates presumed to have the disease. Their average age was 43 and most had mild symptoms.Researchers found that the antibodies had a half-life of 73 days, which means that half of them would be gone after that much time. It dovetails with a previous report from China also suggesting antibodies quickly fade.The results “call for caution regarding antibody-based ‘immunity passports,’ herd immunity, and perhaps vaccine durability,” the California authors write.That’s true, Creech said, but other parts of the immune system also help confer protection. Besides churning out antibodies, B cells develop a memory so they know how to do that again if needed.“They would get called into action very quickly when there’s a new exposure to the virus. It’s as if they lie dormant, just waiting,” he said.Other white blood cells called T cells also are better able to attack the virus the next time they see it, Creech said.Although circulating antibodies may not last long, what we need to know is if and how people remake antibodies if exposed to the coronavirus again and if they protect against another infection, Alison Criss, an immunologist at the University of Virginia, wrote in an email. “We also need to know if there is a protective T cell response” that reappears.Vaccines, which provoke the immune system to make antibodies, might give longer-lasting protection than natural infection because they use purified versions of what stimulates that response, she noted.Creech agreed.“This shouldn’t dissuade us from pursuing a vaccine,” he said. “Antibodies are only a part of the story.”___Marilynn Marchione can be followed on Twitter at http://twitter.com/MMarchioneAP___The Associated Press Health and Science Department receives support from the Howard Hughes Medical Institute’s Department of Science Education. The AP is solely responsible for all content. 2967

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