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Maryland-based vaccine developer, Novavax, has received .6 billion from the federal government to complete late-stage clinical development; set up large-scale manufacturing; and deliver 100 million doses of NVX?CoV2373, its COVID-19 vaccine candidate, as early as late 2020.This is the largest vaccine deal to date with the Trump administration as part of their Operation Warp Speed, which is focused on making a COVID-19 vaccine and treatments available as quickly as possible.Novavax has not brought any of their developed vaccines to market. According to information on their website, they have developed several vaccines for infectious diseases, however they are all in various stages of development or clinical trials. These include vaccines for the seasonal flu and RSV. Other vaccines created by Novavax are not actively being developed or studied at this time, including ones for Ebola, MERS, and SARS.According to a statement from Novavax, the agreement with the federal government includes the company demonstrating being able to rapidly get manufacturing and large-scale production of the vaccine going once approved. Novavax hopes to conduct their late-stage clinical study with 30,000 subjects in fall 2020.An early-stage clinical study took place in Australia in May on 130 participants. Study results are expected at the end of July.“Today’s .6 billion investment supports the Novavax candidate, depending on success in clinical trials, all the way through to manufacturing 100 million doses for the American people,” said U.S. Health and Human Services Secretary Alex Azar.Regeneron Pharmaceuticals has also received 0 million through Operation Warp Speed on Tuesday, to make and supply its COVID-19 vaccine candidate, REGN-COV2. Their vaccine is currently in phase 2 and phase 3 clinical studies for the treatment and prevention of COVID-19.Regeneron has several vaccines on the market currently, including Dupixent, used to treat allergic diseases such as eczema, asthma and nasal polyps which result in chronic sinusitis, and Praluent, used to treat high cholesterol. 2101

Many districts across the country are looking ahead to this fall and trying to make plans about how students could, or should, return to the classroom. A nationwide pediatric group is urging local leaders, parents and education systems to collaborate and create policies that allow for as much in-person learning this fall as possible.The American Academy of Pediatrics released guidance on their website based on in-person attendance at schools being not only fundamental to children’s mental, social and physical development, but also playing “a critical role in addressing racial and social inequality … it is critical to reflect on the differential impact SARS-CoV-2 and the associated school closures have had on different races, ethnic and vulnerable populations.”The recommendations include masks, physical distancing, and outdoor play, with more specifics. Such as, the AAP recommends placing desks 3-to-6 feet apart as long as it allows children to attend school; the 3-foot distance can be used when face coverings are also being worn.Middle and high schools should avoid groupings of students inside doing activities involving exhalation, i.e. singing, exercising, etc. according to the recommendations. The AAP also encourages limiting locker use and moving from room-to-room for classes.The guidance extends to school faculty and staff, with the AAP urging districts to make sure adults in schools get the support they need to set a good example and stay healthy.“In the same way that students are going to need support to effectively return to school and to be prepared to be ready to process the information they are being taught, teachers cannot be expected to be successful at teaching children without having their mental health needs supported.The U.S. Centers for Disease Control and Prevention last updated their guidance to schools and care facilities in April and it is focused on quickly stopping an outbreak, cleaning facilities and maintaining continuity in education and meal accessibility.AAP acknowledges any school policy this fall should be flexible and nimble, able to respond to new information about the coronavirus and specific needs in each school, district and region.“Although schools should be prepared to be agile to meet evolving needs and respond to increasing knowledge related to the pandemic and may need to institute partial or complete closures when the public health need requires, they should recognize that staff, students, and families will benefit from sufficient time to understand and adjust to changes in routine and practices.” 2591

McDonald's is celebrating International Women's Day with a big, gleaming, W."For the first time in our brand history, we flipped our iconic arches," said McDonald's Chief Diversity Officer Wendy Lewis.The giant arches have been physically flipped at just one California restaurant. On Thursday, International Women's Day, upside-down arches will replace rightside-up arches across McDonald's digital channels.Lewis said McDonald's is flipping its logo "in honor of the extraordinary accomplishments of women everywhere."The restaurant chain will also mark the occasion at another 100 US locations, where McDonald's employees will wear special hats and shirts.Related: McDonald's is taking cheeseburgers out of the Happy MealIn recent years, companies have started using International Women's Day to broadcast their views on gender equality."International Women's day is a perfect opportunity for brands to talk about their commitment to empowerment," said Tim Calkins, a marketing professor at Northwestern University's Kellogg School of Management."It's a perfect venue to get out there and enhance your brand perception," he said.In a statement, McDonald's said that 6 out of 10 managers of US restaurants are women."We have a long history of supporting women in the workplace," the company added.Related: McDonald's is going greenBrands may also be eager to replicate the success of others, Calkins said."When companies see high-profile campaigns that get some traction and get some discussion, they are very quick to jump on the bandwagon."One example of a particularly successful campaign is the "Fearless Girl," sculpture, which was installed across the "Charging Bull," in New York City by State Street ahead of International Women's Day last year.The statue was designed by the financial services company and the advertising firm McCann to call attention to State Street's efforts to improve gender diversity on corporate boards. But it soon took on a life of its own.The-CNN-Wire? & ? 2018 Cable News Network, Inc., a Time Warner Company. All rights reserved. 2080

Martin Shkreli was sentenced to seven years in prison on Friday for defrauding investors out of more than million.Shkreli, who gained notoriety for inflating the price of a life-saving drug, had faced up to 20 years behind bars for mismanaging money at three hedge funds.He was convicted on August 5, 2017 of securities fraud and conspiracy in what prosecutors said amounted to a Ponzi scheme. Shkreli called the charges "a witch hunt of epic proportions."The-CNN-Wire? & ? 2018 Cable News Network, Inc., a Time Warner Company. All rights reserved. 564

Mental health experts are concerned that people who are unemployed amid the COVID-19 pandemic may be experiencing more mental health issues.Art Goldsmith, a professor of economics at Washinton and Lee University, says that some people who don't have a financial buffer — particularly minorities or people who have young kids — might become more emotionally distressed by losing their job.Unemployed people are normally optimistic at first. But after five or six weeks, feelings of hopelessness or anxiety increase."That's when I would say the psychological distress really arise, and poor emotional well-being starts to become a footprint of that bout of unemployment," Goldsmith siad.According to Maria Heidkamp, the director of the New Start Career Network at Rutgers University, that's concerning because the number of people who have been unemployed long-term has ballooned during the pandemic. She says that combing the stress of the health emergency with the pressure of being unemployed compounds an already difficult process."Your self-esteem can take a beating if you apply for jobs and get a series of rejections, and you don't know why. Or maybe you don't hear anything." Heidkamp said. "Even pre-pandemic, we know how stressful it is. "Heidkamp says that unemployed people should break up their job search and related goals into small, manageable steps. She suggests re-doing resumes or building an online presence in small chunks.She also suggests finding activities that reduce stress during unemployment and searching for part-time work while continuing to look for full-time employment.New Start Career Network is also partnering with the Mental Health Association of New Jersey to offer online health and wellness workshops. 1749

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