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WASHINGTON, June 16 (Xinhua) -- Cells in the human body are constantly being exposed to stress from environmental chemicals or errors in routine cellular processes. While stress can cause damage, it can also provide the stimulus for undoing the damage. New research by a team of scientists at the University of Rochester has unveiled an important new mechanism that allows cells to recognize when they are under stress and prime the DNA repair machinery to respond to the threat of damage.Their findings will be published Friday in journal Science. Cells in the human body are constantly being exposed to stress from environmental chemicals or errors in routine cellular processes. While stress can cause damage, it can also provide the stimulus for undoing the damage.The scientists, led by biologists Vera Gorbunova and Andrei Seluanov, focused on the most dangerous type of DNA damage -- double strand breaks. Unrepaired, this type of damage can lead to premature aging and cancer. They studied how oxidative stress affects efficiency of DNA repair. Oxidative stress occurs when the body is unable to neutralize the highly-reactive molecules, which are typically produced during routine cellular activities.The research team found that human cells undergoing oxidative stress synthesized more of a protein called SIRT6. By increasing SIRT6 levels, cells were able to stimulate their ability to repair double strand breaks. When the cells were treated with a drug that inactivated SIRT6, DNA repair came to a halt, thus confirming the role of SIRT6 in DNA repair. Gorbunova notes that the SIRT6 protein is structurally related to another protein, SIR2, which has been shown to extend lifespan in multiple model organisms."SIRT6 also affects DNA repair when there is no oxidative stress," explains Gorbunova. "It's just that the effect is magnified when the cells are challenged with even small amounts of oxidative stress."SIRT6 allows the cells to be economical with their resources, priming the repair enzymes only when there is damage that needs to be repaired. Thus SIRT6 may be a master regulator that coordinates stress and DNA repair activities, according to Gorbunova.
BEIJING, June 26 (Xinhua) -- China on Sunday issued a regulation on drug rehabilitation that encourages drug users to voluntarily undergo rehabilitation programs.The regulation took effect Sunday as a supplement of the country's anti-drug law that was implemented three years ago.Drug users who voluntarily receive intervention programs "will be exempt from punishment," said the regulation, promulgated on the 24th International Day Against Drug Abuse and Illicit Trafficking, which falls on Sunday.With seven chapters and 46 articles, it also stipulates the rights and obligations of drug addicts, as well as supporting measures for voluntary, community-based, and government-ordered drug rehabilitation.Up to date, more than two million Chinese have been receiving compulsive rehabilitation or treatment, statistics show. However, many of them find it difficult to completely give up the addiction.The regulation, aiming to explore effective ways to curb drug use, calls for boosting "the role of communities and families" in helping reduce drug users' dependency on narcotics.It asks rehabilitation centers to provide addicts with consulting services and education on the prevention of HIV/AIDS and other contagious diseases.Efforts should be made to "boost pharmaceutical management" so as to prevent loss or abuse of psychotropic substances and narcotics, the regulation says.The regulation also stipulates on the protection of drug addicts' personal information, saying "members of the police, judiciary and health departments who cause the leak of personal information must be punished."The regulation has solicited public comments before it was released.Transnational drug trafficking remains rampant in China, particularly in southwestern border regions of Yunnan and Guangxi.A report issued last month by China's National Narcotics Control Commission said authorities investigated 89,000 drug-related crimes and arrested 101,000 suspects last year.Law enforcers confiscated 5.3 metric tonnes of heroin and one metric tonne of opium in 2010, the report said, adding that intervention programs were used to treat and rehabilitate some 175,000 drug addicts last year.

RAMALLAH, Aug. 26 (Xinhua) -- China's special envoy to the Middle East, Wu Sike, said here Friday that his country fully supports the Palestinians' right to establish an independent state in a balanced manner and through peace talks."China supports the Palestinian people and their cause. We also support the Palestinians to get the United Nations recognition of a Palestinian state on the lands occupied in 1967 with Jerusalem as capital," he told Xinhua in Ramallah.The envoy said peace talks with Israel are the best way to reach a settlement, adding that gaining UN recognition is not an alternative to peace negotiations.China supports a two-state solution -- Israel and an independent Palestinian state living side-by-side in peace and security, he said, noting that he believes the current developments in the Middle East have a positive impact on the Palestinian cause."The Middle East witnesses many changes. People have many chances to participate in political life. The Palestinian cause is a main issue that attracts the attention of the Arab people," he said."The recent meeting of the Arab League Peace Initiative Follow- Up Committee in Qatar assures the Arabs' support to the Palestinians' bid for full UN membership," he said. "This will help the Palestinians gain more international support."The Palestinians say they will approach the UN in September to get full membership of the world body as peace talks with Israel have long been deadlocked, a move disapproved by Israel and the United States.Wu expressed his appreciation of the reconciliation deal signed between Palestinian National Authority President Mahmoud Abbas' Fatah party and Hamas movements in Cairo in May."This move will help the Palestinians to have more countries on their side," he said.Wu said his Middle East tour was taking place at an important moment as the region is witnessing crucial changes, stressing that China respects the choices of the peoples."The Arab peoples are able to make their own decisions toward development," said the envoy.He also said the ties between China and the Arab countries are based on strong foundations, regardless of the changes taking place in the region.Wu met with Palestinian President Mahmoud Abbas and other officials Tuesday, the first day of his ongoing Middle East tour.This was Wu's second visit to Palestinian territories this year, after which he will travel on to Israel, Egypt and France.
BEIJING, Sept. 18 (Xinhua) -- No newly-formed oil belt was detected in the past two days in north China's Bohai Bay from ConocoPhillips' platforms in the Penglai 19-3 oilfield, the State Oceanic Administration (SOA) said.However, new spots of visible oil spills could still be found around platform C, the SOA said in a statement on Sunday.It is estimated that about 4.51 liters of oil leaked into the sea on Saturday, a slight drop from 6.56 liters from Thursday.No oil clean-up work was done on Friday and Saturday due to the strong winds and rough conditions at sea, the statement said.ConocoPhillips China, a subsidiary of U.S. energy giant ConocoPhillips, first reported spills to authorities in June. The oil spills have polluted more than 5,500 square km of sea water in the Bohai Bay since June.The oil spills have spread to beaches in Hebei and Liaoning provinces. The spills have been blamed for losses in the provinces' tourism and aquatic farming industries.The company on Aug. 31 submitted a report to the SOA claiming that it had screened out all potential sources for oil spills and blocked all oil leaks.After days of evaluation, however, the SOA said on Sept. 2 that ConocoPhillips had failed to complete the clean-up.
CANBERRA, Sept. 1 (Xinhua) -- Bushranger Ned Kelly's headless body has finally been identified in Australia, more than 130 years after his execution in the Old Melbourne Gaol, Victoria's Attorney- General Robert Clark announced on Thursday.Clark said the bushranger's remains have been identified by doctors and scientists at the Victorian Institute of Forensic Medicine (VIFM).Kelly was an Irish Australian bushranger, considered by some merely a cold-blooded killer, while by others a folk hero and symbol of Irish Australian resistance against oppression by the British ruling class for his defiance of the colonial authorities. He was hanged for murder in 1880 at Old Melbourne Gaol. His daring and notoriety made him an iconic figure in Australian history, folklore, literature, art and film.The project involved collaboration with the ancient DNA laboratory EAAF in Argentina, which has worked with the VIFM on other forensic projects.Clark said "This is an extraordinary achievement by our forensic team here in Victoria," he told reporters in Melbourne on Thursday."To think a group of scientists could identify the body of a man who was executed more than 130 years ago, moved and buried in a haphazard fashion among 33 other prisoners, most of whom are not identified, is amazing." The investigation started when a skull believed to belong to Kelly was handed to the VIFM on Nov. 11, 2009.The skull handed in in 2009 was found not to be that of Ned Kelly, and Glenrowan historian Gary Deans said the next step is to find Kelly's skull."The Government should put a request in the public arena for the return of Ned Kelly's skull," he told ABC News."We know thanks to Jack Cranston, who held the skull around 1929, that it was sitting on a detective's desk. This was around the same time that remains were dug up in the Old Melbourne Gaol."I imagine that that detective or somebody else took it home."
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