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New results on a possible COVID-19 vaccine from Oxford University and drugmaker AstraZeneca suggest it is safe and about 70% effective.Some experts say that shows it is likely to win approval, but questions remain about how well it may help protect those over 55. That's a key concern for a vaccine that health officials hope to rely on around the world because of its low cost, availability and ease of use.Partial results from tests of the vaccine in the United Kingdom, Brazil and South Africa were published Tuesday by the medical journal Lancet.“Today, we have published the interim analysis of the Phase III trial and show that this new vaccine has a good safety record and efficacy against the coronavirus,” said Professor Andrew Pollard, Director of the Oxford Vaccine Group and Chief Investigator of the Oxford Vaccine Trial. “We are hugely grateful to our trial volunteers for working with us over the past eight months to bring us to this milestone.”Researchers claim the vaccine protected against disease in 62% of those given two full doses and in 90% of those initially given the half dose. However, independent experts have said the second group was too small — 2,741 people — to judge the possible value of that approach and more testing is needed.The interim analysis for efficacy was based on 11,636 participants accruing 131 symptomatic infections from the Phase III trials.In addition to the Oxford led program, AstraZeneca is conducting a large study in the US and globally. In total, Oxford University and AstraZeneca expect to enroll more than 60,000 participants globally.The company says it’s also making progress in manufacturing with a capacity of up to 3 billion doses of the vaccine in 2021 on a rolling basis, pending regulatory approval. The vaccine can be stored, transported and handled at normal refrigerated conditions for at least six months and administered within existing health care settings. 1940
Nebraska just became the first state to execute an inmate using a powerful opioid called fentanyl. The synthetic painkiller has helped drive the national opioid crisis.The execution is attracting big attention, because executions across the country have been delayed as drug companies file lawsuits to stop states from using their drugs in executions.However, Nebraska found a way to get around the issue—by using fentanyl in a mixture."Drug companies don't want to be associated with state executions,” explains Adam Graves, a college professor and ethics expert. “They don't want their products to be used for death."More and more states might start using fentanyl in the deadly cocktail used to put inmates to death. And that means states that have had to put executions on hold, might be able to resume.So why fentanyl? The drug is easy to get."In this particular case, you have to ask yourself by using that, are we not also opening up scars and rubbing salt in the wounds of families who have lost members to the opioid crisis?" says Graves.Fentanyl is also a major part of the opioid epidemic, and has been linked to 30,000 overdose deaths last year, according to the Centers for Disease Control and Prevention. 1226
NEW: Justice Ginsburg admitted to The John Hopkins Hospital for treatment of a possible infection, per Supreme Court. pic.twitter.com/dgDdcT55hi— Peter Alexander (@PeterAlexander) July 14, 2020 201
NEW YORK (AP) — Keith Raniere, a self-improvement guru whose organization NXIVM attracted millionaires and actresses among its adherents, was sentenced Tuesday to 120 years in prison.The 60-year-old was convicted of charges accusing him of turning some of his followers into sex slaves branded with his initials.The court proceeding in Brooklyn culminates several years of revelations about the organization, which charged people thousands of dollars for self improvement courses.Those people included Hollywood celebrities and others willing to endure humiliation and pledge obedience for Raniere’s vision of how to pursue perfection.Prosecutors said Raniere led what amounted to a criminal enterprise. Co-conspirators helped recruit and groom sexual partners for him.Raniere’s sentencing comes about a month after Clare Bronfman, a wealthy benefactor of his, was sentenced to seven years in prison in the case.The Seagram’s liquor fortune heir was taken into custody to begin her 81-month sentence immediately after her appearance in federal court in Brooklyn on Sept. 30.Bronfman admitted in a guilty plea last year that she committed credit card fraud on behalf of Raniere. 1185
NEW YORK (AP) — With NFL training camps set to start at the end of the month, the league believes it is one step closer to addressing player safety amid the coronavirus pandemic.It has come up with face shields for the players' helmets.The face shield was designed by Oakley, which already provides visors for the players. 330
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