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The US Food and Drug Administration approved two cancer treatments, Vitrakvi and Xospata, this week after expedited reviews.Vitrakvi, approved Monday, is "a treatment for adult and pediatric patients whose cancers have a specific genetic feature (biomarker)."The FDA said in a statement that it is the second approved cancer treatment that is based on a tumor biomarker instead of the place in the body where the tumor originated.Vitrakvi will be used for the treatment of solid tumors that have an NTRK (neurotrophic receptor tyrosine kinase) gene fusion that do not have a known resistance mutation, that are not metastatic or where surgical removal is likely to lead to severe morbidity, and that have no alternative treatments or have progressed after treatments.NTRK genes are rare but occur in many types of cancer, the FDA said, such as mammary analogue secretory carcinoma and infantile fibrosarcoma.Xospata tablets, approved Wednesday, are for the "treatment of adult patients who have relapsed or refractory acute myeloid leukemia (AML) with a FLT3 mutation," according to the FDA.Alongside the tablets, the agency also approved a diagnostic to detect the mutation."Approximately 25 to 30 percent of patients with AML have a mutation in the FLT3 gene. These mutations are associated with a particularly aggressive form of the disease and a higher risk of relapse," Dr. Richard Pazdur, director of the FDA's Oncology Center of Excellence, said in the statement.AML is a rapidly progressing cancer that affects the numbers of normal blood cells and calls for continuous transfusions, the FDA said.Both treatments were granted Priority Review designation.Priority Review, established in 1992, means the FDA aims to review the drug or treatment within six months, opposed to 10 months for a standard review."A Priority Review designation will direct overall attention and resources to the evaluation of applications for drugs that, if approved, would be significant improvements in the safety or effectiveness of the treatment, diagnosis, or prevention of serious conditions when compared to standard applications," the FDA says.Both treatments also received?orphan drug?designation, a status granted to drugs for rare diseases or conditions. 2261

The topics to be discussed during the first presidential debate next week include “the integrity of the election,” according to the official list released Tuesday by the nonpartisan Commission on Presidential Debates.President Donald Trump and Former Vice President Joe Biden will face-off for the first time on September 29 in Cleveland. Chris Wallace, a host on Fox News, will moderate the debate.The debate will have six, 15-minute segments. Wallace selected the topics, not necessarily to be brought up in this order:The Trump and Biden RecordsThe Supreme CourtCovid-19The EconomyRace and Violence in our CitiesThe Integrity of the ElectionThis list is subject to change before the debate if there are large news developments.The debate on September 29 will be held at Case Western Reserve University in Cleveland, Ohio. This debate was originally scheduled to take place at the University of Notre Dame, however they withdrew citing coronavirus pandemic concerns.Trump and Biden will debate two more times, on October 15 and 22. Vice President Mike Pence and Senator Kamala Harris will have their debate on October 7. 1130

The Twitter account that once belonged to former Republican presidential candidate Herman Cain tweeted Sunday evening that new CDC info indicated that COVID-19 "isn't as deadly" as once thought — despite the fact that Cain himself died of the virus just weeks ago.Cain died of COVID-19 on July 30 — four weeks after his office announced that he had been hospitalized in connection with the disease.On Aug. 11, Cain's daughter said in an update on his website that his family and campaign staff would continue to post content on the web and operate under the moniker "The Cain Gang.""He would have wanted us to do this. And that's exactly what we're going to do," Cain's daughter, Dr. Melanie Cain Gallo, wrote on HermanCain.com.In the weeks since the announcement, Cain's Twitter account has actively been sharing news links from largely conservative-leaning news outlets. On Sunday evening, the account tweeted a link to a story about a recent CDC announcement stating that COVID-19 was only listed as the sole cause of death for 6% of those killed by the virus."It looks like the virus is not as deadly as the mainstream media first made it out to be," the "Cain Gang" wrote on Twitter. 1196

The Yale University police officers who were called to investigate a napping black graduate student ultimately admonished the white student who had contacted police in the first place, a Yale vice president says.The incident, captured in two Facebook Live videos, has sparked outrage about racial profiling and policing.Kimberly Goff-Crews, Yale's vice president for Student Life, said in an email to students Wednesday night that she's been "deeply troubled" by the incident.Officers interrogated Lolade Siyonbola, a black graduate student at Yale, early Tuesday after a white student found her sleeping in a common room of their dorm and called police.Siyonbola had been working on a paper in the Hall of Graduate Studies and fell asleep. Another student came in, turned on the lights and told her, "You're not supposed to be sleeping here. I'm going to call the police."Two police officers arrived and began questioning Siyonbola in a stairwell. When she asked them about the complaint, one officer said, "She called us (and) said there's somebody who appeared they weren't ... where they were supposed to be."The officers asked for her ID, and after some delay in verifying the spelling of her name, she was cleared to go.In the aftermath, Yale officials have defended the police response to the situation."We believe the Yale police who responded followed procedures," said Yale spokeswoman Karen Peart. "It is protocol in such circumstances for the police to ask for student (or staff) identification cards. Both students had to identify themselves."CNN has reached out to the other student for comment.The delay with verifying Siyonbola's ID was because the name on her card was her preferred name, which did not exactly match her name in university records, Peart said."As we do with every incident, we will be reviewing the call and the r

The United States is demanding that all United Nations sanctions be reimposed against Iran, a move that follows America’s embarrassing defeat to extend an arms embargo against Tehran. President Donald Trump says Secretary of State Mike Pompeo will travel to New York on Thursday to notify the Security Council president that the U.S. is invoking the so-called “snapback” mechanism in the council’s resolution that endorsed the 2015 Iran nuclear deal. Other nations claim the U.S. has no standing to make the move because the Trump administration pulled the U.S. out of the Iran nuclear deal two years ago."Today, I am directing the Secretary of State Mike Pompeo to notify the UN Security Council that the United States intends to restore virtually all of the previously suspended United Nations sanctions on Iran," Trump said. 836

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