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WASHINGTON, Dec. 7 (Xinhua) -- Drugs that affect the levels of an important brain protein involved in learning and memory reverse cellular changes in the brain seen during aging, according to an animal study published Wednesday in the Journal of Neuroscience. The findings could one day aid in the development of new drugs that enhance cognitive function in older adults.Aging-related memory loss is associated with the gradual deterioration of the structure and function of synapses (the connections between brain cells) in brain regions critical to learning and memory, such as the hippocampus.Recent studies suggested that histone acetylation, a chemical process that controls whether genes are turned on, affects this process. Specifically, it affects brain cells' ability to alter the strength and structure of their connections for information storage, a process known as synaptic plasticity, which is a cellular signature of memory.In the current study, Cui-Wei Xie, of the University of California, Los Angeles, and colleagues found that compared with younger rats, hippocampi from older rats have less brain-derived neurotrophic factor (BDNF) -- a protein that promotes synaptic plasticity -- and less histone acetylation of the Bdnf gene. By treating the hippocampal tissue from older animals with a drug that increased histone acetylation, they were able to restore BDNF production and synaptic plasticity to levels found in younger animals."These findings shed light on why synapses become less efficient and more vulnerable to impairment during aging," said Xie, who led the study. "Such knowledge could help develop new drugs for cognitive aging and aging-related neurodegenerative diseases, such as Alzheimer's disease," she added.

BEIJING, Jan. 9 (Xinhua) -- China's official website for booking train tickets received a daily average of more than 1 billion hits during the first week of January, according to a railway official.Hu Yadong, vice minister of railways, said Sunday that the online ticket sales platform has provided consumers with a convenient way to buy tickets. He also addressed complaints about the fairness of the sales process."Train tickets sold online or by telephone have topped 2 million daily, meaning that around one-third of passengers don't have to wait in line at train stations for several hours to get a ticket," Hu said.However, many Chinese have expressed dissatisfaction with the website, with some people unable to get train tickets home for this year's Spring Festival holiday, a major holiday in China.Several customers posted their complaints on popular microblogging website weibo.com, stating that the booking site often failed due to "too many visits at the same time."The Spring Festival holiday is always a difficult time for China's public transportation authorities. A total of 3.16 billion passenger trips are expected during the holiday, up 9.1 percent from a year earlier, of which 235 million trips will be made via the country's railways, up 6.1 percent year-on-year, said Hu.This year's transport rush in the Spring Festival Season started on Sunday and will end on Feb. 16, according to the Ministry of Railways.

SAN FRANCISCO, Dec. 2 (Xinhua) -- About one in 10 mobile phone subscribers in the United States is now using an Apple iPhone, said a new survey released on Friday.Latest survey results from research firm comScore showed that for the three-month period ending in October, Apple remained the No. 4 handset maker in the U.S. with its share of mobile subscribers rising to 10.8 percent from 9.5 percent in the previous three months.Among the top five mobile phone brands in the U.S. market, Apple is the only one that saw its market share increase in the quarter, according to the survey.Samsung was still the top handset manufacturer with 25.5 percent of U.S. mobile subscribers, followed by LG and Motorola taking the second and third place with 20.6 percent and 13.6 percent of share respectively.Research in Motion (RIM), maker of Blackberry, ranked No. 5 with a share of 6.6 percent.Except Apple, market shares of the other four brands remained unchanged or dropped from the previous quarter.Apple's gain in the quarter might be driven by the introduction of new model iPhone 4S which went on sale on Oct. 14, and the addition of Sprint as a carrier in the U.S. market, some analysts said.The survey by comScore, which involved more than 30,000 U.S. mobile subscribers, found that 234 million Americans age 13 and older used mobile devices by the end of October.

BEIJING, Nov. 17 (Xinhua) -- Chinese State Councilor Liu Yandong on Thursday met with a U.S. artist delegation, vowing to promote bilateral cultural and art exchanges.Headed by President and Chief Executive Officer of the Asia Society Vishakha Desai, the delegation will participate in the China-U.S. Forum on the Arts and Culture from Nov. 16-19 in Beijing.Liu welcomed the U.S. artists, noting cultural and art exchanges are an important component of bilateral people-to-people exchanges.She said the founding of the forum established an institutionalized and constructive platform for deepening bilateral relations and friendship between the two peoples.Artists from the two countries should exert their influence and actively promote bilateral cultural exchanges, she said.The forum is organized by the Chinese People's Association for Friendship with Foreign Countries, the Asia Society and the Aspen Institute.An extraordinary line-up of American cultural icons will attend the event, including actress Meryl Streep, film director Joel Coen, musician Yo-Yo Ma, and best-selling author Amy Tan.