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WASHINGTON, Aug. 4 (Xinhua) -- U.S. scientists have found two gene mutations occurring in oligodendrogliomas, the second-most common form of brain cancer, according to a study to be published Friday in journal Science.For years scientists have been looking for the primary cancer genes involved in oligodendrogliomas evolvement. Scientists know the two chromosomes held the probable mutations, but the particular gene information remains unclear.Now scientists at Duke University Medical Center and Johns Hopkins University have discovered the most likely genetic mutations that researchers have been hunting for on chromosomes 1 and 19.The genes they identified, CIC or FUBP1, are tumor suppressor genes. The cancer-related pathways that involve these genes could become targets for future treatments, said Hai Yan, a Duke associate professor of pathology and co-corresponding author of the study.The researchers found CIC on chromosome 19 and FUBP1 on chromosome 1 based on an initial study of seven oligodendrogliomas. They found six mutations and two mutations, respectively, in the seven tumors. Further study of 27 more of these tumors showed that there were 12 and three mutations of CIC and FUBP1, respectively. The two genes were rarely mutated in other types of cancers, indicating that they are oligodendroglioma-specific genes.These genes were difficult to find until the technology improved, said Yan."The team used whole genome sequencing technology so that no genes would be excluded, and we found to our surprise that one gene, on chromosome 19, was mutated in six out of the seven initial tumor specimens we sequenced," Yan said. "A mutation frequency of 85 percent is very high."The finding of two additional new genes involved in oligodendrogliomas increases the chances for an effective combination drug therapy for the tumor, Yan said. He envisions a combination cocktail of drugs similar to the combination-drug treatments taken by HIV patients that would target different pathways involved in cancer, and assist both in reducing the chance of relapsing and increasing odds of success.

CANBERRA, June 6 (Xinhua) -- Australian beef is not to blame for a recent outbreak of E.coli in Japan, Meat and Livestock Australia confirmed on Monday.Twenty people have fallen ill in Japan's Toyama prefecture, with 15 of them infected with the O157 strain of E.coli after eating at a popular Korean-style barbecue restaurant chain, Gyukaka, on May 6.The operators of the restaurant chain, REINS International, said they suspected the bacterium might have been carried by beef imported from Australia.After conducting an investigation into the Japanese outbreak, regional manager for Meat and Livestock Australia, Melanie Brock, said testing shows Australian beef was not the source of the outbreak."The Toyama prefecture health authorities have confirmed following a thorough inspection that imported Australian beef was not the source of an incident of E.coli," Brock said in a statement on Monday."The authorities continue to investigate other food consumed by the affected customers."Brock said Australian beef has long been recognized by the Japanese trade and consumers for its strong safety record.Brock added that Australian beef for export to Japan is processed under the veterinary supervision of the Australian Quarantine and Inspection Service, and is recognized internationally as bearing a high hygienic standard.

WASHINGTON, Aug. 11 (Xinhua) -- The unique fossils of an adult plesiosaur and its unborn baby may provide the first evidence that these ancient animals gave live birth like mammals, according to a new study to be published Friday in the journal Science.The 78-million-year-old, 15.4-foot-long (4.7-meter-long) adult specimen is a Polycotylus latippinus, one of the giant, carnivorous, four-flippered reptiles that lived during the Mesozoic Era.Dr. Robin O'Keefe of Marshall University in West Virginia and Dr. Luis Chiappe, Dinosaur Institute director of the Natural History Museum in Los Angeles County, have determined that it is the fossil of an embryonic marine reptile contained within the fossil of its mother.The embryonic skeleton contained within shows much of the developing body, including ribs, 20 vertebrae, shoulders, hips, and paddle bones.O'Keefe and Chiappe have also determined that plesiosaurs were unique among aquatic reptiles in giving birth to a single, large offspring, and that they may have lived in social groups and engaged in parental care.Although live birth has been documented in several other groups of Mesozoic aquatic reptiles, no previous evidence of it has been found in the important order of plesiosaurs."Scientists have long known that the bodies of plesiosaurs were not well suited to climbing onto land and laying eggs in a nest," O'Keefe said."So the lack of evidence of live birth in plesiosaurs has been puzzling. This fossil documents live birth in plesiosaurs for the first time, and so finally resolves this mystery."

BEIJING, July 15 (Xinhua) -- The Chinese Academy of Agricultural Sciences (CAAS) announced Friday that a group of international scientists has finished sequencing the genetic code of the potato.The Potato Genome Sequencing Consortium (PGSC), which is led by Chinese scientists and made up of 97 researchers from 14 countries, has sequenced the complete potato genome and published a report of its findings in the latest issue of the scientific journal Nature, said the CAAS.The research took six years and revealed that the potato contains about 39,000 genes, said the CAAS.Qu Dongyu, a potato farming specialist with the Crop Science Society of China and a promoter of the PGSC, said the study helped discover genes that define the growth and insect resistance of potatoes.The sequenced genome will enable scientists to create new varieties of potato that are high in yield and quality and more resistant to insects and diseases, he said.Huang Sanwen, a researcher with the CAAS and one of the three corresponding authors of the report, said the sequencing will also allow potato breeders to accelerate the breeding process of new seeds from 10 to 12 years to about 5 years.China is the world's top potato grower, with its farmers planting potatoes on nearly 90 million mu (6 million hectares) of land each year. The average yield per mu stands at 1,000 kg, only one-third of that harvested by countries with advanced technologies, Qu said.

WASHINGTON, July 27 (Xinhua) -- Astronomers studying observations taken by NASA's Wide-field Infrared Survey Explorer (WISE) mission have discovered the first known "Trojan" asteroid orbiting the sun along with Earth, the U.S. National Aeronautics and Space Administration (NASA) announced Wednesday in a statement.Trojans are asteroids that share an orbit with a planet near stable points in front of or behind the planet. Because they constantly lead or follow in the same orbit as the planet, they never can collide with it. In our solar system, Trojans also share orbits with Neptune, Mars and Jupiter. Two of Saturn's moons share orbits with Trojans.Scientists had predicted Earth should have Trojans, but they have been difficult to find because they are relatively small and appear near the sun from Earth's point of view."These asteroids dwell mostly in the daylight, making them very hard to see," said Martin Connors of Athabasca University in Canada, lead author of a new paper on the discovery to be published Thursday in the journal Nature. "But we finally found one, because the object has an unusual orbit that takes it farther away from the sun than what is typical for Trojans. WISE was a game-changer, giving us a point of view difficult to have at Earth 's surface."The WISE telescope scanned the entire sky in infrared light from January 2010 to February 2011. Connors and his team began their search for an Earth Trojan using data from NEOWISE, an addition to the WISE mission that focused in part on near-Earth objects, or NEOs, such as asteroids and comets. NEOs are bodies that pass within 28 million miles (45 million kilometers) of Earth 's path around the sun. The NEOWISE project observed more than 155, 000 asteroids in the main belt between Mars and Jupiter, and more than 500 NEOs, discovering 132 that were previously unknown.The team's hunt resulted in two Trojan candidates. One called 2010 TK7 was confirmed as an Earth Trojan after follow-up observations with the Canada-France-Hawaii Telescope on Mauna Kea in Hawaii.The asteroid is roughly 1,000 feet (300 meters) in diameter. It has an unusual orbit that traces a complex motion near a stable point in the plane of Earth's orbit, although the asteroid also moves above and below the plane. The object is about 50 million miles (80 million kilometers) from Earth. The asteroid's orbit is well-defined and for at least the next 100 years, it will not come closer to Earth than 15 million miles (24 million kilometers).