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For the past two years, 52-year-old Kendra Jackson of Omaha, Nebraska just thought she had a bad cold."When it first started out, I just thought it was my allergies or a runny nose -- like the beginning of a fresh cold," Jackson said.The coughing, sneezing and runny nose began 2? years after Jackson was involved in a serious car accident. She remembers hitting her face against the dashboard, and she has struggled with migraine headaches ever since.In 2015, Jackson's "runny nose" began to worsen."When it didn't go away, I kept going back and forth to the doctors, and they prescribed every kind of medicine you can think of, and my nose just kept on running," she said.The doctors she saw told her that she probably had allergies. But this year, Jackson went to physicians at the University of Nebraska Medical Center and learned the real reason behind her nasal discharge: a cerebrospinal fluid (or CSF) leak caused by a small hole in her skull."She would wake up in the morning after sleeping upright in a chair, and the whole front of her shirt was wet with fluid. It was a lot of fluid," said Dr. Christie Barnes, a rhinologist at the University of Nebraska Medical Center and a lead surgeon on the case.Jackson said she was losing about half a liter of fluid per day.A physician's assistant "astutely recognized right away that this was something different than a runny nose and was consistent with a CSF leak. So we had her collect her fluids and sent it off for evaluation," Barnes said.Cerebrospinal fluid is a clear, colorless fluid that surrounds and protects the brain and spinal cord. The fluid also helps to remove waste products from the brain and distribute nutrients and other substances throughout the central nervous system, according to the Cleveland Clinic."CSF is a fluid that actually bathes the brain. Because the skull is a fixed box and the brain is a nice soft organ, it needs to be protected from moving around inside that hard box," Barnes said. "So it actually provides a cushion for the brain and the spinal cord."Cerebrospinal fluid is produced continuously in the brain and is normally absorbed into the bloodstream through protrusions in the outer membrane of the brain, called the dura mater.But in Jackson's case, a tiny hole in her cribriform plate -- a thin bone that separates her cranial and nasal cavities -- allowed the fluid to drip into her nose and mouth, resulting in her symptoms.According to Barnes, this part of the skull is "very thin, less than a potato chip. And it's one of the most common locations for this type of a CSF leak," Barnes said.Cerebrospinal fluid leaks are relatively rare, occurring in approximately five in 100,000 individuals worldwide every year. They are most commonly caused by trauma or surgery, according to the CSF Leak Association.In Jackson's case, the physicians believe that her car accident may have caused a small hole that increased in size over time."She was rear-ended and had head trauma, so it's certainly possible," Barnes said. "It may have caused a bit of a thin area there. Her symptoms actually started a little bit after (the accident), so for her, I think there's probably a combination of both the trauma and the increased pressure."Depending on the amount of fluid loss, cerebrospinal fluid leaks can be life-threatening. They also place the patient at an increased risk of infections such as meningitis, according to Barnes.In order to treat Jackson's condition, physicians at the University of Nebraska Medical Center performed a surgery that plugged the hole in her skull using tissue from her nose and abdomen, Barnes said."I used tissue from the inside of her nose to plug the leak," Barnes said. "I also borrowed some abdominal fat; it makes a great plugging agent in this location, so with just a tiny bit of fat, I was able to plug the leak."Almost a month after the surgery, Jackson is back home and reports that the mysterious drip has disappeared."I don't have the nasal drip anymore, but I still have the headaches," she said. "I actually feel pretty good, and I'm able to get a little bit of sleep."Though her condition is rare, Jackson wants people to know that cerebrospinal fluid leaks can occur, particularly after head trauma: "For people who hear my story, if they're tasting a very salty taste and something's draining in the back of your throat, it's probably something other than allergies. So get to the doctor." 4474

Former FBI Director James Comey sat down with Stephen Colbert on Tuesday for a wide-ranging interview that touched on President Donald Trump, the Russia investigation and...red wine."When you were fired, you say in the book that when it was over, you flew back on a plane to the east coast drinking Pinot Noir in a paper cup," Colbert said during a Tuesday afternoon taping of CBS' "The Late Show."He then pulled out the bottle of wine and two paper cups and made a toast with Comey."To the truth," he said.CNN was granted exclusive access to the taping of the interview, which is set to air in late night on Tuesday. "The Late Show" is Comey's latest stop in his book tour for "A Higher Loyalty," a new memoir that offers insight into his termination as FBI director by President Trump. The book, which officially went on sale Tuesday, is shaping up to be one of the biggest best-sellers of the year. Comey's publisher printed 850,000 copies to meet the expected demand from buyers."Of all the people to be fired by Donald Trump, my guest tonight is definitely one of them," Colbert said when he introduced Comey, who walked out on the CBS stage to a standing ovation.The two talked for more than 30 minutes with Colbert kicking off the conversation by asking Comey for his loyalty and if he has insight into the Russia investigation that isn't public yet."Yes," Comey replied."Can you tell me?" Colbert asked."Uh, no," Comey answered."Okay, drink some more wine," Colbert said.The conversation moved quickly and culminated in a lightning round of questions."What happens if [Special Counsel Robert] Mueller gets fired," Colbert asked. "Does the investigation go on?""I think most likely it goes on. I think you would need to fire everyone in the Justice Department and the FBI to stop that investigation," Comey replied. "I think it would be very hard to shut that down by firing [Mueller].""Well, it's hard to fire the FBI director, too," Colbert said."The Late Show" had some fun hyping the interview by tweeting out a mock promo earlier this week that parodied ABC News' ads for its exclusive sit-down.Colbert's promo used footage from Sunday's ABC interview and put Colbert in the seat of anchor George Stephanopoulos. It billed "The Late Show" conversation as Comey's "first interview since that other interview" and had Colbert "ask" Comey questions like "You have to choose one superpower. Is it invisibility or flight?" and "Are you a cop?"Comey will continue with his book tour on "The View" on Wednesday, "The Lead with Jake Tapper" on CNN and MSNBC's "The Rachel Maddow Show" on Thursday and he will participate in a CNN town hall on Friday.Colbert's relentless mockery of the Trump administration has helped him top his rivals in TV ratings by a sizable margin. Ratings reports on Monday showed that Colbert averaged 4 million viewers in the first quarter of 2018, which amounts to a 20% spike compared to 2017 and a staggering 1.2 million more viewers than rival Jimmy Fallon.With numbers like that, it's not likely that Colbert is going anywhere. An audience member on Tuesday asked him ahead of the taping if he could have any job in the Trump White House, which one would he want."I don't think I'd be a good president, but I'd be a better president," Colbert said. "Just nothing in HR." 3353

FILE - In this Monday, Oct. 22, 2018 file photo shows the Plumpjack Wine & Spirits store, in San Francisco, part of the Plumpjack Group collection of wineries, bars, restaurants, hotels and liquors stores. ncoming California governor Gavin Newsom says he'll give up control of his wine and hospitality business to avoid conflicts of interest. Spokesman Nathan Click says Newsom is transferring the title and control of his PlumpJack Group to a blind trust. PlumpJack Group includes four hotels; four Napa Valley wineries; several bars and restaurants; two wine and liquor stores in San Francisco; and an online liquor store. Newsom also plans to publicly release his tax returns every year he's governor. (AP Photo/Eric Risberg, File) 746

Fired FBI Director James Comey said in an interview that aired Tuesday morning that the FBI's credibility is worse now than it was a few years ago but would be even worse had it not been for his actions leading the bureau."It's worse. But again, people can disagree about this. And people I respect will. But my judgment is it would be worse today had we not picked the least bad alternative," Comey said, speaking with NPR's "Morning Edition." "I think the decisions that we had to make and lots of other follow-ons, sure, the Department of Justice's and the FBI's reputation has been hurt," he continued. 614

Forget about drones and armies of people driving Amazon trucks. One big Wall Street firm thinks Amazon's plan to build up its air freight delivery service may be what really winds up hurting UPS and FedEx.Morgan Stanley analyst Ravi Shanker said in a report Tuesday that both delivery giants could lose 10% of their revenue to Amazon Air by 2025. Shanker cut his price targets on UPS (UPS) and FedEx (FDX) and both stocks plunged more than 6% as a result.It was a particularly gruesome day for transportation stocks due to worries about the broader economy and confusion about the status of US-China trade talks.The Dow Jones Transportation Average, which includes FedEx and UPS as well as leading airlines, truckers and railroads, fell 4.4% -- its worst drop since June 2016.But Shanker paints a picture that should be extremely worrisome to UPS and FedEx.He notes that Amazon (AMZN), which currently is leasing 40 cargo jets, could eventually have 100 planes running and estimates that the planned Amazon Air routes could overlap with more than two-thirds of the volume flown by UPS and FedEx.That's bad news for both companies since Shanker said that UPS and FedEx each generate nearly 20% of their overall revenue from US air deliveries.Amazon has made big investments to bulk up Amazon Air. In the past few years, it has bought stakes in two freight delivery airlines -- Air Transport Services Group (ATSG) and Atlas Air Worldwide Holdings (AAWW).It also announced plans to invest .5 billion in order to build an Amazon Air hub on more than 900 acres of land that it is leasing near the Cincinnati/Northern Kentucky International Airport. Amazon bought an additional 210 acres earlier this year.There's a simple reason why Amazon will want to handle more of its own air deliveries. According to Shanker, Amazon could save between billion and billion next year. That works out to about 3% to 6% of its global shipping costs.But on a day when the broader market was tanking, investors didn't seem too enthusiastic about Shanker's thoughts on Amazon either. Shares of Amazon fell nearly 6%. 2113